JP2011519891A5 - - Google Patents
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- Publication number
- JP2011519891A5 JP2011519891A5 JP2011507892A JP2011507892A JP2011519891A5 JP 2011519891 A5 JP2011519891 A5 JP 2011519891A5 JP 2011507892 A JP2011507892 A JP 2011507892A JP 2011507892 A JP2011507892 A JP 2011507892A JP 2011519891 A5 JP2011519891 A5 JP 2011519891A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclobutyl
- carbonyl
- azetidin
- oxy
- diazepane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *OC(**#N)=O Chemical compound *OC(**#N)=O 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08155915.5 | 2008-05-08 | ||
| EP08155915 | 2008-05-08 | ||
| US13946108P | 2008-12-19 | 2008-12-19 | |
| US61/139,461 | 2008-12-19 | ||
| PCT/EP2009/055418 WO2009135842A1 (en) | 2008-05-08 | 2009-05-05 | Azetidines and cyclobutanes as histamine h3 receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011519891A JP2011519891A (ja) | 2011-07-14 |
| JP2011519891A5 true JP2011519891A5 (cg-RX-API-DMAC10.html) | 2012-05-10 |
| JP5780954B2 JP5780954B2 (ja) | 2015-09-16 |
Family
ID=39720542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011507892A Expired - Fee Related JP5780954B2 (ja) | 2008-05-08 | 2009-05-05 | ヒスタミンｈ３受容体アンタゴニストとしてのアゼチジン類及びシクロブタン類 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8691804B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2300422B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP5780954B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN102015636B (cg-RX-API-DMAC10.html) |
| BR (1) | BRPI0913057A2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2721303C (cg-RX-API-DMAC10.html) |
| IL (1) | IL208613A (cg-RX-API-DMAC10.html) |
| TW (1) | TWI454468B (cg-RX-API-DMAC10.html) |
| WO (1) | WO2009135842A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0815591B8 (pt) | 2007-08-22 | 2021-05-25 | Astrazeneca Ab | composto, composição farmacêutica, e, uso de um composto. |
| EP2391617B1 (en) | 2009-02-02 | 2015-11-11 | Evotec AG | Azetidines as histamine h3 receptor antagonists |
| TW201039825A (en) | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
| CN102471235A (zh) * | 2009-07-11 | 2012-05-23 | 拜耳医药股份有限公司 | 利用环烷基的放射性标记方法 |
| AU2011218491C1 (en) | 2010-02-18 | 2015-05-14 | Astrazeneca Ab | Processes for making cyclopropyl amide derivatives and intermediates associated therewith |
| EA201291384A1 (ru) * | 2010-07-06 | 2013-07-30 | Астразенека Аб | Терапевтические агенты 976 |
| EA023260B1 (ru) | 2011-02-23 | 2016-05-31 | Сувен Лайф Сайенсиз Лимитед | Новые соединения в качестве лигандов гистаминовых h-рецепторов |
| UY34194A (es) | 2011-07-15 | 2013-02-28 | Astrazeneca Ab | ?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad? |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| CA2878217C (en) | 2012-08-23 | 2016-05-17 | Suven Life Sciences Limited | Acrylamide compounds as histamine h3 receptor ligands |
| EP2905276A4 (en) * | 2012-09-05 | 2016-03-09 | Zhejiang Hisun Pharm Co Ltd | CRYSTALLINE FORMS OF AZETIDINONE COMPOUNDS AND MANUFACTURING METHOD |
| US20230130739A1 (en) | 2020-03-26 | 2023-04-27 | Cyclerion Therapeutics, Inc. | DEUTERATED sGC STIMULATORS |
| CN112279809A (zh) * | 2020-09-23 | 2021-01-29 | 山东省海洋化工科学研究院 | 一种2-氰基-4-氟吡啶的制备方法 |
| CN115073276A (zh) * | 2022-07-15 | 2022-09-20 | 济南大学 | 一种泊沙康唑主环杂质的制备及控制方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956359A (en) | 1985-02-28 | 1990-09-11 | A. H. Robins Company, Inc. | 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics |
| ZA861210B (en) | 1985-02-28 | 1987-10-28 | Robins Co Inc A H | 3-aryloxyazetidinecarboxamides as anticonvulsants and antiepileptics |
| US6559140B2 (en) * | 2000-03-09 | 2003-05-06 | Abbott Laboratories | Cyclic and bicyclic diamino histamine-3 receptor antagonists |
| WO2003004480A2 (en) * | 2001-07-02 | 2003-01-16 | Novo Nordisk A/S | Substituted piperazine and diazepanes as histamine h3 receptor agonists |
| DE10150310A1 (de) | 2001-10-11 | 2003-04-24 | Bayer Ag | Substituierte Piperazincyclohexancarbonsäureamide und ihre Verwendung |
| US20080045506A1 (en) | 2004-10-15 | 2008-02-21 | Glaxo Group Limited | Pyrrolidine Derivatives as Histamine Receptors Ligands |
| ATE488496T1 (de) | 2005-06-22 | 2010-12-15 | Pfizer Prod Inc | Histamin-3-rezeptorantagonisten |
| US8158673B2 (en) * | 2005-10-27 | 2012-04-17 | Pfizer Inc. | Histamine-3 receptor antagonists |
| CA2634235A1 (en) * | 2005-12-21 | 2007-07-05 | Schering Corporation | Combination of an h3 antagonist/inverse agonist and an appetite suppressant |
| BRPI0707916A2 (pt) | 2006-01-13 | 2011-05-17 | Hoffmann La Roche | compostos, processo para a sua manufatura, composições farmacêuticas que os compreendem e uso destes compostos |
| US8106208B2 (en) * | 2006-05-18 | 2012-01-31 | Albireo Ab | Benzamide compounds that act as NK receptor antagonists |
| CN105712977B (zh) * | 2007-11-20 | 2021-06-29 | 詹森药业有限公司 | 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物 |
-
2009
- 2009-05-05 CA CA2721303A patent/CA2721303C/en active Active
- 2009-05-05 WO PCT/EP2009/055418 patent/WO2009135842A1/en not_active Ceased
- 2009-05-05 US US12/991,225 patent/US8691804B2/en not_active Expired - Fee Related
- 2009-05-05 BR BRPI0913057A patent/BRPI0913057A2/pt not_active Application Discontinuation
- 2009-05-05 EP EP09742060.8A patent/EP2300422B1/en active Active
- 2009-05-05 CN CN200980117615.XA patent/CN102015636B/zh not_active Expired - Fee Related
- 2009-05-05 JP JP2011507892A patent/JP5780954B2/ja not_active Expired - Fee Related
- 2009-05-07 TW TW098115068A patent/TWI454468B/zh not_active IP Right Cessation
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2010
- 2010-10-11 IL IL208613A patent/IL208613A/en active IP Right Grant