JP2012179058A5 - - Google Patents
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- JP2012179058A5 JP2012179058A5 JP2012116438A JP2012116438A JP2012179058A5 JP 2012179058 A5 JP2012179058 A5 JP 2012179058A5 JP 2012116438 A JP2012116438 A JP 2012116438A JP 2012116438 A JP2012116438 A JP 2012116438A JP 2012179058 A5 JP2012179058 A5 JP 2012179058A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2002123534 DE10223534A1 (de) | 2002-05-27 | 2002-05-27 | Verwendung von Adenoviren und dafür codierenden Nukleinsäuren |
DE10223534.1 | 2002-05-27 | ||
DE10225400 | 2002-06-07 | ||
DE10225400.1 | 2002-06-07 | ||
DE10248039 | 2002-10-15 | ||
DE10248039.7 | 2002-10-15 | ||
DE10322530.7 | 2003-05-19 | ||
DE10322530 | 2003-05-19 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004508113A Division JP5213298B2 (ja) | 2002-05-27 | 2003-05-27 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014158673A Division JP2014224141A (ja) | 2002-05-27 | 2014-08-04 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2012179058A JP2012179058A (ja) | 2012-09-20 |
JP2012179058A5 true JP2012179058A5 (ja) | 2013-01-24 |
JP5719800B2 JP5719800B2 (ja) | 2015-05-20 |
Family
ID=29587746
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004508113A Expired - Lifetime JP5213298B2 (ja) | 2002-05-27 | 2003-05-27 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
JP2012116438A Expired - Lifetime JP5719800B2 (ja) | 2002-05-27 | 2012-05-22 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
JP2014158673A Withdrawn JP2014224141A (ja) | 2002-05-27 | 2014-08-04 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004508113A Expired - Lifetime JP5213298B2 (ja) | 2002-05-27 | 2003-05-27 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014158673A Withdrawn JP2014224141A (ja) | 2002-05-27 | 2014-08-04 | アデノウイルスおよびそれをコードしている核酸の新たな使用 |
Country Status (9)
Country | Link |
---|---|
US (5) | US20060099178A1 (ja) |
EP (1) | EP1506021B1 (ja) |
JP (3) | JP5213298B2 (ja) |
KR (1) | KR101083450B1 (ja) |
CN (2) | CN1655827B (ja) |
AU (2) | AU2003242585A1 (ja) |
CA (1) | CA2487811A1 (ja) |
WO (1) | WO2003099859A2 (ja) |
ZA (1) | ZA200409361B (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003099859A2 (de) | 2002-05-27 | 2003-12-04 | Per Sonne Holm | Neue verwendung von adenoviren und dafür codierenden nukleinsäuren |
EP1689446B1 (de) * | 2003-11-14 | 2015-01-07 | Per Sonne Holm | Neue adenoviren, dafür codierende nukleinsäuren und deren verwendung |
WO2005051430A1 (de) * | 2003-11-14 | 2005-06-09 | Per Sonne Holm | Neue verwendung von adenoviren und dafür codierenden nukleinsäuren |
US8361976B2 (en) | 2004-07-09 | 2013-01-29 | University Of Massachusetts | Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules |
AU2006203736B2 (en) * | 2004-12-31 | 2012-03-29 | Per Sonne Holm | Method for reversing multiple resistance in animal cells |
WO2006070024A2 (de) * | 2004-12-31 | 2006-07-06 | Per Sonne Holm | E1 -minus adenoviren und deren verwendung |
WO2012022496A2 (en) | 2010-08-19 | 2012-02-23 | Per Sonne Holm | Method for killing tumor stem cells |
WO2014153204A1 (en) * | 2013-03-14 | 2014-09-25 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
