AU7674896A - Adenovirus-antisense k-ras expression vectors and their application in cancer therapy - Google Patents

Adenovirus-antisense k-ras expression vectors and their application in cancer therapy

Info

Publication number
AU7674896A
AU7674896A AU76748/96A AU7674896A AU7674896A AU 7674896 A AU7674896 A AU 7674896A AU 76748/96 A AU76748/96 A AU 76748/96A AU 7674896 A AU7674896 A AU 7674896A AU 7674896 A AU7674896 A AU 7674896A
Authority
AU
Australia
Prior art keywords
adenovirus
antisense
application
expression vectors
cancer therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU76748/96A
Inventor
Ramon Alemany
Tapas Mukhopadhyay
Jack A Roth
Wei-Wei Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of AU7674896A publication Critical patent/AU7674896A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU76748/96A 1995-10-31 1996-10-31 Adenovirus-antisense k-ras expression vectors and their application in cancer therapy Abandoned AU7674896A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55095995A 1995-10-31 1995-10-31
US550959 1995-10-31
PCT/US1996/017979 WO1997016547A1 (en) 1995-10-31 1996-10-31 ADENOVIRUS-ANTISENSE K-ras EXPRESSION VECTORS AND THEIR APPLICATION IN CANCER THERAPY

Publications (1)

Publication Number Publication Date
AU7674896A true AU7674896A (en) 1997-05-22

Family

ID=24199268

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76748/96A Abandoned AU7674896A (en) 1995-10-31 1996-10-31 Adenovirus-antisense k-ras expression vectors and their application in cancer therapy

Country Status (2)

Country Link
AU (1) AU7674896A (en)
WO (1) WO1997016547A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042137A2 (en) * 1998-02-19 1999-08-26 Peter Bromley Stress promoter control of therapeutic genes in gene therapy: compositions and methods
WO2001002556A2 (en) * 1999-06-30 2001-01-11 Max-Delbrück-Centrum für Molekulare Medizin Agents for the diagnosis, prognosis and treatment of malignant diseases
DE10015413A1 (en) * 2000-03-23 2001-09-27 Max Delbrueck Centrum Composition for treating and diagnosing viral infections, caused by adenovirus, comprises an agent that modifies function of YB-1 protein, and YB-1 specific antibodies
US20030082140A1 (en) * 2001-08-20 2003-05-01 Fisher Paul B. Combinatorial methods for inducing cancer cell death
DE10150984A1 (en) * 2001-10-16 2003-04-17 Holm Per Sonne Expressing foreign nucleic acids with the adenoviral E2 late promoter, useful in the treatment of tumors, comprises selective activation by Y-box-binding protein-1 in tumor cell nuclei
US20060099178A1 (en) 2002-05-27 2006-05-11 Holm Per S Novel use of adenoviruses and nucleic acids coding therefor
WO2005051430A1 (en) 2003-11-14 2005-06-09 Per Sonne Holm Novel use of adenoviruses and nucleic acids that code for said viruses
US20070113295A1 (en) * 2005-09-23 2007-05-17 California Institute Of Technology Gene blocking method
CA3214540A1 (en) * 2021-04-22 2022-10-27 Pasi A. Janne Compositions and methods for treating cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2108144A1 (en) * 1991-03-06 1992-09-07 Jack A. Roth Methods and compositions for the selective inhibition of gene expression
DK0667912T3 (en) * 1993-07-13 2008-11-10 Centelion Defective adenovirus vectors and their use in gene therapy

Also Published As

Publication number Publication date
WO1997016547A1 (en) 1997-05-09

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