JP2012067110A5 - - Google Patents
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- Publication number
- JP2012067110A5 JP2012067110A5 JP2011233850A JP2011233850A JP2012067110A5 JP 2012067110 A5 JP2012067110 A5 JP 2012067110A5 JP 2011233850 A JP2011233850 A JP 2011233850A JP 2011233850 A JP2011233850 A JP 2011233850A JP 2012067110 A5 JP2012067110 A5 JP 2012067110A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- chlorite
- disorder
- tcdo
- matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 claims 10
- 229910001919 chlorite Inorganic materials 0.000 claims 8
- 229910052619 chlorite group Inorganic materials 0.000 claims 8
- VOWOEBADKMXUBU-UHFFFAOYSA-J molecular oxygen;tetrachlorite;hydrate Chemical compound O.O=O.[O-]Cl=O.[O-]Cl=O.[O-]Cl=O.[O-]Cl=O VOWOEBADKMXUBU-UHFFFAOYSA-J 0.000 claims 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 208000035475 disorder Diseases 0.000 claims 6
- 208000024827 Alzheimer disease Diseases 0.000 claims 4
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 4
- 239000013011 aqueous formulation Substances 0.000 claims 4
- -1 chlorite ions Chemical class 0.000 claims 4
- 229940077239 chlorous acid Drugs 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 201000006417 multiple sclerosis Diseases 0.000 claims 4
- 210000002540 macrophage Anatomy 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 208000015122 neurodegenerative disease Diseases 0.000 claims 2
- UKLNMMHNWFDKNT-UHFFFAOYSA-M sodium chlorite Chemical group [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 claims 2
- 229960002218 sodium chlorite Drugs 0.000 claims 2
- 230000001575 pathological effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54157604P | 2004-02-03 | 2004-02-03 | |
| US60/541,576 | 2004-02-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552151A Division JP5072367B2 (ja) | 2004-02-03 | 2005-01-25 | 神経変性疾患の処置における亜塩素酸 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015118841A Division JP2015205901A (ja) | 2004-02-03 | 2015-06-12 | 神経変性疾患の処置における亜塩素酸 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012067110A JP2012067110A (ja) | 2012-04-05 |
| JP2012067110A5 true JP2012067110A5 (enExample) | 2013-04-04 |
| JP5797083B2 JP5797083B2 (ja) | 2015-10-21 |
Family
ID=34860199
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552151A Expired - Lifetime JP5072367B2 (ja) | 2004-02-03 | 2005-01-25 | 神経変性疾患の処置における亜塩素酸 |
| JP2011233850A Expired - Lifetime JP5797083B2 (ja) | 2004-02-03 | 2011-10-25 | 神経変性疾患の処置における亜塩素酸 |
| JP2015118841A Pending JP2015205901A (ja) | 2004-02-03 | 2015-06-12 | 神経変性疾患の処置における亜塩素酸 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552151A Expired - Lifetime JP5072367B2 (ja) | 2004-02-03 | 2005-01-25 | 神経変性疾患の処置における亜塩素酸 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015118841A Pending JP2015205901A (ja) | 2004-02-03 | 2015-06-12 | 神経変性疾患の処置における亜塩素酸 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US7105183B2 (enExample) |
| EP (2) | EP2574342B1 (enExample) |
| JP (3) | JP5072367B2 (enExample) |
| CN (2) | CN102423318B (enExample) |
| AU (1) | AU2005213300B2 (enExample) |
| CA (2) | CA2838392C (enExample) |
| WO (1) | WO2005076819A2 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7273888B2 (en) * | 2001-11-16 | 2007-09-25 | Als Therapy Development Foundation, Inc. | Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis |
| US7105183B2 (en) | 2004-02-03 | 2006-09-12 | The Regents Of The University Of California | Chlorite in the treatment of neurodegenerative disease |
