JP2012506695A5 - - Google Patents
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- Publication number
- JP2012506695A5 JP2012506695A5 JP2011523864A JP2011523864A JP2012506695A5 JP 2012506695 A5 JP2012506695 A5 JP 2012506695A5 JP 2011523864 A JP2011523864 A JP 2011523864A JP 2011523864 A JP2011523864 A JP 2011523864A JP 2012506695 A5 JP2012506695 A5 JP 2012506695A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- heavy chain
- chain variable
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9047208P | 2008-08-20 | 2008-08-20 | |
| US61/090,472 | 2008-08-20 | ||
| US9723208P | 2008-09-16 | 2008-09-16 | |
| US61/097,232 | 2008-09-16 | ||
| PCT/US2009/053425 WO2010021874A2 (en) | 2008-08-20 | 2009-08-11 | Engineered anti-il-13 antibodies, compositions, methods and uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012182330A Division JP2013005805A (ja) | 2008-08-20 | 2012-08-21 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012506695A JP2012506695A (ja) | 2012-03-22 |
| JP2012506695A5 true JP2012506695A5 (enExample) | 2012-09-27 |
Family
ID=41707613
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523864A Pending JP2012506695A (ja) | 2008-08-20 | 2009-08-11 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
| JP2012182330A Pending JP2013005805A (ja) | 2008-08-20 | 2012-08-21 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012182330A Pending JP2013005805A (ja) | 2008-08-20 | 2012-08-21 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8399630B2 (enExample) |
| EP (1) | EP2328615A2 (enExample) |
| JP (2) | JP2012506695A (enExample) |
| KR (1) | KR20110043786A (enExample) |
| CN (1) | CN102264391A (enExample) |
| AR (1) | AR073088A1 (enExample) |
| AU (1) | AU2009283008A1 (enExample) |
| BR (1) | BRPI0917370A2 (enExample) |
| CA (1) | CA2734645A1 (enExample) |
| CO (1) | CO6341573A2 (enExample) |
| CR (1) | CR20110152A (enExample) |
| EA (1) | EA201170357A1 (enExample) |
| EC (1) | ECSP11010840A (enExample) |
| IL (1) | IL211087A0 (enExample) |
| MX (1) | MX2011001909A (enExample) |
| NI (1) | NI201100040A (enExample) |
| NZ (1) | NZ591098A (enExample) |
| UY (1) | UY32060A (enExample) |
| WO (1) | WO2010021874A2 (enExample) |
| ZA (1) | ZA201102081B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7306925B2 (en) | 2001-11-09 | 2007-12-11 | Vanderbilt University | Phage antibodies to radiation-inducible neoantigens |
| US7906102B2 (en) | 2001-10-03 | 2011-03-15 | Vanderbilt University | Ligands to radiation-induced molecules |
| AU2009283008A1 (en) * | 2008-08-20 | 2010-02-25 | Centocor Ortho Biotech Inc. | Engineered anti-IL-13 antibodies, compositions, methods and uses |
| GB0904214D0 (en) | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| US8580714B2 (en) * | 2009-10-14 | 2013-11-12 | Janssen Biotech, Inc. | Methods of affinity maturing antibodies |
| JOP20210044A1 (ar) * | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| WO2013019730A1 (en) * | 2011-07-29 | 2013-02-07 | The Washington University | Antibodies to tip-1 and grp78 |
| US9758591B2 (en) | 2012-08-24 | 2017-09-12 | The Regents Of The University Of California | Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis |
| AU2014249243C1 (en) * | 2013-03-13 | 2019-08-08 | Imaginab, Inc. | Antigen binding constructs to CD8 |
| WO2016014939A1 (en) | 2014-07-24 | 2016-01-28 | Washington University | Compositions targeting radiation-induced molecules and methods of use thereof |
| WO2017027325A1 (en) | 2015-08-07 | 2017-02-16 | Imaginab, Inc. | Antigen binding constructs to target molecules |
| EA037960B1 (ru) | 2016-04-27 | 2021-06-15 | Эббви Инк. | Способ лечения эозинофильного эзофагита с применением антитела против il-13 |
| MX2018016330A (es) | 2016-06-27 | 2020-02-17 | Univ California | Combinaciones para tratamiento del cáncer. |
| EP3484923A1 (en) | 2016-07-15 | 2019-05-22 | Takeda Pharmaceutical Company Limited | Methods and materials for assessing response to plasmablast- and plasma cell-depleting therapies |
| CA3046489A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
| WO2018148595A1 (en) | 2017-02-10 | 2018-08-16 | Washington University | Antibodies to tip1 and methods of use thereof |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| CN112739715A (zh) | 2018-01-12 | 2021-04-30 | 武田药品工业株式会社 | 抗cd38抗体的皮下给药 |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| WO2021119482A1 (en) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| GB201919062D0 (en) * | 2019-12-20 | 2020-02-05 | Ucb Biopharma Sprl | Antibody |
| CA3172201A1 (en) * | 2020-03-18 | 2021-09-23 | Arthur Tinkelenberg | Anti-ceramide antibodies |
| WO2025049345A1 (en) | 2023-08-25 | 2025-03-06 | Proteologix Us Inc. | Anti-il-13 multispecific antibody constructs and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217099B (hu) | 1991-03-29 | 1999-11-29 | Elf Sanofi Sa. | Eljárás citokin típusú aktivitással rendelkező fehérje, azt kódoló rekombináns DNS-szekvencia és a megfelelő transzformált sejtek és mikroorganizmusok előállítására |
