JP2011515357A - 合成ホスホジエステルオリゴヌクレオチド及びその治療的使用 - Google Patents
合成ホスホジエステルオリゴヌクレオチド及びその治療的使用 Download PDFInfo
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| RU2627177C2 (ru) | 2012-06-22 | 2017-08-03 | Джентиум С.Р.Л. | Способ определения биологической активности дефибротида, основанный на применении эуглобулина |
| EP3026122A1 (en) | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Cellular-based method for determining the potency of defibrotide |
| CN111132663A (zh) | 2017-08-03 | 2020-05-08 | 爵士制药爱尔兰有限公司 | 包含高浓度核酸的制剂 |
| CN112236149A (zh) | 2018-04-12 | 2021-01-15 | 贾兹制药公司 | 用于预防和治疗细胞因子释放综合征和与免疫耗竭相关的神经毒性的去纤苷 |
| US20220023533A1 (en) | 2018-12-07 | 2022-01-27 | Jazz Phrmaceticals Ireland Limited | Subcutaneous delivery of high concentration formulations |
| US20230190783A1 (en) | 2020-02-28 | 2023-06-22 | Jazz Pharmaceuticals Ireland Limited | Delivery of low viscosity formulations |
| EP4135717A1 (en) | 2020-04-17 | 2023-02-22 | Jazz Pharmaceuticals Ireland Limited | Defibrotide treatment for the prevention of organ rejection and injury |
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| IT1170214B (it) | 1983-09-12 | 1987-06-03 | Crinos Industria Farmaco | Composizione farmaceutica per la cura delle arteriopatie periferiche |
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2009
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- 2009-03-13 KR KR1020107023194A patent/KR20100124820A/ko not_active Ceased
- 2009-03-13 AU AU2009226906A patent/AU2009226906B2/en not_active Ceased
- 2009-03-13 US US12/919,605 patent/US20110092576A1/en not_active Abandoned
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- 2009-03-13 EP EP09721382.1A patent/EP2252688B1/en active Active
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| US3770720A (en) * | 1970-11-03 | 1973-11-06 | Crinos Industria Farmaco | Process for the extraction of alkali salts of deoxyribonucleic acid from animal organs |
| US3829567A (en) * | 1970-11-03 | 1974-08-13 | Crinos Industria Farmaco | Alkali metal salts of nucleotides useful as medicines for the fibronilityc system |
| US3899481A (en) * | 1970-11-03 | 1975-08-12 | Crinos Industria Farmaco | Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs |
| JP2001002565A (ja) * | 1999-06-08 | 2001-01-09 | Crinos Ind Farmacobiolog Spa | カチオン性リポソームとポリデオキシリボヌクレオチドとの複合体 |
| US6767554B2 (en) * | 1999-06-08 | 2004-07-27 | Gentum S.P.A. | Use of complexes among cationic liposomes and polydeoxyribonucleotides and medicaments |
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2009226906B2 (en) | 2015-05-07 |
| IL207032A (en) | 2016-08-31 |
| KR20100124820A (ko) | 2010-11-29 |
| IL207032A0 (en) | 2010-12-30 |
| ES2647772T3 (es) | 2017-12-26 |
| WO2009115465A1 (en) | 2009-09-24 |
| EP2103689A1 (en) | 2009-09-23 |
| CN101978059A (zh) | 2011-02-16 |
| CA2712705C (en) | 2017-08-15 |
| CA2712705A1 (en) | 2009-09-24 |
| EP2252688A1 (en) | 2010-11-24 |
| US20110092576A1 (en) | 2011-04-21 |
| EP2252688B1 (en) | 2017-08-16 |
| DK2252688T3 (da) | 2017-11-13 |
| CN106361763A (zh) | 2017-02-01 |
| AU2009226906A1 (en) | 2009-09-24 |
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