JP2011524422A5 - - Google Patents
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- Publication number
- JP2011524422A5 JP2011524422A5 JP2011514764A JP2011514764A JP2011524422A5 JP 2011524422 A5 JP2011524422 A5 JP 2011524422A5 JP 2011514764 A JP2011514764 A JP 2011514764A JP 2011514764 A JP2011514764 A JP 2011514764A JP 2011524422 A5 JP2011524422 A5 JP 2011524422A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- methanone
- trimethoxyphenyl
- thiazol
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 CC[C@@](C)***(*(CC1)*C2C(*)CC(C)(*)C[C@@]1(*)*2)N Chemical compound CC[C@@](C)***(*(CC1)*C2C(*)CC(C)(*)C[C@@]1(*)*2)N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6187508P | 2008-06-16 | 2008-06-16 | |
| US61/061,875 | 2008-06-16 | ||
| PCT/US2009/047572 WO2010074776A2 (en) | 2008-06-16 | 2009-06-16 | Compounds for the treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012072925A Division JP2012162541A (ja) | 2008-06-16 | 2012-03-28 | 癌を処置するための化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011524422A JP2011524422A (ja) | 2011-09-01 |
| JP2011524422A5 true JP2011524422A5 (https=) | 2012-08-02 |
| JP5507552B2 JP5507552B2 (ja) | 2014-05-28 |
Family
ID=41448223
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011514764A Active JP5507552B2 (ja) | 2008-06-16 | 2009-06-16 | 癌を処置するための化合物 |
| JP2012072925A Pending JP2012162541A (ja) | 2008-06-16 | 2012-03-28 | 癌を処置するための化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012072925A Pending JP2012162541A (ja) | 2008-06-16 | 2012-03-28 | 癌を処置するための化合物 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8592465B2 (https=) |
| EP (3) | EP3289876B1 (https=) |
| JP (2) | JP5507552B2 (https=) |
| KR (4) | KR20170128623A (https=) |
| CN (2) | CN104610230A (https=) |
| AU (1) | AU2009330686B2 (https=) |
| CA (2) | CA2962524C (https=) |
| CY (2) | CY1119217T1 (https=) |
| DK (3) | DK2303021T3 (https=) |
| ES (3) | ES2715926T3 (https=) |
| HR (1) | HRP20221086T1 (https=) |
| HU (3) | HUE060249T2 (https=) |
| IL (2) | IL209995A (https=) |
| LT (3) | LT3289876T (https=) |
| MX (1) | MX2010014066A (https=) |
| PL (3) | PL2959900T3 (https=) |
| PT (3) | PT2959900T (https=) |
| RU (1) | RU2514427C2 (https=) |
| SI (1) | SI3289876T1 (https=) |
| TR (1) | TR201903981T4 (https=) |
| UA (1) | UA105005C2 (https=) |
| WO (1) | WO2010074776A2 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8822513B2 (en) | 2010-03-01 | 2014-09-02 | Gtx, Inc. | Compounds for treatment of cancer |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| MX2010014066A (es) | 2008-06-16 | 2011-06-01 | Univ Tennessee Res Foundation | Compuestos para el tratamiento del cancer. |
| US11084811B2 (en) | 2010-03-01 | 2021-08-10 | Oncternal Therapeutics, Inc. | Compounds for treatment of cancer |
| AU2015227531B2 (en) * | 2010-03-01 | 2017-03-02 | Oncternal Therapeutics, Inc. | Compounds for treatment of cancer |
| JP5879273B2 (ja) | 2010-03-01 | 2016-03-08 | ジーティーエックス・インコーポレイテッド | 癌を処置するための化合物 |
| JP5997156B2 (ja) * | 2010-08-24 | 2016-09-28 | ジーティーエックス・インコーポレイテッド | 癌の治療のための化合物 |
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| CN105163584B (zh) | 2013-03-05 | 2019-06-04 | 田纳西大学研究基金会 | 用于治疗癌症的化合物 |
| NZ631142A (en) | 2013-09-18 | 2016-03-31 | Axikin Pharmaceuticals Inc | Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors |
