|
NL62140C
(https=)
*
|
1942-12-16 |
|
|
|
|
DE2104179C3
(de)
|
1971-01-29 |
1980-10-02 |
Knoll Ag, 6700 Ludwigshafen |
exo-2-Phenyl-bicyclo- [2,2,1] -heptan-2- (N-methylpiperidol-4)-carbonsäureester und dessen Salze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
|
|
FR2155927A1
(en)
|
1971-10-15 |
1973-05-25 |
Synthelabo |
1-phenylcyclo hexane carboxylic acid esters - with antispasmodic and anticholinergic activity
|
|
FR2168881A1
(en)
|
1972-01-25 |
1973-09-07 |
Synthelabo |
Tropanol 1-phenylcycloalkane carboxylic ester salts - spasmolytics and cholinergics
|
|
FR2208649A1
(en)
|
1972-12-01 |
1974-06-28 |
Synthelabo |
1-(2-Thienyl)cycloalkane carboxylic ester salts - with spasmolytic and anticholinergic activity
|
|
GB8334494D0
(en)
*
|
1983-12-24 |
1984-02-01 |
Tanabe Seiyaku Co |
Carbostyril derivatives
|
|
GR1001529B
(el)
|
1990-09-07 |
1994-03-31 |
Elmuquimica Farm Sl |
Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
|
|
SE9003057D0
(sv)
|
1990-09-26 |
1990-09-26 |
Astra Ab |
New process
|
|
SK4699A3
(en)
|
1996-07-29 |
2000-04-10 |
Pharmacia & Upjohn Ab |
Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation
|
|
DK0937041T3
(da)
|
1996-11-11 |
2003-08-11 |
Christian R Noe |
Anvendelse af et farmaceutisk egnet salt af (3R,2'R)-3-[(cyclopentil-hydroxyphenylacetyl)oxyl]-1,1-dimethyl-pyrrolidinium til fremstilling af et lægemiddel
|
|
US6613795B2
(en)
*
|
1996-11-11 |
2003-09-02 |
Christian Noe |
Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments
|
|
ES2165768B1
(es)
|
1999-07-14 |
2003-04-01 |
Almirall Prodesfarma Sa |
Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
|
|
GB0015876D0
(en)
|
2000-06-28 |
2000-08-23 |
Novartis Ag |
Organic compounds
|
|
IL156558A0
(en)
|
2000-12-28 |
2004-01-04 |
Almirall Prodesfarma Ag |
Novel quinuclidine derivatives and medicinal compositions containing the same
|
|
JP4143413B2
(ja)
|
2001-03-22 |
2008-09-03 |
グラクソ グループ リミテッド |
β２−アドレナリン受容体アゴニストとしてのホルムアニリド誘導体
|
|
JP2004532874A
(ja)
|
2001-04-03 |
2004-10-28 |
アリックス セラピューティクス |
抗コリン作用性化合物および使用法
|
|
PT1383786E
(pt)
|
2001-04-30 |
2008-12-30 |
Glaxo Group Ltd |
Derivados anti-inflamatórios de éster 17.beta-carbotioato de androstano com um grupo éster ciclíco na posição 17.alfa
|
|
US20030229058A1
(en)
|
2001-11-13 |
2003-12-11 |
Moran Edmund J. |
Aryl aniline beta2 adrenergic receptor agonists
|
|
TWI249515B
(en)
|
2001-11-13 |
2006-02-21 |
Theravance Inc |
Aryl aniline beta2 adrenergic receptor agonists
|
|
DE10216333A1
(de)
|
2002-04-13 |
2003-10-30 |
Boehringer Ingelheim Pharma |
Neue Carbonsäureester mit anticholonerger Wirksamkeit, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
ES2206021B1
(es)
|
2002-04-16 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de pirrolidinio.
