JP2012139224A5 - - Google Patents
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- JP2012139224A5 JP2012139224A5 JP2012032142A JP2012032142A JP2012139224A5 JP 2012139224 A5 JP2012139224 A5 JP 2012139224A5 JP 2012032142 A JP2012032142 A JP 2012032142A JP 2012032142 A JP2012032142 A JP 2012032142A JP 2012139224 A5 JP2012139224 A5 JP 2012139224A5
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- amino acid
- antigen
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 32
- 239000000427 antigen Substances 0.000 claims 32
- 102000036639 antigens Human genes 0.000 claims 32
- 108091007433 antigens Proteins 0.000 claims 32
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- 102000043959 human IL18 Human genes 0.000 claims 20
- 230000000694 effects Effects 0.000 claims 13
- 238000000034 method Methods 0.000 claims 13
- 238000006467 substitution reaction Methods 0.000 claims 13
- 102000003810 Interleukin-18 Human genes 0.000 claims 10
- 108090000171 Interleukin-18 Proteins 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 208000019693 Lung disease Diseases 0.000 claims 9
- 201000010099 disease Diseases 0.000 claims 8
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 7
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 6
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- QJJXYPPXXYFBGM-SHYZHZOCSA-N tacrolimus Natural products CO[C@H]1C[C@H](CC[C@@H]1O)C=C(C)[C@H]2OC(=O)[C@H]3CCCCN3C(=O)C(=O)[C@@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@@H](C[C@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC QJJXYPPXXYFBGM-SHYZHZOCSA-N 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- CJIJXIFQYOPWTF-UHFFFAOYSA-N 7-hydroxycoumarin Natural products O1C(=O)C=CC2=CC(O)=CC=C21 CJIJXIFQYOPWTF-UHFFFAOYSA-N 0.000 claims 1
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- XPDXVDYUQZHFPV-UHFFFAOYSA-N Dansyl Chloride Chemical compound C1=CC=C2C(N(C)C)=CC=CC2=C1S(Cl)(=O)=O XPDXVDYUQZHFPV-UHFFFAOYSA-N 0.000 claims 1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18160800P | 2000-02-10 | 2000-02-10 | |
| US60/181,608 | 2000-02-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001558102A Division JP2004500086A (ja) | 2000-02-10 | 2001-02-09 | ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012139224A JP2012139224A (ja) | 2012-07-26 |
| JP2012139224A5 true JP2012139224A5 (cg-RX-API-DMAC7.html) | 2013-04-25 |
Family
ID=22665007
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001558102A Pending JP2004500086A (ja) | 2000-02-10 | 2001-02-09 | ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法 |
| JP2012032142A Pending JP2012139224A (ja) | 2000-02-10 | 2012-02-16 | ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001558102A Pending JP2004500086A (ja) | 2000-02-10 | 2001-02-09 | ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法 |
Country Status (22)
Families Citing this family (183)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6608182B1 (en) | 1994-03-08 | 2003-08-19 | Human Genome Sciences, Inc. | Human vascular endothelial growth factor 2 |
| US7109308B1 (en) | 1994-03-08 | 2006-09-19 | Human Genome Sciences, Inc. | Antibodies to human vascular endothelial growth factor 2 |
| US6040157A (en) | 1994-03-08 | 2000-03-21 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| US7153827B1 (en) | 1994-03-08 | 2006-12-26 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 and methods of use |
| CA2414016A1 (en) | 1994-03-08 | 1995-09-14 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| US5932540A (en) | 1994-03-08 | 1999-08-03 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| US7186688B1 (en) | 1994-03-08 | 2007-03-06 | Human Genome Sciences, Inc. | Methods of stimulating angiogenesis in a patient by administering vascular endothelial growth factor 2 |
| US7223724B1 (en) | 1999-02-08 | 2007-05-29 | Human Genome Sciences, Inc. | Use of vascular endothelial growth factor to treat photoreceptor cells |
| EP1257585A2 (en) * | 2000-02-10 | 2002-11-20 | Basf Aktiengesellschaft | Antibodies that bind human interleukin-18 and methods of making and using |
| TR200502508T2 (tr) * | 2000-02-21 | 2007-04-24 | Applied Research Systems Ar� Holding N.V. | IL-18 İnhibitörlerinin kullanımı. |
| US20020025317A1 (en) * | 2000-07-20 | 2002-02-28 | Schering Ag | Bispecific monoclonal antibodies to IL-12 and IL-18 |
| AU8473401A (en) | 2000-08-04 | 2002-02-18 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| KR100857376B1 (ko) * | 2001-01-29 | 2008-09-05 | 라보라토리스 세로노 에스.에이. | 심장 질환의 치료 및/또는 예방에 사용되는 ｉｌ-18저해물질 |
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- 2012-02-16 JP JP2012032142A patent/JP2012139224A/ja active Pending
- 2012-04-25 CL CL2012001063A patent/CL2012001063A1/es unknown
- 2012-09-05 US US13/603,968 patent/US20130101595A1/en not_active Abandoned
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