| WO2006009505A1 (en) * | 2004-07-16 | 2006-01-26 | Gyros Patent Ab | Grading of immune responses |
| US8841076B2 (en) | 2005-05-09 | 2014-09-23 | Theranos, Inc. | Systems and methods for conducting animal studies |
| CN109187944A (zh) * | 2005-08-02 | 2019-01-11 | 埃克斯生物科技公司 | 使用IL-1α自身抗体诊断、治疗和预防血管疾病 |
| AU2013234421B2 (en) * | 2005-12-22 | 2015-08-27 | Neuraltus Pharmaceuticals, Inc. | Chlorite formulations, and methods of preparation and use thereof |
| US8067035B2 (en) * | 2005-12-22 | 2011-11-29 | Neuraltus Pharmaceuticals, Inc. | Chlorite formulations, and methods of preparation and use thereof |
| US8741230B2 (en) | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
| US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
| US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
| US20110008282A1 (en) * | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
| PT2109623E (pt) * | 2006-05-22 | 2012-01-12 | Xbiotech Inc | Tratamento de cancro com anticorpos anti-il-1 |
| US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
| FR2910811B1 (fr) * | 2007-01-03 | 2009-07-10 | Ass Pour Le Dev De La Biothera | Utilisation du riluzole et de ses derives pour fabriquer de nouveaux medicaments |
| US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
| CN105467136B (zh) * | 2008-05-30 | 2018-02-16 | 埃克斯生物科技公司 | 白细胞介素‑1α抗体及使用方法 |
| WO2010030979A2 (en) * | 2008-09-12 | 2010-03-18 | Xbiotech, Inc. | Targeting pathogenic monocytes |
| CN102573500A (zh) * | 2009-08-06 | 2012-07-11 | 纽拉尔图斯制药公司 | 巨噬细胞相关疾病的治疗 |
| KR20180078345A (ko) | 2009-10-19 | 2018-07-09 | 테라노스, 인코포레이티드 | 통합형 건강 정보 취득 및 분석 시스템 |
| CA2792471A1 (en) * | 2010-03-10 | 2011-09-15 | Yeda Research And Development Co. Ltd | Cellular blood markers for early diagnosis of als and for als progression |
| JP6324720B2 (ja) | 2010-06-18 | 2018-05-16 | エックスバイオテク, インコーポレイテッドXbiotech, Inc. | 関節炎治療 |
| CA2808307C (en) * | 2010-08-16 | 2022-06-21 | Allergan, Inc. | Method of activating regulatory t cells with alpha-2b adrenergic receptor agonists |
| KR102748255B1 (ko) | 2010-08-23 | 2024-12-31 | 엑스바이오테크 인코포레이티드 | 종양성 질병들에 대한 치료 |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| JP6204915B2 (ja) | 2011-09-23 | 2017-09-27 | エックスバイオテク, インコーポレイテッドXbiotech, Inc. | 悪液質治療 |
| CA2857604A1 (en) | 2011-12-22 | 2013-06-27 | Nuvo Research Gmbh | Liposomal chlorite or chlorate compositions |
| EP2890398A4 (en) | 2012-08-31 | 2016-03-09 | Five Prime Therapeutics Inc | METHODS OF TREATING DISEASES WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR RECEIVER 1 (CSF1R) |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| JP2017518265A (ja) * | 2014-05-16 | 2017-07-06 | ニューラルタス ファーマシューティカルズ，インク． | マクロファージ関連疾患の処置のための方法と組成物 |
| EP3072513A1 (en) * | 2015-03-26 | 2016-09-28 | Medday | Biotin for treating Amyotrophic lateral sclerosis |
| WO2017079161A2 (en) | 2015-11-02 | 2017-05-11 | Neuraltus Pharmaceuticals, Inc. | Treatment of neurodegenerative disease with sodium chlorite |
| KR20190117579A (ko) | 2017-02-16 | 2019-10-16 | 엑스바이오테크, 인크. | 화농성 한선염의 치료 |
| JP2024533873A (ja) | 2021-10-04 | 2024-09-12 | ニューヴィヴォ， インコーポレイテッド | Ａｌｓ患者の処置方法 |
| CA3253808A1 (en) * | 2022-05-19 | 2023-11-23 | Neuvivo Inc | BIOMARKERS OF NEURODEGENERATIVE DISEASES |
