JP2012513416A5 - - Google Patents

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Publication number
JP2012513416A5
JP2012513416A5 JP2011542631A JP2011542631A JP2012513416A5 JP 2012513416 A5 JP2012513416 A5 JP 2012513416A5 JP 2011542631 A JP2011542631 A JP 2011542631A JP 2011542631 A JP2011542631 A JP 2011542631A JP 2012513416 A5 JP2012513416 A5 JP 2012513416A5
Authority
JP
Japan
Prior art keywords
compound
formula
optionally substituted
alkyl
membered heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011542631A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012513416A (ja
JP5719779B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001701 external-priority patent/WO2010071944A1/en
Publication of JP2012513416A publication Critical patent/JP2012513416A/ja
Publication of JP2012513416A5 publication Critical patent/JP2012513416A5/ja
Application granted granted Critical
Publication of JP5719779B2 publication Critical patent/JP5719779B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011542631A 2008-12-24 2009-12-23 キナゾリノン化合物 Expired - Fee Related JP5719779B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2008906650A AU2008906650A0 (en) 2008-12-24 Quinazolinone compounds
AU2008906650 2008-12-24
PCT/AU2009/001701 WO2010071944A1 (en) 2008-12-24 2009-12-23 Quinazolinone compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015058888A Division JP2015143249A (ja) 2008-12-24 2015-03-23 キナゾリノン化合物

Publications (3)

Publication Number Publication Date
JP2012513416A JP2012513416A (ja) 2012-06-14
JP2012513416A5 true JP2012513416A5 (enExample) 2013-02-14
JP5719779B2 JP5719779B2 (ja) 2015-05-20

Family

ID=42286805

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011542631A Expired - Fee Related JP5719779B2 (ja) 2008-12-24 2009-12-23 キナゾリノン化合物
JP2015058888A Pending JP2015143249A (ja) 2008-12-24 2015-03-23 キナゾリノン化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015058888A Pending JP2015143249A (ja) 2008-12-24 2015-03-23 キナゾリノン化合物

Country Status (6)

Country Link
US (3) US8889695B2 (enExample)
EP (1) EP2379510B1 (enExample)
JP (2) JP5719779B2 (enExample)
DK (1) DK2379510T3 (enExample)
ES (1) ES2634492T3 (enExample)
WO (1) WO2010071944A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667300B2 (en) 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
PL1761540T3 (pl) 2004-05-13 2017-06-30 Icos Corporation Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
NZ631024A (en) 2008-11-13 2016-04-29 Gilead Calistoga Llc Therapies for hematologic malignancies
DK2379510T3 (en) * 2008-12-24 2016-12-19 Prana Biotechnology Ltd quinazolinone
PT2421536E (pt) * 2009-04-20 2015-10-20 Gilead Calistoga Llc Métodos de tratamento para tumores sólidos
EP2456443A1 (en) 2009-07-21 2012-05-30 Gilead Calistoga LLC Treatment of liver disorders with pi3k inhibitors
AP2014007875A0 (en) 2012-03-05 2014-08-31 Gilead Calistoga Llc Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
MX2015006437A (es) 2012-12-27 2015-08-14 Hoffmann La Roche Inhibidores de la enzima catecol-o-metiltransferasa (comt).
PT3083630T (pt) 2013-12-20 2019-11-15 Gilead Calistoga Llc Procedimentos para inibidores da fosfatidilinositol 3-quinase
EP3083623A1 (en) 2013-12-20 2016-10-26 Gilead Calistoga LLC Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
JP6455995B2 (ja) 2014-06-13 2019-01-23 ギリアード サイエンシーズ, インコーポレイテッド ホスファチジルイノシトール3−キナーゼ阻害剤
CN104016929B (zh) * 2014-06-25 2016-03-30 北京理工大学 一种合成喹唑啉-4(3h)-酮的方法
US10781178B2 (en) 2015-08-12 2020-09-22 The General Hospital Corporation 8-hydroxyquinoline derivatives as diagnostic and therapeutic agents
WO2025059726A1 (en) * 2023-09-22 2025-03-27 Alterity Therapeutics Limited Novel therapy
WO2026011223A1 (en) * 2024-07-12 2026-01-15 Alterity Therapeutics Limited Novel salt and crystalline form
WO2026020054A1 (en) * 2024-07-18 2026-01-22 Neumora Therapeutics, Inc. Compounds and methods for treating neurological disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2361403T3 (es) * 2002-03-07 2011-06-16 X-Ceptor Therapeutics, Inc. Moduladores de quinazolinona de receptores nucleares.
CA2500952C (en) * 2002-10-04 2011-04-26 Prana Biotechnology Limited Neurologically-active compounds
EP1646615B1 (en) * 2003-06-06 2009-08-26 Vertex Pharmaceuticals Incorporated Pyrimidine derivatives as modulators of atp-binding cassette transporters
MXPA06011236A (es) 2004-04-02 2007-01-16 Prana Biotechnology Ltd Compuestos neurologicamente activos.
US20100144693A1 (en) * 2006-04-14 2010-06-10 Prana Biotechnology Limited Method of treatment of age-related macular degeneration (amd)
EP2044026B1 (en) * 2006-06-22 2014-03-26 Prana Biotechnology Limited Method of treatment of glioma brain tumour
WO2008074068A1 (en) 2006-12-20 2008-06-26 Prana Biotechnology Limited Substituted quinoline derivatives as antiamyloidogeneic agents
DK2379510T3 (en) * 2008-12-24 2016-12-19 Prana Biotechnology Ltd quinazolinone

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