JP2011518228A5 - - Google Patents
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- Publication number
- JP2011518228A5 JP2011518228A5 JP2011506420A JP2011506420A JP2011518228A5 JP 2011518228 A5 JP2011518228 A5 JP 2011518228A5 JP 2011506420 A JP2011506420 A JP 2011506420A JP 2011506420 A JP2011506420 A JP 2011506420A JP 2011518228 A5 JP2011518228 A5 JP 2011518228A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- effective amount
- composition
- enhancer compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 18
- 125000000217 alkyl group Chemical group 0.000 claims 16
- 239000003623 enhancer Substances 0.000 claims 14
- 241000233866 Fungi Species 0.000 claims 6
- 229940121375 antifungal agent Drugs 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 239000003429 antifungal agent Substances 0.000 claims 4
- 206010017533 Fungal infection Diseases 0.000 claims 3
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 3
- 208000031888 Mycoses Diseases 0.000 claims 3
- 229940125904 compound 1 Drugs 0.000 claims 3
- 229960002509 miconazole Drugs 0.000 claims 3
- 125000006163 5-membered heteroaryl group Chemical group 0.000 claims 2
- 230000000843 anti-fungal effect Effects 0.000 claims 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 150000004677 hydrates Chemical class 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- 125000000547 substituted alkyl group Chemical group 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 208000007027 Oral Candidiasis Diseases 0.000 claims 1
- 206010046914 Vaginal infection Diseases 0.000 claims 1
- 201000008100 Vaginitis Diseases 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- AICOOMRHRUFYCM-ZRRPKQBOSA-N oxazine, 1 Chemical compound C([C@@H]1[C@H](C(C[C@]2(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@]21C)=O)CC1=CC2)C[C@H]1[C@@]1(C)[C@H]2N=C(C(C)C)OC1 AICOOMRHRUFYCM-ZRRPKQBOSA-N 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4695308P | 2008-04-22 | 2008-04-22 | |
| US61/046,953 | 2008-04-22 | ||
| PCT/US2009/041403 WO2009132101A1 (en) | 2008-04-22 | 2009-04-22 | Methods of treating fungal infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518228A JP2011518228A (ja) | 2011-06-23 |
| JP2011518228A5 true JP2011518228A5 (enExample) | 2013-05-16 |
Family
ID=40790885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506420A Pending JP2011518228A (ja) | 2008-04-22 | 2009-04-22 | 真菌感染症の治療法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120252820A1 (enExample) |
| EP (1) | EP2282730A1 (enExample) |
| JP (1) | JP2011518228A (enExample) |
| CN (1) | CN102083425A (enExample) |
| AU (1) | AU2009239385A1 (enExample) |
| CA (1) | CA2722404A1 (enExample) |
| MX (1) | MX2010011678A (enExample) |
| WO (1) | WO2009132101A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014130922A1 (en) * | 2013-02-25 | 2014-08-28 | Trustees Of Boston University | Compositions and methods for treating fungal infections |
| CN103800437A (zh) * | 2013-12-31 | 2014-05-21 | 芜湖乐锐思信息咨询有限公司 | 一种治疗虫霉病的中药 |
| CN105641678A (zh) * | 2014-12-03 | 2016-06-08 | 博瑞生物医药(苏州)股份有限公司 | 阿尼芬净胃肠外制剂及制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6505398A (enExample) * | 1965-04-28 | 1966-10-31 | ||
| IL53440A0 (en) * | 1977-11-22 | 1978-01-31 | Teva Pharma | 2-adamantyl hydrazines their preparation and pharmaceutical compositions containing them |
| US4923852A (en) * | 1987-06-11 | 1990-05-08 | Merck & Co., Inc. | Aminoalkyl naphthalenediols as host resistance enhancers against viral infections |
| FR2631028B1 (fr) * | 1988-05-09 | 1990-07-13 | Cird | Adamantyl-2 isothiazoline-4 ones-3, leur procede de preparation et leur utilisation comme agents bactericides et fongicides |
| CN1638770A (zh) * | 2002-09-13 | 2005-07-13 | 新药物研究瑞典股份公司 | 组合物和增效方法 |
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2009
- 2009-04-22 MX MX2010011678A patent/MX2010011678A/es not_active Application Discontinuation
- 2009-04-22 EP EP09735352A patent/EP2282730A1/en not_active Withdrawn
- 2009-04-22 CN CN200980121923XA patent/CN102083425A/zh active Pending
- 2009-04-22 US US13/513,149 patent/US20120252820A1/en not_active Abandoned
- 2009-04-22 WO PCT/US2009/041403 patent/WO2009132101A1/en not_active Ceased
- 2009-04-22 JP JP2011506420A patent/JP2011518228A/ja active Pending
- 2009-04-22 AU AU2009239385A patent/AU2009239385A1/en not_active Abandoned
- 2009-04-22 CA CA2722404A patent/CA2722404A1/en not_active Abandoned