JP2011519833A - 半減期が延長された第ｉｘ因子コンジュゲート - Google Patents
半減期が延長された第ｉｘ因子コンジュゲート Download PDFInfo
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| DK2101821T3 (da) | 2006-12-15 | 2014-10-06 | Baxter Healthcare Sa | Faktor VIIA-(poly)sialinsyre-konjugat med forlænget halveringstid in vivo |
| BR112012001814A8 (pt) | 2009-07-27 | 2018-02-06 | Baxalta GmbH | Conjugados de proteína de coagulação sanguínea |
| EP3081233B1 (en) | 2009-07-27 | 2020-12-23 | Baxalta GmbH | Glycopolysialylation of proteins other than blood coagulation proteins |
| US8642737B2 (en) | 2010-07-26 | 2014-02-04 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| US8809501B2 (en) | 2009-07-27 | 2014-08-19 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| RU2744370C2 (ru) | 2009-07-27 | 2021-03-05 | Баксалта Инкорпорейтед | Конъюгаты белков свертывания крови |
| EP2467166A2 (en) * | 2009-08-20 | 2012-06-27 | CSL Behring GmbH | Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders |
| GB201007356D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIIa |
| GB201007357D0 (en) * | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIII |
| MX375112B (es) * | 2010-07-09 | 2025-03-06 | Biogen Hemophilia Inc | Polipéptidos de factor ix y métodos para usarlos. |
| ES2800983T3 (es) | 2010-12-22 | 2021-01-07 | Baxalta GmbH | Materiales y métodos para conjugar un derivado de ácido graso soluble en agua con una proteína |
| EP3412314A1 (en) * | 2011-05-27 | 2018-12-12 | Baxalta GmbH | Therapeutic proteins conjugated to polysialic acid and methods of preparing same |
| BR112014031613A2 (pt) * | 2012-06-19 | 2017-07-25 | Polytherics Ltd | processo para preparação de conjugados de anticorpos e conjugados de anticorpos |
| WO2014052490A1 (en) | 2012-09-25 | 2014-04-03 | Biogen Idec Ma Inc. | Methods of using fix polypeptides |
| SG11201505926VA (en) | 2013-03-15 | 2015-09-29 | Biogen Ma Inc | Factor ix polypeptide formulations |
| AR099340A1 (es) * | 2014-02-12 | 2016-07-13 | Novo Nordisk As | Conjugados del factor de coagulación ix |
| EA202092926A3 (ru) | 2014-03-24 | 2021-10-29 | Биовератив Терапьютикс Инк. | Лиофилизированные составы, содержащие фактор ix |
| GB2564389A (en) | 2017-07-04 | 2019-01-16 | Green Running Ltd | A system and method for utility management |
Citations (5)
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| WO2005033140A1 (ja) * | 2003-09-30 | 2005-04-14 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | 高純度血液凝固ｉｘ因子調製物およびその精製方法 |
| JP2007527382A (ja) * | 2003-07-11 | 2007-09-27 | ポリセリックス リミテッド | 複合生物学的分子及びそれらの調製 |
| WO2007126808A1 (en) * | 2006-03-31 | 2007-11-08 | Baxter International Inc | Pegylated factor viii |
| WO2007135182A2 (en) * | 2006-05-24 | 2007-11-29 | Novo Nordisk Health Care Ag | Factor ix analogues having prolonged in vivo half life |
| JP2008505119A (ja) * | 2004-06-30 | 2008-02-21 | ネクター セラピューティクス アラバマ，コーポレイション | 高分子−第ｉｘ因子部分の抱合体 |
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| US5171569A (en) | 1985-03-15 | 1992-12-15 | National Research Development Corporation | Factor IX preparations uncontaminated by plasma components or pox virus |
| US5268275A (en) | 1991-05-08 | 1993-12-07 | The University Of North Carolina At Chapel Hill | Vitamin K-dependent carboxylase |
