JP2012508769A - オルガノゲル組成物及び製造方法 - Google Patents
オルガノゲル組成物及び製造方法 Download PDFInfo
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- JP2012508769A JP2012508769A JP2011536521A JP2011536521A JP2012508769A JP 2012508769 A JP2012508769 A JP 2012508769A JP 2011536521 A JP2011536521 A JP 2011536521A JP 2011536521 A JP2011536521 A JP 2011536521A JP 2012508769 A JP2012508769 A JP 2012508769A
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- Prior art keywords
- thermoreversible
- lecithin
- organogel
- structured
- phospholipid organogel
- Prior art date
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Abstract
【選択図】なし
Description
に変換されている。逆格子空間のプロットである1/dh、k、l 対6つのすべての回折ピークの(h2+k2+l2)1/2の値は、R=0.9984の直線性を示している。インデックススペースは、格子定数104Åを有する立方体対称の空間群Fm3mに変換できる。この値は、R.Efat、A、Aserin、E.Kesselman、D.Danino、E.Wachtel、及びN.Garti著、コロイド及び表面 A:物理化学と工学的側面 299(2007)、133−145頁で測定されたモノオレイン−水−エタノールの立方体共連続相から導き出されたものに類似していた。
に変換されている。0.692、0.7783、1.1288、1.318、1.3763、1.7759、1.9531、及び2.0606nmにおける8つの大きなピークをもって示している。逆格子空間のプロットである1/dh、k、l 対6つのすべての回折ピークの(h2+k2+l2)1/2の値は、R=0.9999の直線性を示している。インデックススペースは、格子定数157Åを有する立方対称の空間群Fm3mと変換できる。この値は、130Å格子定数を有する立方体共連続相の存在のためのGMO−水−混合物から導き出されたものに類似していた。これは、R.Efat、A、Aserin、E.Kesselman、D.Danino、E.Wachtel、及びN.Garti著、コロイド及び表面A:物理化学と工学的側面299(2007)、133−145頁で述べられているように、添加されたグリセロールと立方液晶に組み込まれたビタミンEアセテートのより大きい分子の影響といえる。
Claims (20)
- 熱可逆的で構造化されたリン脂質オルガノゲル組成物であって、
リン脂質組成物と;
有機溶媒と;
水溶性ポリマーと;及び
極性溶媒と;
を具えることを特徴とする熱可逆的構造化されたリン脂質オルガノゲル組成物。 - 前記水溶性ポリマーが、バイオベースであることを特徴とする請求項1に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記有機溶媒が、ミリスチン酸イソプロピル、ラウリン酸エチル、ミリスチン酸エチル、パルミチン酸イソプロピル、シクロペンタン、シクロオクタン、トランス−デカリン、トランス−ピナン、n−ペンタン、n−ヘキサン、n−ヘキサデカン、トリプロピルアミン、1,7−オクタジエン、ラウリン酸ブチル、シクロドデカン、ジブチルエーテル、イソオクタン、n−オクタン、トリブチルアミン、トリイソブチルアミン、鉱油、トリグリセリド及び/又はジグリセリド油などの植物油、ポリオールエステル、モノグリセリド、ジグリセリド、脂肪酸エステル、及びそれらの組み合わせから成る群から選択されることを特徴とする請求項1又は2に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記極性溶媒が、水、グリセロール、エチレングリコロール、プロピレングリコロール、ホルムアミド、イソソルビド、イソソルビド誘導体、ソルビトール、エリスリトール、その他の多価アルコール、及びそれらの組み合わせから成る群から選択されることを特徴とする請求項1乃至3のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記熱可逆的で構造化されたリン脂質オルガノゲル組成物を30−40℃の温度に加熱すると、前記熱可逆的で構造化されたリン脂質オルガノゲル組成物が融解し、前記熱可逆的で構造化されたリン脂質オルガノゲル組成物を30℃より低い温度に冷却すると、前記熱可逆で構造化されたリン脂質オルガノゲル組成物がゲルの形状を再形成することを特徴とする請求項1乃至4のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 