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| TWI703133B (zh) | 2014-12-23 | 2020-09-01 | 美商艾克斯基製藥公司 | ３,５-二胺基吡唑激酶抑制劑 |
| CA2976741C (en) | 2015-03-30 | 2023-01-17 | Mission Therapeutics Limited | 1-cyano-pyrrolidine compounds as usp30 inhibitors |
| CN107840842A (zh) | 2016-09-19 | 2018-03-27 | 北京天诚医药科技有限公司 | 炔代杂环化合物、其制备方法及其在医药学上的应用 |
| AU2018300150A1 (en) | 2017-07-11 | 2020-01-30 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| TWI795440B (zh) | 2017-09-15 | 2023-03-11 | 美商佛瑪治療公司 | 作為ＣＢＰ／ｐ３００抑制劑之四氫─咪唑並喹啉化合物 |
| CN108586443B (zh) * | 2018-01-31 | 2019-11-26 | 佳木斯大学附属第一医院 | 一种防治支气管肺癌的药物及其制备方法 |
| JPWO2019188456A1 (ja) * | 2018-03-26 | 2021-03-18 | 学校法人 川崎学園 | 新規抗腫瘍剤 |
| KR20210021982A (ko) * | 2018-05-15 | 2021-03-02 | 유니버시티 오브 테네시 리서치 파운데이션 | 췌장암 치료용 화합물 |
| MX2020012291A (es) | 2018-05-15 | 2021-03-25 | Univ Tennessee Res Found | Compuestos para el tratamiento de cancer de mama triple negativo y cancer de ovario. |
| US10870648B2 (en) | 2018-06-29 | 2020-12-22 | Forma Therapeutics, Inc. | Inhibiting CREB binding protein (CBP) |
| US12440481B2 (en) | 2019-01-10 | 2025-10-14 | Vertex Pharmaceuticals Incorporated | Esters and carbamates as modulators of sodium channels |
| WO2020146682A1 (en) | 2019-01-10 | 2020-07-16 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| WO2020190791A1 (en) | 2019-03-15 | 2020-09-24 | Forma Therapeutics, Inc. | Inhibiting cyclic amp-responsive element-binding protein (creb) |
| BR112022010924A2 (pt) | 2019-12-06 | 2022-09-06 | Vertex Pharma | Tetra-hidrofuranos substituídos como moduladores de canais de sódio |
| US11801243B2 (en) | 2020-09-23 | 2023-10-31 | Forma Therapeutics, Inc. | Bromodomain inhibitors for androgen receptor-driven cancers |
| US11795168B2 (en) | 2020-09-23 | 2023-10-24 | Forma Therapeutics, Inc. | Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP) |
| CN116745294A (zh) * | 2020-12-25 | 2023-09-12 | 南京明德新药研发有限公司 | 酰胺噁唑类化合物 |
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| CN113999149B (zh) * | 2021-11-15 | 2024-04-02 | 沈阳药科大学 | 一种基于l-半胱氨酸合成二芳基硫醚类化合物的制备方法 |
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| WO2023205463A1 (en) | 2022-04-22 | 2023-10-26 | Vertex Pharmaceuticals Incorporated | Heteroaryl compounds for the treatment of pain |
| CN119212696A (zh) * | 2022-04-28 | 2024-12-27 | 维鲁公司 | [2-(1h-吲哚-3-基)-1h-咪唑-4-基](3,4,5-三甲氧基)甲酮和其盐的多晶型物 |
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| WO2025212948A1 (en) * | 2024-04-04 | 2025-10-09 | University Of Iowa Research Foundation | Therapeutic compounds and methods |
| CN119409641A (zh) * | 2024-11-05 | 2025-02-11 | 杭州电子科技大学 | 一种磺酰基衍生物和用途 |
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| US8426418B2 (en) | 2010-08-27 | 2013-04-23 | CollabRx Inc. | Method to treat melanoma in BRAF inhibitor-resistant subjects |
| WO2012131909A1 (ja) | 2011-03-29 | 2012-10-04 | 三菱電機株式会社 | サーボ制御装置の異常診断装置および異常診断システム |
| WO2012135781A1 (en) | 2011-04-01 | 2012-10-04 | Genentech, Inc. | Combinations of akt inhibitor compounds and chemotherapeutic agents, and methods of use |
| HUE026323T2 (en) | 2011-04-07 | 2016-05-30 | Bayer Ip Gmbh | Imidazopyridazines as akt kinase inhibitors |
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