JP2012507293A5 - - Google Patents
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- Publication number
- JP2012507293A5 JP2012507293A5 JP2011534663A JP2011534663A JP2012507293A5 JP 2012507293 A5 JP2012507293 A5 JP 2012507293A5 JP 2011534663 A JP2011534663 A JP 2011534663A JP 2011534663 A JP2011534663 A JP 2011534663A JP 2012507293 A5 JP2012507293 A5 JP 2012507293A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- hpv
- sequence
- gene
- polymerase chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000701806 Human papillomavirus Species 0.000 claims description 48
- 238000000034 method Methods 0.000 claims description 46
- 238000003752 polymerase chain reaction Methods 0.000 claims description 28
- 101150029662 E1 gene Proteins 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 22
- 239000000523 sample Substances 0.000 claims description 15
- 108020004707 nucleic acids Proteins 0.000 claims description 14
- 150000007523 nucleic acids Chemical class 0.000 claims description 14
- 102000039446 nucleic acids Human genes 0.000 claims description 14
- 210000002700 urine Anatomy 0.000 claims description 14
- 230000000295 complement effect Effects 0.000 claims description 12
- 239000003550 marker Substances 0.000 claims description 9
- 238000001514 detection method Methods 0.000 claims description 7
- 230000002068 genetic effect Effects 0.000 claims description 7
- 239000002773 nucleotide Substances 0.000 claims description 7
- 125000003729 nucleotide group Chemical group 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 6
- 230000002441 reversible effect Effects 0.000 claims description 6
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims description 4
- 238000009396 hybridization Methods 0.000 claims description 4
- 238000007894 restriction fragment length polymorphism technique Methods 0.000 claims description 4
- XMIIGOLPHOKFCH-UHFFFAOYSA-N 3-phenylpropionic acid Chemical compound OC(=O)CCC1=CC=CC=C1 XMIIGOLPHOKFCH-UHFFFAOYSA-N 0.000 claims description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- BACYUWVYYTXETD-UHFFFAOYSA-N N-Lauroylsarcosine Chemical compound CCCCCCCCCCCC(=O)N(C)CC(O)=O BACYUWVYYTXETD-UHFFFAOYSA-N 0.000 claims description 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 claims description 2
- 101710163270 Nuclease Proteins 0.000 claims description 2
- 108091034117 Oligonucleotide Proteins 0.000 claims description 2
- 208000009608 Papillomavirus Infections Diseases 0.000 claims description 2
- 239000003463 adsorbent Substances 0.000 claims description 2
- 230000015556 catabolic process Effects 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims description 2
- 239000000356 contaminant Substances 0.000 claims description 2
- 125000004122 cyclic group Chemical group 0.000 claims description 2
- 230000003247 decreasing effect Effects 0.000 claims description 2
- 238000006731 degradation reaction Methods 0.000 claims description 2
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 claims description 2
- MOTZDAYCYVMXPC-UHFFFAOYSA-N dodecyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOS(O)(=O)=O MOTZDAYCYVMXPC-UHFFFAOYSA-N 0.000 claims description 2
- 229940043264 dodecyl sulfate Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- YQOKLYTXVFAUCW-UHFFFAOYSA-N guanidine;isothiocyanic acid Chemical compound N=C=S.NC(N)=N YQOKLYTXVFAUCW-UHFFFAOYSA-N 0.000 claims description 2
- 230000002779 inactivation Effects 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 238000002955 isolation Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 238000003753 real-time PCR Methods 0.000 claims description 2
- 230000002829 reductive effect Effects 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 108700004121 sarkosyl Proteins 0.000 claims description 2
- 238000004062 sedimentation Methods 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 238000003556 assay Methods 0.000 description 3
- 238000001712 DNA sequencing Methods 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000010369 molecular cloning Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19785008P | 2008-10-31 | 2008-10-31 | |
| US61/197,850 | 2008-10-31 | ||