JP7054527B2 (ja) | 2016-02-23 | 2022-04-14 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスの複製動態を測定するための高スループットアッセイ |
KR20180112024A (ko) | 2016-02-23 | 2018-10-11 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
CN110062630A (zh) | 2016-12-12 | 2019-07-26 | 萨克生物研究学院 | 肿瘤靶向合成腺病毒及其用途 |
FI3762004T3 (fi) * | 2018-03-05 | 2023-12-11 | Klinikum Rechts Der Isar Der Technischen Univ Muenchen | Kasvainten hoitaminen onkolyyttisen adenoviruksen ja CDK4/6-inhibiittorin yhdistelmällä |
CA3104948A1 (en) * | 2018-06-25 | 2020-01-02 | Ospedale San Raffaele S.R.L | Gene therapy |
CN114615996A (zh) * | 2019-09-05 | 2022-06-10 | 慕尼黑工业大学临床教学中心 | 通过溶瘤腺病毒、cdk4/6抑制剂和其他治疗活性剂的组合治疗肿瘤 |
EP4123021A4 (en) * | 2020-03-23 | 2024-05-15 | Curigin Co.,Ltd. | STRUCTURE OF AN ONCOLYTIC VIRUS WITH BISPECIFIC NUCLEIC ACID MOLECULE |
CN114540349A (zh) * | 2020-11-27 | 2022-05-27 | 中国科学院分子细胞科学卓越创新中心 | 结合yb-1蛋白的核酸分子 |
EP4404947A1 (en) | 2021-09-23 | 2024-07-31 | Sagittarius Bio, Inc. | Adenoviruses and methods for using adenoviruses |
Family Cites Families (57)
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US931830A (en) * | 1907-09-17 | 1909-08-24 | Harry Zimmerman | Material-cutter. |
US4947842A (en) | 1988-09-22 | 1990-08-14 | Medical Engineering And Development Institute, Inc. | Method and apparatus for treating tissue with first and second modalities |
US5475096A (en) | 1990-06-11 | 1995-12-12 | University Research Corporation | Nucleic acid ligands |
CA2152941C (en) * | 1993-02-16 | 2003-04-22 | Francis Mccormick | Cytopathic viruses for therapy and prophylaxis of neoplasia |
US5846945A (en) * | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
US5698443A (en) | 1995-06-27 | 1997-12-16 | Calydon, Inc. | Tissue specific viral vectors |
CA2192442C (en) | 1994-06-10 | 2007-09-25 | Imre Kovesdi | Complementary adenoviral vector systems and cell lines |
US5998205A (en) | 1994-11-28 | 1999-12-07 | Genetic Therapy, Inc. | Vectors for tissue-specific replication |
US6326356B1 (en) * | 1996-10-18 | 2001-12-04 | Board Of Regents, The University Of Texas System | Suppression of neu overexpression using a mini-E1A gene |
US5707618A (en) | 1995-03-24 | 1998-01-13 | Genzyme Corporation | Adenovirus vectors for gene therapy |
DK0843731T3 (da) | 1995-03-24 | 2008-06-09 | Genzyme Corp | Adenovirusvektorer til genterapi |
US6676935B2 (en) | 1995-06-27 | 2004-01-13 | Cell Genesys, Inc. | Tissue specific adenoviral vectors |
AU7674896A (en) | 1995-10-31 | 1997-05-22 | Board Of Regents, The University Of Texas System | Adenovirus-antisense k-ras expression vectors and their application in cancer therapy |
US6022863A (en) | 1996-05-21 | 2000-02-08 | Yale University | Regulation of gene expression |
US6730662B1 (en) * | 1996-07-05 | 2004-05-04 | Mcgill University | Adenovirus E4 proteins for inducing cell death |
AU731924B2 (en) | 1996-07-05 | 2001-04-05 | Philip E. Branton | Adenovirus E4 proteins for inducing cell death |
ATE228529T1 (de) | 1996-08-30 | 2002-12-15 | Jens Peter Fuerste | Spiegelselektion und spiegelevolution von nucleinsäuren |
