JP2011521968A - プリンpi3k阻害剤化合物および使用方法 - Google Patents

プリンpi3k阻害剤化合物および使用方法 Download PDF

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JP2011521968A
JP2011521968A JP2011511842A JP2011511842A JP2011521968A JP 2011521968 A JP2011521968 A JP 2011521968A JP 2011511842 A JP2011511842 A JP 2011511842A JP 2011511842 A JP2011511842 A JP 2011511842A JP 2011521968 A JP2011521968 A JP 2011521968A
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purin
morpholino
cancer
alkylene
heterocyclyl
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JP2011521968A5 (cg-RX-API-DMAC7.html
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ジョーゼット カスタネド,
イリーナ チャコーリー,
エイドリアン フォルクス,
ダニエル ピー. サザーリン,
ナン チ ワン,
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ジェネンテック, インコーポレイテッド
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011511842A 2008-05-30 2009-05-29 プリンpi3k阻害剤化合物および使用方法 Pending JP2011521968A (ja)

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US5755908P 2008-05-30 2008-05-30
US61/057,559 2008-05-30
PCT/US2009/045603 WO2009146406A1 (en) 2008-05-30 2009-05-29 Purine pi3k inhibitor compounds and methods of use

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JP2011521968A true JP2011521968A (ja) 2011-07-28
JP2011521968A5 JP2011521968A5 (cg-RX-API-DMAC7.html) 2012-07-12

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EP (1) EP2279188B1 (cg-RX-API-DMAC7.html)
JP (1) JP2011521968A (cg-RX-API-DMAC7.html)
KR (1) KR20110042153A (cg-RX-API-DMAC7.html)
CN (1) CN102105474B (cg-RX-API-DMAC7.html)
AU (1) AU2009251291B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0909614A2 (cg-RX-API-DMAC7.html)
CA (1) CA2721851A1 (cg-RX-API-DMAC7.html)
ES (1) ES2533788T3 (cg-RX-API-DMAC7.html)
IL (1) IL208838A0 (cg-RX-API-DMAC7.html)
MX (1) MX2010012583A (cg-RX-API-DMAC7.html)
RU (1) RU2509081C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009146406A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201007524B (cg-RX-API-DMAC7.html)

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JP2014530903A (ja) * 2011-10-28 2014-11-20 ノバルティスアーゲー 新規プリン誘導体および疾患の処置におけるその使用
WO2014185367A1 (ja) * 2013-05-13 2014-11-20 第一三共株式会社 モルホリノプリン誘導体の製造方法
JP2016517872A (ja) * 2013-05-02 2016-06-20 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Cb2受容体アゴニストとしてのプリン誘導体
JP2018510192A (ja) * 2015-04-02 2018-04-12 セロン ファーマ エス.アー.Celon Pharma S.A. 免疫もしくは炎症性の疾患またはがんの処置に有用な7−(モルホリン−4−イル)ピラゾール[1,5−a]ピリミジン誘導体
JP2018521111A (ja) * 2015-04-21 2018-08-02 ▲貴▼州百▲霊▼企▲業▼集▲団▼制▲薬▼股▲分▼有限公司Guizhou Bailing Enterprise Group Pharmaceutical Co.,Ltd. プリニル−n−ヒドロキシルピリミジンホルムアミド誘導体、並びにその調製方法および使用
JP2022552185A (ja) * 2019-10-09 2022-12-15 バイオクリスト ファーマスーティカルズ,インコーポレイテッド 経口補体因子d阻害剤

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JP5775171B2 (ja) * 2010-12-16 2015-09-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 三環系pi3k阻害剤化合物及びその使用方法
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Cited By (7)

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Publication number Priority date Publication date Assignee Title
JP2014530903A (ja) * 2011-10-28 2014-11-20 ノバルティスアーゲー 新規プリン誘導体および疾患の処置におけるその使用
JP2016517872A (ja) * 2013-05-02 2016-06-20 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Cb2受容体アゴニストとしてのプリン誘導体
WO2014185367A1 (ja) * 2013-05-13 2014-11-20 第一三共株式会社 モルホリノプリン誘導体の製造方法
JP2018510192A (ja) * 2015-04-02 2018-04-12 セロン ファーマ エス.アー.Celon Pharma S.A. 免疫もしくは炎症性の疾患またはがんの処置に有用な7−(モルホリン−4−イル)ピラゾール[1,5−a]ピリミジン誘導体
JP2018521111A (ja) * 2015-04-21 2018-08-02 ▲貴▼州百▲霊▼企▲業▼集▲団▼制▲薬▼股▲分▼有限公司Guizhou Bailing Enterprise Group Pharmaceutical Co.,Ltd. プリニル−n−ヒドロキシルピリミジンホルムアミド誘導体、並びにその調製方法および使用
JP2022552185A (ja) * 2019-10-09 2022-12-15 バイオクリスト ファーマスーティカルズ,インコーポレイテッド 経口補体因子d阻害剤
JP7630502B2 (ja) 2019-10-09 2025-02-17 バイオクリスト ファーマスーティカルズ,インコーポレイテッド 経口補体因子d阻害剤

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AU2009251291B2 (en) 2013-05-02
CN102105474A (zh) 2011-06-22
ES2533788T3 (es) 2015-04-14
ZA201007524B (en) 2012-01-25
BRPI0909614A2 (pt) 2015-09-22
EP2279188A1 (en) 2011-02-02
RU2509081C2 (ru) 2014-03-10
EP2279188B1 (en) 2015-01-28
CA2721851A1 (en) 2009-12-03
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