| US20250114396A1 (en) * | 2023-07-07 | 2025-04-10 | The Regents Of The University Of California | Chlorite uses for stem cells |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3213389A1 (de) * | 1982-04-10 | 1983-10-20 | Friedrich-Wilhelm Dr. 7107 Neckarsulm Kühne | Stabilisierter aktivierter sauerstoff und arzneimittel, die diesen stabilisierten aktivierten sauerstoff enthalten |
| US4576945A (en) * | 1982-10-26 | 1986-03-18 | Sanders Mark E | Hexaalkylmelamine-amino-oxy compounds |
| DE3515745A1 (de) | 1985-05-02 | 1986-11-06 | Oxo Chemie GmbH, 6900 Heidelberg | Waessrige chloritmatrix-loesung |
| US5051414A (en) * | 1989-08-03 | 1991-09-24 | Dupont Merck Pharmaceutical Company | Inhibition of HIV and other retroviruses by polyoxoanions |
| DE4208828A1 (de) | 1992-03-19 | 1993-09-23 | Oxo Chemie Gmbh | Verwendung einer chemisch stabilisierten chloritmatrix zur herstellung von arzneimitteln zur behandlung von hiv-infektionen |
| US6099855A (en) * | 1992-06-25 | 2000-08-08 | Bioxy, Inc. | Therapeutic, production and immunostimulatory uses of biocidal compositions |
| US5855922A (en) * | 1995-12-07 | 1999-01-05 | Bio-Cide International, Inc. | Antiseptic composition and process for prophylaxis and therapeutic treatment of dermal disorders |
| US5877222A (en) | 1996-07-19 | 1999-03-02 | The Regents Of The University Of California | Method for treating aids-associated dementia |
| ES2217582T3 (es) | 1997-10-06 | 2004-11-01 | Oxo Chemie Ag | Uso de una disolucion de clorito quimicamente estabilizada para inhibir una respuesta inmunitaria especifica de un antigeno. |
| US7087648B1 (en) | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
| JP2001078775A (ja) * | 1999-09-14 | 2001-03-27 | Kokuritsu Seishin Shinkei Center | マクロファージ機能調節剤 |
| CN1433481A (zh) * | 1999-11-30 | 2003-07-30 | 奥克索化学有限公司 | 通过基因表达分析评价和预测临术预后 |
| US6685754B2 (en) | 2001-03-06 | 2004-02-03 | Alchemix Corporation | Method for the production of hydrogen-containing gaseous mixtures |
| US7273888B2 (en) * | 2001-11-16 | 2007-09-25 | Als Therapy Development Foundation, Inc. | Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis |
| US7105183B2 (en) * | 2004-02-03 | 2006-09-12 | The Regents Of The University Of California | Chlorite in the treatment of neurodegenerative disease |
-
2005
- 2005-01-24 US US11/042,816 patent/US7105183B2/en not_active Expired - Lifetime
- 2005-01-25 EP EP12192303.1A patent/EP2574342B1/en not_active Expired - Lifetime
- 2005-01-25 JP JP2006552151A patent/JP5072367B2/ja not_active Expired - Lifetime
- 2005-01-25 WO PCT/US2005/002469 patent/WO2005076819A2/en not_active Ceased
- 2005-01-25 CN CN201110317862.3A patent/CN102423318B/zh not_active Expired - Lifetime
- 2005-01-25 EP EP05722556.7A patent/EP1711191B1/en not_active Expired - Lifetime
- 2005-01-25 CA CA2838392A patent/CA2838392C/en not_active Expired - Lifetime
- 2005-01-25 CA CA2554511A patent/CA2554511C/en not_active Expired - Lifetime
- 2005-01-25 CN CN2005800037236A patent/CN101102781B/zh not_active Expired - Lifetime
- 2005-01-25 AU AU2005213300A patent/AU2005213300B2/en not_active Expired
-
2006
- 2006-03-17 US US11/378,987 patent/US8029826B2/en active Active
-
2010
- 2010-10-07 US US12/900,361 patent/US20110053186A1/en not_active Abandoned
-
2011
- 2011-10-25 JP JP2011233850A patent/JP5797083B2/ja not_active Expired - Lifetime
-
2012
- 2012-04-27 US US13/458,954 patent/US9364501B2/en not_active Expired - Lifetime
-
2015
- 2015-06-12 JP JP2015118841A patent/JP2015205901A/ja active Pending
-
2016
- 2016-09-12 US US15/262,981 patent/US20170065634A1/en not_active Abandoned
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