US5994132A (en) | 1996-10-23 | 1999-11-30 | University Of Michigan | Adenovirus vectors |
US6110744A (en) | 1996-11-13 | 2000-08-29 | Board Of Regents, The University Of Texas System | Diminishing viral gene expression by promoter replacement |
US6080578A (en) | 1996-12-31 | 2000-06-27 | Onyx Pharmaceuticals, Inc. | Cytopathic adenoviral E1B mutated viruses for therapy and prophylaxis of neoplasia |
US6100086A (en) | 1997-04-14 | 2000-08-08 | Genzyme Corporation | Transgene expression systems |
WO1999006576A1 (en) | 1997-08-04 | 1999-02-11 | Calydon, Inc. | A human glandular kallikrein enhancer, vectors comprising the enhancer and methods of use thereof |
DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
HUP0003911A3 (en) | 1997-10-09 | 2007-11-28 | Pro Virus | Treatment of neoplasms with viruses |
CN1110553C (zh) * | 1998-07-15 | 2003-06-04 | 杭州赛狮生物技术开发有限公司 | 基因工程腺病毒及其用途 |
US6649158B1 (en) | 1998-10-15 | 2003-11-18 | Canji, Inc. | Methods and compositions to induce antitumor response |
JP2002527455A (ja) | 1998-10-15 | 2002-08-27 | カンジ,インコーポレイテッド | 組換え欠失アデノウイルスベクター |
DE19860602A1 (de) | 1998-12-29 | 2000-07-06 | Max Delbrueck Centrum | Gentransfervektor für die Diagnostik und die Therapie von malignen Tumoren |
US6428968B1 (en) | 1999-03-15 | 2002-08-06 | The Trustees Of The University Of Pennsylvania | Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject |
GB9906815D0 (en) | 1999-03-24 | 1999-05-19 | Isrec | Anti-neoplastic viral agents |
DE19929569A1 (de) | 1999-06-21 | 2000-12-28 | Holm Per Sonne | Mittel zur Behandlung maligner Erkrankungen unter Verwendung des Proteins YB-1 |
WO2001002556A2 (de) | 1999-06-30 | 2001-01-11 | Max-Delbrück-Centrum für Molekulare Medizin | Mittel zur diagnose, prognose und therapie maligner erkrankungen |
US6955808B2 (en) | 1999-09-24 | 2005-10-18 | Uab Research Foundation | Capsid-modified recombinant adenovirus and methods of use |
AU1087701A (en) | 1999-10-15 | 2001-04-30 | Canji, Inc. | Targeted vectors |
US6140126A (en) | 1999-10-26 | 2000-10-31 | Isis Pharmaceuticals Inc. | Antisense modulation of Y-box binding protein 1 expression |
PT1230378E (pt) * | 1999-11-15 | 2007-09-17 | Onyx Pharma Inc | ''adenovírus oncolítico'' |
DE10015413A1 (de) | 2000-03-23 | 2001-09-27 | Max Delbrueck Centrum | Mittel zur Diagnose und Therapie viraler Erkrankungen |
JP2003534806A (ja) | 2000-05-31 | 2003-11-25 | ジェンベク、インコーポレイティッド | アデノウイルスベクターのターゲティングの方法および組成物 |
AU784975B2 (en) | 2000-10-11 | 2006-08-10 | Sumitomo Chemical Company, Limited | DNA-binding protein YB-1-containing collagen accumulation inhibitors |
WO2002042468A2 (en) | 2000-11-27 | 2002-05-30 | Geron Corporation | Glycosyltransferase vectors for treating cancer |
US20030095989A1 (en) | 2000-12-18 | 2003-05-22 | Irving John M. | Chimeric cytolytic viruses for cancer treatment |
CA2433071C (en) | 2000-12-28 | 2011-02-15 | Per Sonne Holm | Use of transcription factor yb-1 in adenoviral systems |
DE10150945A1 (de) | 2001-10-16 | 2003-04-17 | Holm Per Sonne | Adenovirale Systeme und deren Anwendungen |
US20030138405A1 (en) | 2001-04-17 | 2003-07-24 | Juan Fueyo | Conditionally replicative adenovirus to target the Rb and Rb-related pathways |
