JP2012513416A5 - - Google Patents

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Publication number
JP2012513416A5
JP2012513416A5 JP2011542631A JP2011542631A JP2012513416A5 JP 2012513416 A5 JP2012513416 A5 JP 2012513416A5 JP 2011542631 A JP2011542631 A JP 2011542631A JP 2011542631 A JP2011542631 A JP 2011542631A JP 2012513416 A5 JP2012513416 A5 JP 2012513416A5
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JP
Japan
Prior art keywords
compound
formula
optionally substituted
alkyl
membered heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011542631A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012513416A (ja
JP5719779B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001701 external-priority patent/WO2010071944A1/en
Publication of JP2012513416A publication Critical patent/JP2012513416A/ja
Publication of JP2012513416A5 publication Critical patent/JP2012513416A5/ja
Application granted granted Critical
Publication of JP5719779B2 publication Critical patent/JP5719779B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011542631A 2008-12-24 2009-12-23 キナゾリノン化合物 Expired - Fee Related JP5719779B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2008906650A AU2008906650A0 (en) 2008-12-24 Quinazolinone compounds
AU2008906650 2008-12-24
PCT/AU2009/001701 WO2010071944A1 (en) 2008-12-24 2009-12-23 Quinazolinone compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015058888A Division JP2015143249A (ja) 2008-12-24 2015-03-23 キナゾリノン化合物

Publications (3)

Publication Number Publication Date
JP2012513416A JP2012513416A (ja) 2012-06-14
JP2012513416A5 true JP2012513416A5 (enExample) 2013-02-14
JP5719779B2 JP5719779B2 (ja) 2015-05-20

Family

ID=42286805

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011542631A Expired - Fee Related JP5719779B2 (ja) 2008-12-24 2009-12-23 キナゾリノン化合物
JP2015058888A Pending JP2015143249A (ja) 2008-12-24 2015-03-23 キナゾリノン化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015058888A Pending JP2015143249A (ja) 2008-12-24 2015-03-23 キナゾリノン化合物

Country Status (6)

Country Link
US (3) US8889695B2 (enExample)
EP (1) EP2379510B1 (enExample)
JP (2) JP5719779B2 (enExample)
DK (1) DK2379510T3 (enExample)
ES (1) ES2634492T3 (enExample)
WO (1) WO2010071944A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667300B2 (en) * 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
ES2607804T3 (es) 2004-05-13 2017-04-04 Icos Corporation Quinazolinones como inhibidores de la fosfatidilinositol humana 3-quinasa delta
CN102271683B (zh) 2008-11-13 2014-07-09 吉里德卡利斯托加公司 恶性血液病的治疗
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
ES2634492T3 (es) * 2008-12-24 2017-09-28 Prana Biotechnology Ltd Compuestos de quinazolinona
EP2421536B1 (en) * 2009-04-20 2015-08-26 Gilead Calistoga LLC Methods of treatment for solid tumors
US8691829B2 (en) 2009-07-21 2014-04-08 Gilead Calistoga Llc Treatment of liver disorders with PI3K inhibitors
WO2013134288A1 (en) 2012-03-05 2013-09-12 Gilead Calistoga Llc Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
CA2886139A1 (en) 2012-12-27 2014-07-03 F. Hoffmann-La Roche Ag Comt inhibitors
CN105849108A (zh) 2013-12-20 2016-08-10 吉利德卡利斯托加公司 磷脂酰肌醇3-激酶抑制剂的制备方法
JP2017500319A (ja) 2013-12-20 2017-01-05 ギリアード カリストガ エルエルシー (s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの塩酸塩の多形形態
MX2016016530A (es) 2014-06-13 2017-03-27 Gilead Sciences Inc Inhibidores de fosfatidilinositol 3-quinasa.
CN104016929B (zh) * 2014-06-25 2016-03-30 北京理工大学 一种合成喹唑啉-4(3h)-酮的方法
US10781178B2 (en) 2015-08-12 2020-09-22 The General Hospital Corporation 8-hydroxyquinoline derivatives as diagnostic and therapeutic agents
WO2025059726A1 (en) * 2023-09-22 2025-03-27 Alterity Therapeutics Limited Novel therapy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2361403T3 (es) * 2002-03-07 2011-06-16 X-Ceptor Therapeutics, Inc. Moduladores de quinazolinona de receptores nucleares.
EP1558585B1 (en) * 2002-10-04 2013-09-25 Prana Biotechnology Limited Neurologically-active compounds
ATE440825T1 (de) * 2003-06-06 2009-09-15 Vertex Pharma Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern
MXPA06011236A (es) * 2004-04-02 2007-01-16 Prana Biotechnology Ltd Compuestos neurologicamente activos.
ES2437997T3 (es) * 2006-04-14 2014-01-15 Prana Biotechnology Limited Método de tratamiento de la degeneración macular relacionada con la edad (AMD)
JP5415942B2 (ja) * 2006-06-22 2014-02-12 プラナ バイオテクノロジー リミティッド 処置の方法およびその処置に有用な薬剤
WO2008074068A1 (en) * 2006-12-20 2008-06-26 Prana Biotechnology Limited Substituted quinoline derivatives as antiamyloidogeneic agents
ES2634492T3 (es) * 2008-12-24 2017-09-28 Prana Biotechnology Ltd Compuestos de quinazolinona

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