JP2011518790A5 - - Google Patents
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- Publication number
- JP2011518790A5 JP2011518790A5 JP2011505362A JP2011505362A JP2011518790A5 JP 2011518790 A5 JP2011518790 A5 JP 2011518790A5 JP 2011505362 A JP2011505362 A JP 2011505362A JP 2011505362 A JP2011505362 A JP 2011505362A JP 2011518790 A5 JP2011518790 A5 JP 2011518790A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- different
- cells
- members
- polyclonal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000004027 cell Anatomy 0.000 claims 37
- 238000000034 method Methods 0.000 claims 33
- 102000004169 proteins and genes Human genes 0.000 claims 33
- 108090000623 proteins and genes Proteins 0.000 claims 33
- 238000004519 manufacturing process Methods 0.000 claims 8
- 238000000746 purification Methods 0.000 claims 5
- 239000008186 active pharmaceutical agent Substances 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 229940088679 drug related substance Drugs 0.000 claims 4
- 210000003527 eukaryotic cell Anatomy 0.000 claims 3
- 238000011081 inoculation Methods 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 230000013595 glycosylation Effects 0.000 claims 2
- 238000006206 glycosylation reaction Methods 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 241000699802 Cricetulus griseus Species 0.000 claims 1
- 241000196324 Embryophyta Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000002950 fibroblast Anatomy 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 201000000050 myeloid neoplasm Diseases 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4738908P | 2008-04-23 | 2008-04-23 | |
| US61/047,389 | 2008-04-23 | ||
| DKPA200800580 | 2008-04-23 | ||
| DKPA200800580 | 2008-04-23 | ||
| PCT/DK2009/050094 WO2009129814A1 (en) | 2008-04-23 | 2009-04-23 | Methods for manufacturing a polyclonal protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518790A JP2011518790A (ja) | 2011-06-30 |
| JP2011518790A5 true JP2011518790A5 (enExample) | 2012-05-31 |
Family
ID=40091979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011505362A Withdrawn JP2011518790A (ja) | 2008-04-23 | 2009-04-23 | ポリクローナルタンパク質を製造する方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110117605A1 (enExample) |
| EP (1) | EP2280998A1 (enExample) |
| JP (1) | JP2011518790A (enExample) |
| KR (1) | KR20110016899A (enExample) |
| CN (1) | CN102007146A (enExample) |
| AU (1) | AU2009240386A1 (enExample) |
| BR (1) | BRPI0910454A2 (enExample) |
| CA (1) | CA2722348A1 (enExample) |
| IL (1) | IL208163A0 (enExample) |
| MX (1) | MX2010011293A (enExample) |
| NZ (1) | NZ588651A (enExample) |
| RU (1) | RU2010147652A (enExample) |
| SG (1) | SG189793A1 (enExample) |
| WO (1) | WO2009129814A1 (enExample) |
| ZA (1) | ZA201006765B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2011001930A (es) * | 2008-08-29 | 2011-04-21 | Symphogen As | Metodo para clonar anticuerpos derivados de aves. |
| ES2692379T3 (es) | 2010-11-01 | 2018-12-03 | Symphogen A/S | Anticuerpos anti-HER3 y composiciones |
| CA2817751C (en) | 2010-11-16 | 2019-04-30 | Excelimmune, Inc. | Methods for producing recombinant proteins |
| WO2013164689A2 (en) | 2012-05-02 | 2013-11-07 | Lantto, Johan | Humanized pan-her antibody compositions |
| US20160289633A1 (en) * | 2013-12-20 | 2016-10-06 | Biogen Ma Inc. | Use of Perfusion Seed Cultures to Improve Biopharmaceutical Fed-Batch Production Capacity and Product Quality |
| WO2016042412A1 (en) | 2014-09-16 | 2016-03-24 | Symphogen A/S | Anti-met antibodies and compositions |
| DE102014220306B3 (de) * | 2014-10-07 | 2015-09-03 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Automatisches Verfahren zur Beobachtung von Zellkulturwachstum |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| EP3455243B1 (en) | 2016-05-11 | 2021-03-24 | Cytiva BioProcess R&D AB | Separation matrix |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| ES2909833T3 (es) | 2016-05-11 | 2022-05-10 | Cytiva Bioprocess R & D Ab | Método de limpieza y/o desinfección de una matriz de separación |