| US5596072A (en) * | 1992-08-21 | 1997-01-21 | Schering Corporation | Method of refolding human IL-13 |
| US5710023A (en) | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| US7078494B1 (en) | 1996-03-01 | 2006-07-18 | Genetics Institute, Llc | Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding |
| US6664227B1 (en) | 1996-03-01 | 2003-12-16 | Genetics Institute, Llc | Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains |
| GB9625899D0 (en) | 1996-12-13 | 1997-01-29 | Glaxo Group Ltd | Substances and their uses |
| US6743604B1 (en) | 1996-12-13 | 2004-06-01 | Smithkline Beecham Corporation | Substances and their uses |
| US7553487B2 (en) | 1998-12-14 | 2009-06-30 | Genetics Institute, Llc | Method and compositions for treating asthma |
| US6472147B1 (en) | 1999-05-25 | 2002-10-29 | The Scripps Research Institute | Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries |
| WO2001023410A2 (en) | 1999-09-28 | 2001-04-05 | Genaissance Pharmaceuticals, Inc. | Drug target isogenes: polymorphisms in the interleukin 13 gene |
| US20030103978A1 (en) | 2000-02-23 | 2003-06-05 | Amgen Inc. | Selective binding agents of osteoprotegerin binding protein |
| CA2450147A1 (en) | 2001-06-07 | 2002-12-19 | Wyeth | Solution structure of il-13 and uses thereof |
| IL166244A0 (en) | 2001-07-12 | 2006-01-15 | Jefferson Foote | Super humanized antibodies |
| EP1578912A4 (en) * | 2001-10-26 | 2007-12-26 | Centocor Inc | IL-13 MUTEIN PROTEINS, ANTIBODIES, COMPOSITIONS, METHODS AND USES |
| US7619070B2 (en) * | 2003-04-23 | 2009-11-17 | Medarex, Inc. | Humanized antibodies to interferon alpha receptor-1 (IFNAR-1) |
| GB0407315D0 (en) | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| DK2805728T3 (da) | 2003-12-23 | 2020-04-20 | Genentech Inc | Hidtil ukendte anti-IL13-antistoffer og anvendelser deraf |
| CA2555841A1 (en) | 2004-02-12 | 2005-09-01 | Nektar Therapeutics | Interleukin-13 antagonist powders, spray-dried particles, and methods |
| US7501121B2 (en) | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| US20070048785A1 (en) | 2004-06-09 | 2007-03-01 | Lin Laura L | Anti-IL-13 antibodies and complexes |
| AR049390A1 (es) | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| WO2006055638A2 (en) | 2004-11-17 | 2006-05-26 | Abgenix, Inc. | Fully human monoclonal antibodies to il-13 |
| MY144906A (en) | 2005-10-21 | 2011-11-30 | Novartis Ag | Human antibodies against il13 and therapeutic uses |
| KR101544108B1 (ko) * | 2006-09-08 | 2015-08-13 | 애브비 바하마스 리미티드 | 인터루킨-13 결합 단백질 |
| ES2410886T3 (es) | 2006-10-26 | 2013-07-03 | Janssen Biotech, Inc. | Métodos para la adaptación al ser humano de anticuerpos monoclonales |
| BRPI0720280A2 (pt) * | 2006-12-11 | 2014-01-28 | Wyeth Corp | Métodos e composições para tratar e monitorar tratamento de desordens associadas à il-13 |
| ES2564523T3 (es) | 2007-12-19 | 2016-03-23 | Janssen Biotech, Inc. | Diseño y generación de bibliotecas de presentación en fago por pIX de novo humanas mediante fusión con pIX o pVII, vectores, anticuerpos y métodos |
| AU2009283008A1 (en) * | 2008-08-20 | 2010-02-25 | Centocor Ortho Biotech Inc. | Engineered anti-IL-13 antibodies, compositions, methods and uses |
-
2009
- 2009-08-11 AU AU2009283008A patent/AU2009283008A1/en not_active Abandoned
- 2009-08-11 NZ NZ591098A patent/NZ591098A/xx not_active IP Right Cessation
- 2009-08-11 US US13/058,453 patent/US8399630B2/en not_active Expired - Fee Related
- 2009-08-11 KR KR1020117006418A patent/KR20110043786A/ko not_active Withdrawn
- 2009-08-11 EA EA201170357A patent/EA201170357A1/ru unknown
- 2009-08-11 BR BRPI0917370A patent/BRPI0917370A2/pt not_active Application Discontinuation
- 2009-08-11 CA CA2734645A patent/CA2734645A1/en not_active Abandoned
- 2009-08-11 MX MX2011001909A patent/MX2011001909A/es not_active Application Discontinuation
- 2009-08-11 JP JP2011523864A patent/JP2012506695A/ja active Pending
- 2009-08-11 CN CN2009801424060A patent/CN102264391A/zh active Pending
- 2009-08-11 WO PCT/US2009/053425 patent/WO2010021874A2/en not_active Ceased
- 2009-08-11 EP EP09808611A patent/EP2328615A2/en not_active Withdrawn
- 2009-08-12 US US12/539,630 patent/US8323646B2/en not_active Expired - Fee Related
- 2009-08-19 UY UY0001032060A patent/UY32060A/es unknown
- 2009-08-19 AR ARP090103185A patent/AR073088A1/es unknown
-
2011
- 2011-02-06 IL IL211087A patent/IL211087A0/en unknown
- 2011-02-17 CO CO11019113A patent/CO6341573A2/es not_active Application Discontinuation
- 2011-02-18 NI NI201100040A patent/NI201100040A/es unknown
- 2011-02-18 EC EC2011010840A patent/ECSP11010840A/es unknown
- 2011-03-18 ZA ZA2011/02081A patent/ZA201102081B/en unknown
- 2011-03-21 CR CR20110152A patent/CR20110152A/es unknown
-
2012
- 2012-08-21 JP JP2012182330A patent/JP2013005805A/ja active Pending
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