JP3974894B2 (ja) | 2001-09-14 | 2007-09-12 | 財団法人新産業創造研究機構 | 腫瘍特異的プロモーターおよびその用途 |
DE10150984A1 (de) | 2001-10-16 | 2003-04-17 | Holm Per Sonne | Verwendung des adenoviralen E2-late-Promotors |
ATE405663T1 (de) | 2002-04-25 | 2008-09-15 | Crucell Holland Bv | Stabile adenovirale vektoren und methoden für deren vermehrung |
WO2003099859A2 (de) | 2002-05-27 | 2003-12-04 | Per Sonne Holm | Neue verwendung von adenoviren und dafür codierenden nukleinsäuren |
MXPA05004074A (es) | 2002-10-15 | 2005-09-20 | Sonne Holm Per | Nuevos adenovirus, acidos nucleicos que los codifican y su uso. |
JP4988199B2 (ja) | 2002-10-15 | 2012-08-01 | ホルム,ペル・ゾンネ | 新規アデノウイルス、それをコードする核酸及びその使用 |
JP2006520604A (ja) | 2003-03-19 | 2006-09-14 | アイソジェニス・インコーポレイテッド | CD8α鎖に基づき免疫原性が減少した遺伝子治療ベクター |
WO2005051430A1 (de) | 2003-11-14 | 2005-06-09 | Per Sonne Holm | Neue verwendung von adenoviren und dafür codierenden nukleinsäuren |
EP1689446B1 (de) * | 2003-11-14 | 2015-01-07 | Per Sonne Holm | Neue adenoviren, dafür codierende nukleinsäuren und deren verwendung |
JP4621743B2 (ja) | 2004-12-13 | 2011-01-26 | カンジ,インコーポレイテッド | 複製欠損アデノウイルスの産生のための細胞株 |
AU2006203736B2 (en) | 2004-12-31 | 2012-03-29 | Per Sonne Holm | Method for reversing multiple resistance in animal cells |
WO2006070024A2 (de) | 2004-12-31 | 2006-07-06 | Per Sonne Holm | E1 -minus adenoviren und deren verwendung |
WO2007103825A2 (en) | 2006-03-02 | 2007-09-13 | The Board Of Regents Of The University Of Texas System | Combination therapy with oncolytic adenovirus |
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2003
- 2003-05-27 WO PCT/EP2003/005583 patent/WO2003099859A2/de active Application Filing
- 2003-05-27 US US10/515,238 patent/US20060099178A1/en not_active Abandoned
- 2003-05-27 CN CN03812310XA patent/CN1655827B/zh not_active Expired - Fee Related
- 2003-05-27 KR KR1020047019231A patent/KR101083450B1/ko active IP Right Grant
- 2003-05-27 AU AU2003242585A patent/AU2003242585A1/en not_active Abandoned
- 2003-05-27 EP EP03755145.4A patent/EP1506021B1/de not_active Expired - Lifetime
- 2003-05-27 CA CA002487811A patent/CA2487811A1/en not_active Abandoned
- 2003-05-27 CN CN201010161559.4A patent/CN101843641B/zh not_active Expired - Fee Related
- 2003-05-27 JP JP2004508113A patent/JP5213298B2/ja not_active Expired - Lifetime
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2004
- 2004-11-22 ZA ZA2004/09361A patent/ZA200409361B/en unknown
-
2010
- 2010-04-28 US US12/769,435 patent/US10155930B2/en not_active Expired - Lifetime
- 2010-09-09 AU AU2010219364A patent/AU2010219364B2/en not_active Ceased
-
2012
- 2012-05-22 JP JP2012116438A patent/JP5719800B2/ja not_active Expired - Lifetime
-
2014
- 2014-08-04 JP JP2014158673A patent/JP2014224141A/ja not_active Withdrawn
-
2017
- 2017-03-07 US US15/452,470 patent/US10538744B2/en not_active Expired - Fee Related
-
2018
- 2018-10-31 US US16/176,461 patent/US10731136B2/en not_active Expired - Fee Related
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2019
- 2019-12-05 US US16/704,669 patent/US11268073B2/en not_active Expired - Lifetime