| US5621039A (en) * | 1993-06-08 | 1997-04-15 | Hallahan; Terrence W. | Factor IX- polymeric conjugates |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| WO1999003496A1 (en) | 1997-07-21 | 1999-01-28 | The University Of North Carolina At Chapel Hill | Factor ix antihemophilic factor with increased clotting activity |
| WO2000054787A1 (en) | 1999-03-16 | 2000-09-21 | The Children's Hospital Of Philadelphia | Enhanced gamma-carboxylation of recombinant vitamin k-dependent clotting factors |
| WO2001058935A2 (en) * | 2000-02-11 | 2001-08-16 | Maxygen Aps | FACTOR VII OR VIIa-LIKE MOLECULES |
| KR101031206B1 (ko) * | 2002-12-31 | 2011-04-27 | 넥타르 테라퓨틱스 | 말레암산 중합체 유도체 및 이의 바이오컨쥬게이트 |
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- 2009-04-24 AU AU2009239641A patent/AU2009239641B2/en not_active Ceased
- 2009-04-24 BR BRPI0911350A patent/BRPI0911350A2/pt not_active IP Right Cessation
- 2009-04-24 UA UAA201013989A patent/UA101497C2/ru unknown
- 2009-04-24 RU RU2010147813/15A patent/RU2496521C2/ru not_active IP Right Cessation
- 2009-04-24 JP JP2011505616A patent/JP2011519833A/ja active Pending
- 2009-04-24 MX MX2010011672A patent/MX2010011672A/es active IP Right Grant
- 2009-04-24 ES ES09734192.9T patent/ES2466340T3/es active Active
- 2009-04-24 CN CN200980119877XA patent/CN102046205A/zh active Pending
- 2009-04-24 NZ NZ588854A patent/NZ588854A/en not_active IP Right Cessation
- 2009-04-24 US US12/989,555 patent/US20110183906A1/en not_active Abandoned
- 2009-04-24 MY MYPI2010004993A patent/MY158228A/en unknown
- 2009-04-24 WO PCT/IB2009/005763 patent/WO2009130602A2/en not_active Ceased
- 2009-04-24 DK DK09734192.9T patent/DK2280734T3/da active
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- 2010-10-24 IL IL208908A patent/IL208908A0/en unknown
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015512927A (ja) * | 2012-04-16 | 2015-04-30 | カンタブ バイオファーマシューティカルズ パテンツ リミテッド | 最適化された皮下治療薬 |
| JP2018024684A (ja) * | 2012-04-16 | 2018-02-15 | カンタブ バイオファーマシューティカルズ パテンツ リミテッド | 最適化された皮下治療薬 |
| JP2019131593A (ja) * | 2012-04-16 | 2019-08-08 | カンタブ バイオファーマシューティカルズ パテンツ リミテッド | 最適化された皮下治療薬 |
Also Published As
| Publication number | Publication date |
|---|---|
| MY158228A (en) | 2016-09-15 |
| WO2009130602A2 (en) | 2009-10-29 |
| WO2009130602A3 (en) | 2010-02-11 |
| EP2280734B1 (en) | 2014-02-26 |
| RU2010147813A (ru) | 2012-05-27 |
| UA101497C2 (ru) | 2013-04-10 |
| CO6300965A2 (es) | 2011-07-21 |
| BRPI0911350A2 (pt) | 2017-12-05 |
| AU2009239641A1 (en) | 2009-10-29 |
| RU2496521C2 (ru) | 2013-10-27 |
| US20110183906A1 (en) | 2011-07-28 |
| DK2280734T3 (da) | 2014-05-26 |
| ES2466340T3 (es) | 2014-06-10 |
| AU2009239641B2 (en) | 2013-11-07 |
| WO2009130602A9 (en) | 2010-04-22 |
| EP2280734A2 (en) | 2011-02-09 |
| CA2722169A1 (en) | 2009-10-29 |
| HK1151986A1 (en) | 2012-02-17 |
| KR20110016440A (ko) | 2011-02-17 |
| MX2010011672A (es) | 2011-03-02 |
| NZ588854A (en) | 2011-12-22 |
| NI201000177A (es) | 2011-08-29 |
| IL208908A0 (en) | 2011-01-31 |
| ECSP10010632A (es) | 2011-02-28 |
| CR11763A (es) | 2011-04-26 |
| CN102046205A (zh) | 2011-05-04 |
| ZA201007559B (en) | 2012-01-25 |
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