|
|
EP1556034B1
(en)
|
2002-10-11 |
2008-04-16 |
Pfizer Limited |
Indole derivatives as beta-2 agonists
|
|
US7056916B2
(en)
*
|
2002-11-15 |
2006-06-06 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Medicaments for the treatment of chronic obstructive pulmonary disease
|
|
AR044134A1
(es)
*
|
2003-05-02 |
2005-08-24 |
Novartis Ag |
Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
|
|
PE20050231A1
(es)
|
2003-06-24 |
2005-05-20 |
Novartis Ag |
Derivados de piperidinium y pirrolidinium como antagonistas del receptor muscarinico m3
|
|
EP1684767A1
(en)
|
2003-11-03 |
2006-08-02 |
Norton Healthcare Limited |
Soft steroid compositions for use in dry powder inhalers
|
|
JPWO2006025324A1
(ja)
|
2004-08-30 |
2008-05-08 |
小野薬品工業株式会社 |
トロパン化合物およびそれらを有効成分として含有する医薬組成物
|
|
EP1797040A1
(en)
|
2004-09-29 |
2007-06-20 |
Ranbaxy Laboratories Limited |
Muscarinic receptor antagonists
|
|
EP1807391A4
(en)
|
2004-10-29 |
2010-01-06 |
Astrazeneca Ab |
NOVEL SULFONAMIDE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR AND FOR THE TREATMENT OF INFLAMMATORY DISEASES
|
|
GB0424284D0
(en)
*
|
2004-11-02 |
2004-12-01 |
Novartis Ag |
Organic compounds
|
|
GB0428416D0
(en)
|
2004-12-24 |
2005-02-02 |
Novartis Ag |
Organic compounds
|
|
TW200722418A
(en)
|
2005-04-20 |
2007-06-16 |
Astrazeneca Ab |
Novel compounds
|
|
EP1912942A1
(en)
|
2005-08-01 |
2008-04-23 |
AstraZeneca AB |
Novel piperidine derivatives as chemokine receptor modulators useful for the treatment of respiratory diseases.
|
|
TW200738635A
(en)
|
2005-08-02 |
2007-10-16 |
Astrazeneca Ab |
New salt
|
|
GB0516313D0
(en)
|
2005-08-08 |
2005-09-14 |
Argenta Discovery Ltd |
Azole derivatives and their uses
|
|
BRPI0614290A2
(pt)
|
2005-08-08 |
2011-03-22 |
Argenta Discovery Ltd |
derivados de biciclo [ 2.2.1 ] hept-7-ilamina e seus usos
|
|
TW200738658A
(en)
|
2005-08-09 |
2007-10-16 |
Astrazeneca Ab |
Novel compounds
|
|
TW200738659A
(en)
|
2005-08-29 |
2007-10-16 |
Astrazeneca Ab |
Novel compounds
|
|
US20090182033A1
(en)
|
2005-12-16 |
2009-07-16 |
Argenta Discovery Ltd. |
Cyclic Amine Derivatives and Their Uses
|
|
WO2007123465A1
(en)
|
2006-04-24 |
2007-11-01 |
Astrazeneca Ab |
New alkyl esters of cyclic amino alcohols with muscarinic m3 receptor antagonist activity, useful for treating e.g. chronic bronchial obstruction, asthma and overactive bladder
|
|
BRPI0714463A2
(pt)
|
2006-07-19 |
2013-04-02 |
Astrazeneca Ab |
compostos de espiropiperidina tricÍclicos, sua sÍntese e seus usos como moduladores de atividade receptora de quimiocina
|
|
WO2008017827A2
(en)
|
2006-08-08 |
2008-02-14 |
Argenta Discovery Limited |
Azole and thiazole derivatives and their uses
|
|
GB0702384D0
(en)
|
2007-02-07 |
2007-03-21 |
Argenta Discovery Ltd |
Chemical compounds
|
|
JP2010501533A
(ja)
|
2006-08-21 |
2010-01-21 |
アージェンタ ディスカバリー リミテッド |
Ｍ３レセプター調節物質として有用な窒素含有複素環化合物
|
|
EP1894568A1
(en)
|
2006-08-31 |
2008-03-05 |
Novartis AG |
Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
|
|
WO2008059239A1
(en)
|
2006-11-14 |
2008-05-22 |
Astrazeneca Ab |
Novel compounds 514
|
|
TW200825084A
(en)
*
|
2006-11-14 |
2008-06-16 |
Astrazeneca Ab |
New compounds 521
|
|
AU2007336054A1
(en)
|
2006-12-19 |
2008-06-26 |
Astrazeneca Ab |
Quinuclidinol derivatives as muscarinic receptor antagonists
|
|
WO2008075006A1
(en)
|
2006-12-19 |
2008-06-26 |
Astrazeneca Ab |
Piperldinum compounds for treatment of obstructive pulmonary diseases ( copd)
|
|
TW200833670A
(en)
|
2006-12-20 |
2008-08-16 |
Astrazeneca Ab |
Novel compounds 569
|
|
WO2008096093A1
(en)
|
2007-02-06 |
2008-08-14 |
Argenta Discovery Ltd. |
Oxazole and thiazole derivatives and their uses
|
|
