JP2012041279A - 血圧低下作用を呈するカフェ酸誘導体の製造方法 - Google Patents
血圧低下作用を呈するカフェ酸誘導体の製造方法 Download PDFInfo
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- JP2012041279A JP2012041279A JP2010181497A JP2010181497A JP2012041279A JP 2012041279 A JP2012041279 A JP 2012041279A JP 2010181497 A JP2010181497 A JP 2010181497A JP 2010181497 A JP2010181497 A JP 2010181497A JP 2012041279 A JP2012041279 A JP 2012041279A
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- caffeic acid
- arginine
- acid derivative
- blood pressure
- water
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Landscapes
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Abstract
【解決手段】 目的とするカフェ酸誘導体はアルギニン、アラニンとフェニルアラニンからなるトリペプチド及び2分子のカフェ酸から構成される。カフェ酸はトリペプチドのアルギニンと結合し、カルシウム拮抗作用を呈する。この製造方法はヤーコンの粉末を水に懸濁し、分岐シクロデキストリンを添加してプロテアーゼ処理した後、濾過したろ液にアルギニンを添加してアルカリ還元する工程からなる。アルギニンとペプチドを分岐シクロデキストリンとアルカリ還元処理する工程により効率良く目的とするカフェ酸誘導体を得る。
【選択図】 なし
Description
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(試験例3)
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JP2010181497A JP5585958B2 (ja) | 2010-08-16 | 2010-08-16 | 血圧低下作用を呈するカフェ酸誘導体の製造方法 |
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JP2010181497A JP5585958B2 (ja) | 2010-08-16 | 2010-08-16 | 血圧低下作用を呈するカフェ酸誘導体の製造方法 |
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JP2003081824A (ja) * | 2001-09-06 | 2003-03-19 | Kao Corp | 高血圧症予防・改善・治療剤 |
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JP2001019664A (ja) * | 1999-07-06 | 2001-01-23 | Natl Food Res Inst | トリカフェオイルアルダル酸、その製造法及びその用途 |
JP2003081824A (ja) * | 2001-09-06 | 2003-03-19 | Kao Corp | 高血圧症予防・改善・治療剤 |
JP2004018395A (ja) * | 2002-06-12 | 2004-01-22 | Api Co Ltd | 血圧降下剤、その製造方法及びプロポリス組成物 |
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