| US11708390B2 (en) | 2016-05-11 | 2023-07-25 | Cytiva Bioprocess R&D Ab | Method of storing a separation matrix |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| CN110621698B (zh) | 2017-04-05 | 2024-04-12 | 法国施维雅药厂 | 靶向pd-1、tim-3及lag-3的组合疗法 |
| WO2019103976A1 (en) * | 2017-11-22 | 2019-05-31 | Culture Biosciences, Inc. | Fermentation automation workcell |
| US12071607B2 (en) * | 2018-06-01 | 2024-08-27 | Lonza Ltd. | Midscale model for organic growth and phasing |
| MA52945A (fr) | 2018-06-22 | 2021-04-28 | Genmab As | Procédé de production d'un mélange contrôlé d'au moins deux anticorps différents |
| WO2024240634A1 (en) | 2023-05-19 | 2024-11-28 | Les Laboratoires Servier | Anti-met antibodies, antibody-drug conjugates, compositions and uses thereof |
| US20250263653A1 (en) * | 2024-02-16 | 2025-08-21 | Lanzatech, Inc. | Methods and apparatus for the production of protein |
| KR102687341B1 (ko) * | 2024-04-09 | 2024-07-23 | 주식회사 휴온스랩 | 온전한 형태의 히알루로니다제의 생산방법 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1231268T3 (da) * | 1994-01-31 | 2005-11-21 | Univ Boston | Polyklonale antistofbiblioteker |
| EP1283720B1 (en) * | 2000-05-26 | 2007-04-18 | Symphogen A/S | Recombinant or purified polyclonal antibodies for treating allergy |
| US6849259B2 (en) * | 2000-06-16 | 2005-02-01 | Symphogen A/S | Polyclonal antibody composition for treating allergy |
| US6610472B1 (en) * | 2000-10-31 | 2003-08-26 | Genetastix Corporation | Assembly and screening of highly complex and fully human antibody repertoire in yeast |
| EP1337631A2 (en) * | 2000-11-28 | 2003-08-27 | Applied Molecular Evolution, Inc. | Eukaryotic expression libraries based on double lox recombination and methods of use |
| SI1523496T1 (sl) * | 2002-07-18 | 2011-11-30 | Merus B V | Rekombinantno proizvajanje zmesi protiteles |
| CA2512647C (en) * | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| EP1706079B1 (en) * | 2003-08-14 | 2013-02-20 | ThromboGenics N.V. | Antibodies against factor viii with modified glycosylation in the variable region |
| RU2426795C2 (ru) * | 2004-07-20 | 2011-08-20 | Симфоген А/С | Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии |
| BRPI0513706A (pt) * | 2004-07-20 | 2008-05-13 | Symphogen As | anticorpo policlonal recombinante anti-rhesus d e métodos de produção |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| JP2009518320A (ja) * | 2005-12-05 | 2009-05-07 | シュムフォウエン アクティーゼルスカブ | 抗オルトポックスウイルス組換えポリクローナル抗体 |
| TW200846362A (en) * | 2007-02-09 | 2008-12-01 | Symphogen As | A polyclonal antibody product |
| NZ581316A (en) * | 2007-05-25 | 2012-02-24 | Symphogen As | Method for manufacturing a recombinant polyclonal protein |
-
2009
- 2009-04-23 BR BRPI0910454A patent/BRPI0910454A2/pt not_active IP Right Cessation
- 2009-04-23 KR KR1020107026241A patent/KR20110016899A/ko not_active Withdrawn
- 2009-04-23 US US12/989,340 patent/US20110117605A1/en not_active Abandoned
- 2009-04-23 CA CA2722348A patent/CA2722348A1/en not_active Abandoned
- 2009-04-23 WO PCT/DK2009/050094 patent/WO2009129814A1/en not_active Ceased
- 2009-04-23 SG SG2013028964A patent/SG189793A1/en unknown
- 2009-04-23 CN CN2009801131977A patent/CN102007146A/zh active Pending
- 2009-04-23 EP EP09734906A patent/EP2280998A1/en not_active Withdrawn
- 2009-04-23 NZ NZ588651A patent/NZ588651A/en not_active IP Right Cessation
- 2009-04-23 JP JP2011505362A patent/JP2011518790A/ja not_active Withdrawn
- 2009-04-23 RU RU2010147652/10A patent/RU2010147652A/ru not_active Application Discontinuation
- 2009-04-23 MX MX2010011293A patent/MX2010011293A/es active IP Right Grant
- 2009-04-23 AU AU2009240386A patent/AU2009240386A1/en not_active Abandoned
-
2010
- 2010-09-15 IL IL208163A patent/IL208163A0/en unknown
- 2010-09-21 ZA ZA2010/06765A patent/ZA201006765B/en unknown
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