| PCT/US2009/062114 WO2010051261A2 (en) | 2008-10-31 | 2009-10-26 | A genetic marker for detection of human papillomavirus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015013489A Division JP6092906B2 (ja) | 2008-10-31 | 2015-01-27 | ヒトパピローマウイルスを検出するための遺伝子マーカー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012507293A JP2012507293A (ja) | 2012-03-29 |
| JP2012507293A5 true JP2012507293A5 (enExample) | 2012-12-13 |
Family
ID=42045205
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011534663A Pending JP2012507293A (ja) | 2008-10-31 | 2009-10-26 | ヒトパピローマウイルスを検出するための遺伝子マーカー |
| JP2015013489A Expired - Fee Related JP6092906B2 (ja) | 2008-10-31 | 2015-01-27 | ヒトパピローマウイルスを検出するための遺伝子マーカー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015013489A Expired - Fee Related JP6092906B2 (ja) | 2008-10-31 | 2015-01-27 | ヒトパピローマウイルスを検出するための遺伝子マーカー |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8642261B2 (enExample) |
| EP (1) | EP2358915B1 (enExample) |
| JP (2) | JP2012507293A (enExample) |
| CN (2) | CN102333892B (enExample) |
| AU (1) | AU2009308943A1 (enExample) |
| CA (1) | CA2741762C (enExample) |
| ES (1) | ES2588251T3 (enExample) |
| HK (1) | HK1221749A1 (enExample) |
| WO (1) | WO2010051261A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013144344A2 (en) | 2012-03-30 | 2013-10-03 | Istituto Europeo Di Oncologia S.R.L. | Biomarkers for hpv infections, related diagnostic methods and kits |
| US20150376725A1 (en) * | 2013-09-04 | 2015-12-31 | Trovagene, Inc. | HPV Detection in Urine |
| TWI727156B (zh) | 2014-07-18 | 2021-05-11 | 香港中文大學 | Ｄｎａ混合物中之組織甲基化模式分析 |
| WO2017019751A1 (en) | 2015-07-27 | 2017-02-02 | The Johns Hopkins University | Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: pcr and sequencing based process methods |
| JP2020503003A (ja) | 2016-11-30 | 2020-01-30 | ザ チャイニーズ ユニバーシティ オブ ホンコン | 尿および他のサンプルにおける無細胞ｄｎａの分析 |
| WO2019013613A2 (es) | 2017-07-09 | 2019-01-17 | Hakken Enterprise Sa De Cv | Métodos y kits para determinar el riesgo de cáncer |
| TWI766225B (zh) * | 2019-01-03 | 2022-06-01 | 中國大陸商杭州諾輝健康科技有限公司 | 用於尿液樣本儲存及ｄｎａ提取之組合物及方法 |
| KR102286565B1 (ko) * | 2020-01-13 | 2021-08-05 | 대한민국 | 소변에서 결핵균 trDNA 추출용 올리고머 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2629458B2 (fr) * | 1987-07-31 | 1991-08-09 | Ire Celltarg Sa | Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain |
| US5447839A (en) * | 1988-09-09 | 1995-09-05 | Hoffmann-La Roche Inc. | Detection of human papillomavirus by the polymerase chain reaction |
| AUPN443995A0 (en) * | 1995-07-27 | 1995-08-17 | Csl Limited | Papillomavirus polyprotein |
| US20020119478A1 (en) * | 1997-05-30 | 2002-08-29 | Diagen Corporation | Methods for detection of nucleic acid sequences in urine |
| WO2006066353A1 (en) * | 2004-12-23 | 2006-06-29 | Human Genetic Signatures Pty Ltd | Detection of human papilloma virus |
| WO2007057669A2 (en) * | 2005-11-15 | 2007-05-24 | Genoid Kft. | Method of detecting pathogens |
| CN1814796A (zh) * | 2005-12-02 | 2006-08-09 | 浙江大学 | 一种用于26种人乳头瘤病毒的检测与分型的方法 |
| DE102006041970A1 (de) * | 2006-08-28 | 2008-03-06 | Genome Identification Diagnostics Gmbh | Verfahren und Mittel zum Nachweis von humanen Papillomaviren |
| EP2184368A1 (en) * | 2008-11-07 | 2010-05-12 | DKFZ Deutsches Krebsforschungszentrum | Diagnostic transcript and splice patterns of HPV16 in different cervical lesions |
-
2009
- 2009-10-26 CA CA2741762A patent/CA2741762C/en not_active Expired - Fee Related
- 2009-10-26 CN CN200980153183.8A patent/CN102333892B/zh not_active Expired - Fee Related
- 2009-10-26 JP JP2011534663A patent/JP2012507293A/ja active Pending
- 2009-10-26 WO PCT/US2009/062114 patent/WO2010051261A2/en not_active Ceased
- 2009-10-26 AU AU2009308943A patent/AU2009308943A1/en not_active Abandoned
- 2009-10-26 EP EP09797216.0A patent/EP2358915B1/en not_active Not-in-force
- 2009-10-26 CN CN201510671553.4A patent/CN105385784A/zh active Pending
- 2009-10-26 ES ES09797216.0T patent/ES2588251T3/es active Active
- 2009-10-26 US US13/126,081 patent/US8642261B2/en not_active Expired - Fee Related
-
2014
- 2014-02-04 US US14/172,793 patent/US9453265B2/en not_active Expired - Fee Related
-
2015
- 2015-01-27 JP JP2015013489A patent/JP6092906B2/ja not_active Expired - Fee Related
-
2016
- 2016-07-25 US US15/218,177 patent/US20170016078A1/en not_active Abandoned
- 2016-08-19 HK HK16109959.2A patent/HK1221749A1/zh unknown
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