更に、緑茶エキス、香料、アスコリビン酸、ソルビン酸カリウム、クエン酸、天然極性酸化防止剤、トコフェノール、ステロール、植物スレロール、ノコギリヤシ、カフェイン、海藻エキス、グレープシードエキス、ローズマリーエキス、アーモンドオイル、ラベンダーオイル、ペパーミントオイル、ブロメライン、カプサイシン、塩化ベンザルコニウム、トリクロサン、パラクロメタキシレノール(PCMX)、ヒアルロン酸、乳化剤、又はこれらの組み合わせから成る群から選択される化合物を具えることを特徴とする請求項1乃至5のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 更に、麻酔薬、非ステロイド性高炎症薬、筋弛緩剤、ステロイド、ホルモン、鎮痛剤、制吐剤、心・血管作動薬、抗甲状腺薬、高分子、神経障害薬、殺菌剤、消毒剤、又はこれらの組み合わせから成る群から選択される化合物を具えることを特徴とする請求項1乃至6のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記熱可逆的で構造化されたリン脂質オルガノゲル組成物が、ASTMラジオアイソトープ標準方法D6866により決定されるバイオベースであることを特徴とする請求項1乃至7のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記リン脂質組成物が、90%より低いリン脂質、30%より低いホスファチジルコリン、又は10−95%のホスファチジルコリンを具えることを特徴とする請求項1乃至8のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記水溶性ポリマーが、キサンタンガム、ジェランガム、セルロース、及び変性セルロース産物、デンプン、キチン、カラギーナン、アラビアゴム、アルギン酸、アカシアゴム、グアーゴム、寒天、ゼラチン、ローカストビーンガム、イヌリン、マルトデキストリン、ペクチン、ベータグルカン、及びそれらの組み合わせから成る群から選択されることを特徴とする請求項1乃至9のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 前記水溶性ポリマーが、脱油レシチンと混合されることを特徴とする請求項1乃至10のいずれか1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物。
- 請求項1乃至11のいずれかに1項に記載の熱可逆的で構造化されたリン脂質オルガノゲル組成物の、食品、化粧品、パーソナルケア製品、又は工業製品における使用。
- 製品を生産する工程において、当該工程が、
有機溶媒とリン脂質を混合して、有機相を生成するステップと;
水溶性ポリマーを極性溶媒に分散し、極性相を生成するステップと;及び
前記有機相と前記極性相を混合するステップと;
を具えることを特徴とする工程。 - 更に、緑茶エキス、香料、アスコリビン酸、ソルビン酸カリウム、クエン酸、天然極性酸化防止剤、トコフェノール、ステロール、植物ステロール、ノコギリヤシ、カフェイン、海藻エキス、グレープシードエキス、ローズマリーエキス、アーモンドオイル、ラベンダーオイル、ペパーミントオイル、ブロメライン、カプサイシン、塩化ベンザルコニウム、トリクロサン、パラクロメタキシレノール(PCMX)、ヒアルロン酸、乳化剤、極性ゲスト分子、非極性ゲスト分子、両親媒性ゲスト分子、酵素、及びこれらの組み合わせから成る群から選択される化合物を前記有機相、前記極性相、又はこれらの組み合わせに添加するステップ、を更に具えることを特徴とする請求項13に記載の工程。
- 前記有機溶媒と前記リン脂質組成物が、連続的に撹拌されて混合されることを特徴とする請求項13又は14に記載の工程。
- 前記水溶性ポリマーが、連続的に撹拌されて前記極性溶媒に分散されることを特徴とする請求項13乃至15のいずれか1項に記載の工程。
- 前記工程が、大気温度と低剪断で行なわれることを特徴とする請求項13乃至16のいずれか1項に記載の工程。
- 熱可逆的で構造化されたリン脂質オルガノゲルの装填方法において、前記方法が: 前記熱可逆的で構造化されたリン脂質オルガノゲルを融解させるステップと;
化合物と前記熱可逆的で構造化されたリン脂質オルガノゲルを混合するステップと;及び
前記化合物を含有する熱可逆的で構造化されたリン脂質オルガノゲルをゲルを融点より低い温度に冷却して、前記熱可逆的で構造化されたリン脂質オルガノゲルがゲル形状を再形成するステップと;
を具えることを特徴とする熱可逆的で構造化されたリン脂質オルガノゲルの装填方法。 - 前記化合物が、疎水性化合物、親水性化合物、両親媒性化合物、及びそれらの組み合わせから成る群から選択されることを特徴とする請求項18に記載の熱可逆的で構造化されたリン脂質オルガノゲルの装填方法。
- 前記熱可逆的で構造化されたリン脂質オルガノゲルを食品、化粧品、パーソナルケア製品、又は工業製品に組み込むステップとを更に具えることを特徴とする請求項18又は19に記載の熱可逆的で構造化されたリン脂質オルガノゲルの装填方法。
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AU2009313928A1 (en) | 2010-05-20 |
IL212839A (en) | 2016-09-29 |
CN102264352A (zh) | 2011-11-30 |
JP6073552B2 (ja) | 2017-02-01 |
KR101685218B1 (ko) | 2016-12-09 |
EP2711001A3 (en) | 2014-07-02 |
BRPI0915271A2 (pt) | 2016-06-14 |
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