JP2012135301A5 - - Google Patents

Info

Publication number

JP2012135301A5

JP2012135301A5 JP2011256511A JP2011256511A JP2012135301A5 JP 2012135301 A5 JP2012135301 A5 JP 2012135301A5 JP 2011256511 A JP2011256511 A JP 2011256511A JP 2011256511 A JP2011256511 A JP 2011256511A JP 2012135301 A5 JP2012135301 A5 JP 2012135301A5

Authority

JP

Japan

Prior art keywords

seq

polypeptide

sequence

bladder cancer

expression level

Prior art date

2011-11-24

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Links

• Espacenet
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• 108090000623 proteins and genes Proteins 0.000 claims description 19
• 230000014509 gene expression Effects 0.000 claims description 15
• 239000002773 nucleotide Substances 0.000 claims description 14
• 125000003729 nucleotide group Chemical group 0.000 claims description 14
• 102000004169 proteins and genes Human genes 0.000 claims description 5
• 108020004999 messenger RNA Proteins 0.000 claims description 4
• 230000027455 binding Effects 0.000 claims description 2
• 229920001184 polypeptide Polymers 0.000 claims 19
• 102000004196 processed proteins & peptides Human genes 0.000 claims 19
• 108090000765 processed proteins & peptides Proteins 0.000 claims 19
• 238000000034 method Methods 0.000 claims 17
• 206010005003 Bladder cancer Diseases 0.000 claims 16
• 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 16
• 150000001875 compounds Chemical class 0.000 claims 16
• 201000005112 urinary bladder cancer Diseases 0.000 claims 16
• 210000004027 cell Anatomy 0.000 claims 15
• 108091028664 Ribonucleotide Proteins 0.000 claims 9
• 108091081021 Sense strand Proteins 0.000 claims 9
• 125000003275 alpha amino acid group Chemical group 0.000 claims 9
• 108091033319 polynucleotide Proteins 0.000 claims 9
• 239000002157 polynucleotide Substances 0.000 claims 9
• 102000040430 polynucleotide Human genes 0.000 claims 9
• 239000002336 ribonucleotide Substances 0.000 claims 9
• 125000002652 ribonucleotide group Chemical group 0.000 claims 9
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 7
• 230000000692 anti-sense effect Effects 0.000 claims 7
• 230000000694 effects Effects 0.000 claims 7
• 108700008625 Reporter Genes Proteins 0.000 claims 4
• 239000012472 biological sample Substances 0.000 claims 4
• 230000004663 cell proliferation Effects 0.000 claims 4
• 238000012216 screening Methods 0.000 claims 4
• 108020004459 Small interfering RNA Proteins 0.000 claims 3
• 230000000295 complement effect Effects 0.000 claims 3
• 230000002062 proliferating effect Effects 0.000 claims 3
• 239000000523 sample Substances 0.000 claims 3
• 239000000032 diagnostic agent Substances 0.000 claims 2
• 229940039227 diagnostic agent Drugs 0.000 claims 2
• 210000002919 epithelial cell Anatomy 0.000 claims 2
• 230000001105 regulatory effect Effects 0.000 claims 2
• 239000004055 small Interfering RNA Substances 0.000 claims 2
• 230000002103 transcriptional effect Effects 0.000 claims 2
• 108020004414 DNA Proteins 0.000 claims 1
• 108091034117 Oligonucleotide Proteins 0.000 claims 1
• 239000004480 active ingredient Substances 0.000 claims 1
• 230000004071 biological effect Effects 0.000 claims 1
• 239000003153 chemical reaction reagent Substances 0.000 claims 1
• 239000003795 chemical substances by application Substances 0.000 claims 1
• 230000007423 decrease Effects 0.000 claims 1
• 238000001514 detection method Methods 0.000 claims 1
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• 108020000948 Antisense Oligonucleotides Proteins 0.000 description 2
• 239000000074 antisense oligonucleotide Substances 0.000 description 2
• 238000012230 antisense oligonucleotides Methods 0.000 description 2
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