BR112015025675A2 - derivados do tipo bisamida de ácido dicarboxílico, uso dos mesmos, composição farmacêutica à base dos mesmos, e métodos para produzir derivados do tipo bisamida de ácido dicarboxílico - Google Patents

derivados do tipo bisamida de ácido dicarboxílico, uso dos mesmos, composição farmacêutica à base dos mesmos, e métodos para produzir derivados do tipo bisamida de ácido dicarboxílico

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Publication number
BR112015025675A2
BR112015025675A2 BR112015025675A BR112015025675A BR112015025675A2 BR 112015025675 A2 BR112015025675 A2 BR 112015025675A2 BR 112015025675 A BR112015025675 A BR 112015025675A BR 112015025675 A BR112015025675 A BR 112015025675A BR 112015025675 A2 BR112015025675 A2 BR 112015025675A2
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BR
Brazil
Prior art keywords
dicarboxylic acid
bisamide
acid derivatives
derivatives
methods
Prior art date
Application number
BR112015025675A
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English (en)
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BR112015025675B1 (pt
BR112015025675A8 (pt
Inventor
Alexandrovna Zheltukhina Galina
Alexandrovna Kromova Tatyana
Evgenievich Nebolsin Vladimir
Original Assignee
Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
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Publication date
Application filed by Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises filed Critical Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
Publication of BR112015025675A2 publication Critical patent/BR112015025675A2/pt
Publication of BR112015025675A8 publication Critical patent/BR112015025675A8/pt
Publication of BR112015025675B1 publication Critical patent/BR112015025675B1/pt

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
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Abstract

resumo patente de invenção: "derivados do tipo bisamida de ácido dicarboxílico, uso dos mesmos, composição farmacêutica à base dos mesmos, e métodos para produzir derivados do tipo bisamida de ácido dicarboxílico". a presente invenção refere-se a novos compostos biologicamente ativos, em particular derivados do tipo bisamida de ácido dicarboxílico de fórmula geral i: , ou sais farmaceuticamente aceitáveis dos mesmos, que são capazes de formar complexos com íons metálicos ou quelatar íons metálicos. a invenção também se refere ao uso dos referidos compostos como um agente para a prevenção e/ou o tratamento de doenças cardiovasculares, virais, cancerosas, neurodegenerativas e inflamatórias, diabetes, doenças relacionadas com a idade, doenças causadas por toxinas microbianas, alcoolismo e cirrose alcoólica, anemia, porfiria cutânea tardia, e envenamento por sal de metal de transição. a presente invenção também se refere a novos métodos para preparar derivados do tipo bisamida de ácido dicarboxílico de fórmula geral i.
BR112015025675-9A 2013-04-12 2014-04-10 Derivados do tipo bisamida de ácido dicarboxílico, seu método de produção, seu uso e composição farmacêutica que os compreendem BR112015025675B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2013116822A RU2665688C2 (ru) 2013-04-12 2013-04-12 Производные бисамидов дикарбоновых кислот, их применение, фармацевтическая композиция на их основе, способы их получения
RU2013116822 2013-04-12
PCT/RU2014/000265 WO2014168523A1 (ru) 2013-04-12 2014-04-10 Производные бисамидов дикарбоновых кислот, их применение, фармацевтическая композиция на их основе, способы их получения

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BR112015025675A2 true BR112015025675A2 (pt) 2017-07-18
BR112015025675A8 BR112015025675A8 (pt) 2023-04-18
BR112015025675B1 BR112015025675B1 (pt) 2024-01-02

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US (3) US20160031858A1 (pt)
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CN (6) CN109096200B (pt)
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