WO2008096094A1
(en)
|
2007-02-06 |
2008-08-14 |
Argenta Discovery Ltd. |
Bicyclor[2.2.1]hept-7-ylamine derivatives as muscarinic m3 receptor modulators
|
|
GB0702414D0
(en)
|
2007-02-07 |
2007-03-21 |
Argenta Discovery Ltd |
Oxazole and thiazole derivatives and their uses 2
|
|
GB0702382D0
(en)
|
2007-02-07 |
2007-03-21 |
Argenta Discovery Ltd |
New salt
|
|
GB0702413D0
(en)
|
2007-02-07 |
2007-03-21 |
Argenta Discovery Ltd |
New chemical compounds
|
|
WO2008096129A1
(en)
|
2007-02-07 |
2008-08-14 |
Argenta Discovery Ltd |
Nitrogen containing hetrocyclic compounds useful as bifunctional modulators of m3 receptors and beta- 2 receptors
|
|
GB0702416D0
(en)
|
2007-02-07 |
2007-03-21 |
Argenta Discovery Ltd |
New combination
|
|
BRPI0807004A2
(pt)
|
2007-02-07 |
2014-04-15 |
Argenta Discovery Ltd |
Sal
|
|
GB0702385D0
(en)
|
2007-02-07 |
2007-03-21 |
Argenta Discovery Ltd |
New combination
|
|
GB0702456D0
(en)
|
2007-02-08 |
2007-03-21 |
Astrazeneca Ab |
New combination
|
|
GB0702457D0
(en)
|
2007-02-08 |
2007-03-21 |
Astrazeneca Ab |
New combination 666
|
|
KR20090110353A
(ko)
|
2007-02-15 |
2009-10-21 |
아젠터 디스커버리 리미티드 |
Ｍ３ 무스카린 수용체로서의 헤테로시클릭 유도체
|
|
GB0704000D0
(en)
|
2007-03-01 |
2007-04-11 |
Astrazeneca Ab |
Salts 670
|
|
WO2008149053A1
(en)
|
2007-06-08 |
2008-12-11 |
Argenta Discovery Ltd. |
Bicycl0 [2. 2. 1] he pt- 2-ylamine derivates and their use
|
|
WO2008149110A1
(en)
|
2007-06-08 |
2008-12-11 |
Argenta Discovery Limited |
Bicyclor [2.2.1] hept-7-ylamine derivatives and their use in the treatment of diseases and conditions in which m3 muscarinic receptor activity and beta-adrenergic activity are implicated
|
|
WO2009098453A1
(en)
|
2008-02-06 |
2009-08-13 |
Astrazeneca Ab |
Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists
|
|
WO2009098455A1
(en)
|
2008-02-06 |
2009-08-13 |
Astrazeneca Ab |
2- (9h-xanthen-9-yl) -oxazol derivatives as m3 muscarinic receptor antagonists for the treatment of asthma and chronic obstructive lung disease
|
|
HRP20120968T1
(hr)
|
2008-02-06 |
2013-01-31 |
Astrazeneca Ab |
Spojevi
|
|
EA017627B1
(ru)
|
2008-05-13 |
2013-01-30 |
Астразенека Аб |
Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
|
|
GB0808707D0
(en)
|
2008-05-13 |
2008-06-18 |
Argenta Discovery Ltd |
New compounds 275
|
|
GB0808708D0
(en)
|
2008-05-13 |
2008-06-18 |
Astrazeneca Ab |
New compounds 274
|
|
CN102088976B
(zh)
|
2008-05-13 |
2012-12-26 |
阿斯利康(瑞典)有限公司 |
包含毒蕈碱性受体拮抗剂和β2-肾上腺素受体激动剂的药物产品
|
|
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(en)
|
2008-05-13 |
2008-06-18 |
Astrazeneca Ab |
New combination 295
|
|
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(en)
|
2008-06-17 |
2008-07-23 |
Astrazeneca Ab |
New combination
|
|
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(en)
|
2008-06-17 |
2008-07-23 |
Astrazeneca Ab |
New combination 376
|
|
WO2009153536A1
(en)
|
2008-06-17 |
2009-12-23 |
Argenta Discovery Limited |
1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
|
|
WO2010015792A1
(en)
|
2008-08-06 |
2010-02-11 |
Argenta Discovery Limited |
Nitrogen containing heterocyclic compounds useful as bifunctional modulators of m3 receptors and beta-2 receptors
|
|
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(en)
|
2008-08-12 |
2010-02-18 |
Astrazeneca Ab |
2-hydroxy-ethanesulfonate salt
|
|
WO2010018352A1
(en)
|
2008-08-12 |
2010-02-18 |
Argenta Discovery Limited |
Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated
|
|
GB0814728D0
(en)
|
2008-08-12 |
2008-09-17 |
Argenta Discovery Ltd |
New combination
|
|
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(en)
|
2008-08-12 |
2008-09-17 |
Argenta Discovery Ltd |
New combination
|