KR900700079A - 누출방지 리포좀 제제 - Google Patents

누출방지 리포좀 제제

Info

Publication number
KR900700079A
KR900700079A KR1019890701687A KR890701687A KR900700079A KR 900700079 A KR900700079 A KR 900700079A KR 1019890701687 A KR1019890701687 A KR 1019890701687A KR 890701687 A KR890701687 A KR 890701687A KR 900700079 A KR900700079 A KR 900700079A
Authority
KR
South Korea
Prior art keywords
liposome
water
leak
liposome formulation
liposome preparation
Prior art date
Application number
KR1019890701687A
Other languages
English (en)
Inventor
기요다다 야스이
도시로오 히가시
유우 이마사또
Original Assignee
후지하라 도미오
다이닛뽕 세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1988/000022 external-priority patent/WO1988004974A1/ja
Application filed by 후지하라 도미오, 다이닛뽕 세이야꾸 가부시끼가이샤 filed Critical 후지하라 도미오
Publication of KR900700079A publication Critical patent/KR900700079A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

내용 없음

Description

누출방지 리포좀 제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 동결 용해후의 사람 TNF 포함율에 대한, 외수상에 가한 트레할로오스 농도의 영향을 표시하고 있으며, 제2도는 외수상에 가한 젤라틴 농도의 영향을 표시하고 있다. 도면에서 ●는 본 발명의 리포좀제제를 ○는 대조 리포좀 제제를 나타낸다.

Claims (4)

  1. 리포좀의 내수상에 젤라틴, 알부민 혹은 폴리에틸렌글리콜을 함유함을 특징으로 하는 수용성 고분자 물질을 유효성분으로 하는 동결 또는 동결 건조 리포좀 제제.
  2. 제1항에 있어서, 외수상에 당 또는 아미노산을 함유하는 동결 리포좀 제제.
  3. 제1항에 있어서, 수용성 고분자 물질이 단백질인 리포좀 제제.
  4. 제1항에 있어서, 단백질이 사람 암 괴사인자 또는 인터류킨 1인 리포좀 제제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890701687A 1988-01-12 1989-01-11 누출방지 리포좀 제제 KR900700079A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/JP1988/000022 WO1988004974A1 (en) 1987-01-12 1988-01-12 Method and apparatus for processing circumference of spectacle lens
JP5361/88 1988-01-13
JP536188 1988-01-13

Publications (1)

Publication Number Publication Date
KR900700079A true KR900700079A (ko) 1990-08-11

Family

ID=11609035

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890701687A KR900700079A (ko) 1988-01-12 1989-01-11 누출방지 리포좀 제제

Country Status (3)

Country Link
EP (1) EP0395765A4 (ko)
KR (1) KR900700079A (ko)
WO (1) WO1989006532A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4740375A (en) * 1985-02-25 1988-04-26 Technology Unlimited, Inc. Gelcores
AU612285B2 (en) * 1988-10-05 1991-07-04 Vestar, Inc. Method of making liposomes with improved stability during drying
US6805879B2 (en) * 2000-06-23 2004-10-19 Biopharm Solutions Inc. Stable polymer aqueous/aqueous emulsion system and uses thereof
TWI388344B (zh) * 2005-08-23 2013-03-11 Celsion Corp 儲存奈米微粒調合物之方法
US8962015B2 (en) * 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
WO2009062299A1 (en) * 2007-11-15 2009-05-22 Lipodur Pharmaceutical Inc. Gel-stabilized liposome compositions, methods for their preparation and uses thereof
WO2010057007A1 (en) * 2008-11-14 2010-05-20 Archer Daniels Midland Company Organogel compositions and processes for producing
CA2800315A1 (en) * 2010-05-14 2011-11-17 Archer Daniels Midland Company Food compositions comprising organogels
KR20150047336A (ko) 2013-10-24 2015-05-04 삼성전자주식회사 나노입자, 이를 제조하는 방법, 및 이의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS574913A (en) * 1980-06-11 1982-01-11 Green Cross Corp:The Urokinase preparation for oral administration
JPS58174330A (ja) * 1982-04-07 1983-10-13 Asahi Chem Ind Co Ltd ガン壊死因子の安定化法
EP0172007B1 (en) * 1984-08-10 1991-05-22 Syntex (U.S.A.) Inc. Stable liposomes with aqueous-soluble medicaments and methods for their preparation
DE3621828A1 (de) * 1986-06-28 1988-01-14 Biotest Pharma Gmbh Stabilisierung eines fuer therapeutische zwecke, insbesondere beim menschen, bestimmten interleukin-2-praeparates sowie dieses praeparat enthaltende stabilisierte waessrige loesung oder feststoff
JP2501336B2 (ja) * 1987-07-02 1996-05-29 第一製薬株式会社 安定なリポソ−ム製剤
JPS6447443A (en) * 1987-08-13 1989-02-21 Nippon Shoe Liposome

Also Published As

Publication number Publication date
WO1989006532A1 (en) 1989-07-27
EP0395765A1 (en) 1990-11-07
EP0395765A4 (en) 1991-09-25

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Legal Events

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