JP2011529571A5 - - Google Patents
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- JP2011529571A5 JP2011529571A5 JP2011520526A JP2011520526A JP2011529571A5 JP 2011529571 A5 JP2011529571 A5 JP 2011529571A5 JP 2011520526 A JP2011520526 A JP 2011520526A JP 2011520526 A JP2011520526 A JP 2011520526A JP 2011529571 A5 JP2011529571 A5 JP 2011529571A5
- Authority
- JP
- Japan
- Prior art keywords
- amount
- biological sample
- nds
- mci
- normal control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8515408P | 2008-07-31 | 2008-07-31 | |
| US61/085,154 | 2008-07-31 | ||
| PCT/EP2009/059951 WO2010012828A2 (en) | 2008-07-31 | 2009-07-31 | Glutaminyl cyclase as a diagnostic / prognostic indicator for neurodegenerative diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011529571A JP2011529571A (ja) | 2011-12-08 |
| JP2011529571A5 true JP2011529571A5 (https=) | 2012-09-20 |
| JP5677297B2 JP5677297B2 (ja) | 2015-02-25 |
Family
ID=41256108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011520526A Active JP5677297B2 (ja) | 2008-07-31 | 2009-07-31 | 神経変性疾患の診断／予後判定の指標としてのグルタミニルシクラーゼ |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20100028918A1 (https=) |
| EP (1) | EP2329274B1 (https=) |
| JP (1) | JP5677297B2 (https=) |
| KR (1) | KR101682728B1 (https=) |
| CN (2) | CN103983787A (https=) |
| AU (1) | AU2009275869B2 (https=) |
| BR (1) | BRPI0916601B1 (https=) |
| CA (1) | CA2731933A1 (https=) |
| EA (1) | EA025107B1 (https=) |
| IL (1) | IL210266A (https=) |
| MX (1) | MX2011001093A (https=) |
| NZ (1) | NZ590658A (https=) |
| SG (1) | SG193148A1 (https=) |
| WO (1) | WO2010012828A2 (https=) |
| ZA (1) | ZA201100177B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011101433A1 (en) * | 2010-02-18 | 2011-08-25 | Probiodrug Ag | Methods of diagnosing inflammatory diseases by determining pyroglutamate-modified mcp-1 and screening methods for inhibitors of glutaminyl cyclase |
| SG194770A1 (en) | 2011-05-27 | 2013-12-30 | Probiodrug Ag | Radiolabelled glutaminyl cyclase inhibitors |
| JP2018501482A (ja) | 2014-12-19 | 2018-01-18 | プロビオドルグ エージー | ｐＧｌｕ−Ａｂｅｔａペプチドの検出のための新規の方法 |
| CN104946680A (zh) * | 2015-06-11 | 2015-09-30 | 深圳大学 | 用于表达qc的重组载体及其制备方法、引物、基因工程菌 |
| KR102362919B1 (ko) * | 2016-07-08 | 2022-02-16 | 아지노모토 가부시키가이샤 | 경도 인지 장해 또는 알츠하이머형 인지증의 평가 방법 |
| KR102858457B1 (ko) * | 2023-06-07 | 2025-09-11 | 계명대학교 산학협력단 | Ccl8 단백질 또는 이를 코딩하는 유전자를 유효성분으로 포함하는 퇴행성 뇌질환 진단용 바이오마커 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4374316B2 (ja) * | 1993-01-25 | 2009-12-02 | 武田薬品工業株式会社 | β−アミロイドまたはその誘導体に対する抗体およびその用途 |
| JP3590468B2 (ja) * | 1996-01-22 | 2004-11-17 | 財団法人 東京都医学研究機構 | アルツハイマー病診断薬 |
| WO2004013172A2 (en) * | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
| US7732162B2 (en) * | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| CN1784220B (zh) * | 2003-05-05 | 2011-08-03 | 前体生物药物股份公司 | 谷氨酰胺酰基和谷氨酸环化酶效应物的应用 |
| BRPI0415409A (pt) * | 2003-10-15 | 2006-12-05 | Probiodrug Ag | uso de efetuadores de ciclases de glutaminila e glutamato |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| CA2554809C (en) * | 2004-02-05 | 2014-04-29 | Probiodrug Ag | Novel n-alkyl thiourea- and thioamide-substituted imidazolyl inhibitors of glutaminyl cyclase |
| US7592467B2 (en) * | 2005-04-11 | 2009-09-22 | Probiodrug Ag | Inhibitors of prolyl endopeptidase |
| EP1865326B1 (en) * | 2006-06-08 | 2011-09-07 | FU Berlin | Assay for the diagnosis of Alzheimer's Disease based on the determination of the ratio of secretase Aß cleavage products |
| EA016584B1 (ru) * | 2006-09-21 | 2012-06-29 | Пробиодруг Аг | Новые гены, родственные гену глутаминилциклазы |
| WO2008087197A1 (en) * | 2007-01-19 | 2008-07-24 | Probiodrug Ag | In vivo screening models for treatment of alzheimer's disease and other qpct-related disorders |
-
2009
- 2009-07-31 US US12/533,099 patent/US20100028918A1/en not_active Abandoned
- 2009-07-31 KR KR1020117002132A patent/KR101682728B1/ko active Active
- 2009-07-31 WO PCT/EP2009/059951 patent/WO2010012828A2/en not_active Ceased
- 2009-07-31 SG SG2013056478A patent/SG193148A1/en unknown
- 2009-07-31 EP EP09781358.8A patent/EP2329274B1/en active Active
- 2009-07-31 CA CA2731933A patent/CA2731933A1/en not_active Abandoned
- 2009-07-31 NZ NZ590658A patent/NZ590658A/en unknown
- 2009-07-31 EA EA201100253A patent/EA025107B1/ru not_active IP Right Cessation
- 2009-07-31 BR BRPI0916601-7A patent/BRPI0916601B1/pt active IP Right Grant
- 2009-07-31 CN CN201410221835.XA patent/CN103983787A/zh active Pending
- 2009-07-31 CN CN200980130500.4A patent/CN102112880B/zh active Active
- 2009-07-31 AU AU2009275869A patent/AU2009275869B2/en active Active
- 2009-07-31 JP JP2011520526A patent/JP5677297B2/ja active Active
- 2009-07-31 MX MX2011001093A patent/MX2011001093A/es active IP Right Grant
-
2010
- 2010-12-26 IL IL210266A patent/IL210266A/en active IP Right Grant
-
2011
- 2011-01-06 ZA ZA2011/00177A patent/ZA201100177B/en unknown
-
2015
- 2015-03-12 US US14/645,821 patent/US20150247180A1/en not_active Abandoned
-
2016
- 2016-12-14 US US15/378,328 patent/US20170097365A1/en not_active Abandoned
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