IT1231509B - Composizione farmceutica ad uso topico per la terapia della fragilita' capillare. - Google Patents

Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.

Info

Publication number
IT1231509B
IT1231509B IT8921651A IT2165189A IT1231509B IT 1231509 B IT1231509 B IT 1231509B IT 8921651 A IT8921651 A IT 8921651A IT 2165189 A IT2165189 A IT 2165189A IT 1231509 B IT1231509 B IT 1231509B
Authority
IT
Italy
Prior art keywords
therapy
topical use
pharmceutic
composition
capillary fragility
Prior art date
Application number
IT8921651A
Other languages
English (en)
Other versions
IT8921651A0 (it
Inventor
Marisa Mantovani
Roberto Porta
Giuseppe Prino
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of IT8921651A0 publication Critical patent/IT8921651A0/it
Priority to IT8921651A priority Critical patent/IT1231509B/it
Priority to AU59173/90A priority patent/AU623028B2/en
Priority to CA002021874A priority patent/CA2021874A1/en
Priority to ES90202172T priority patent/ES2045768T3/es
Priority to KR1019900012316A priority patent/KR910005876A/ko
Priority to EP90202172A priority patent/EP0416678B1/en
Priority to DE90202172T priority patent/DE69004532T2/de
Priority to DK90202172.4T priority patent/DK0416678T3/da
Priority to AT90202172T priority patent/ATE97001T1/de
Priority to US07/568,126 priority patent/US5116617A/en
Priority to JP2230745A priority patent/JPH0399019A/ja
Priority to PT95212A priority patent/PT95212B/pt
Application granted granted Critical
Publication of IT1231509B publication Critical patent/IT1231509B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/755—Polymers containing halogen
    • A61K31/76—Polymers containing halogen of vinyl chloride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8921651A 1989-09-07 1989-09-07 Composizione farmceutica ad uso topico per la terapia della fragilita' capillare. IT1231509B (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT8921651A IT1231509B (it) 1989-09-07 1989-09-07 Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
AU59173/90A AU623028B2 (en) 1989-09-07 1990-07-20 Pharmaceutical composition for topic use for the therapeutical treatment of capillary fragility
CA002021874A CA2021874A1 (en) 1989-09-07 1990-07-24 Pharmaceutical composition for topic use for the therapeutical treatment of capillary fragility
DE90202172T DE69004532T2 (de) 1989-09-07 1990-08-10 Topisch anzuwendende Defibrotid enthaltende Arzneizubereitungen.
KR1019900012316A KR910005876A (ko) 1989-09-07 1990-08-10 모세혈관 취약증의 치료를 위한 극소용 약학적 조성물
EP90202172A EP0416678B1 (en) 1989-09-07 1990-08-10 Topical compositions containing Defibrotide
ES90202172T ES2045768T3 (es) 1989-09-07 1990-08-10 Composiciones topicas que contienen defibrotida.
DK90202172.4T DK0416678T3 (da) 1989-09-07 1990-08-10 Topiske præparater indeholdende Defibrotid
AT90202172T ATE97001T1 (de) 1989-09-07 1990-08-10 Topisch anzuwendende defibrotid enthaltende arzneizubereitungen.
US07/568,126 US5116617A (en) 1989-09-07 1990-08-16 Pharmaceutical composition for topical use in the treatment of the capillary fragility
JP2230745A JPH0399019A (ja) 1989-09-07 1990-09-03 毛細血管脆弱の処置の局所的使用のための製薬学的組成物
PT95212A PT95212B (pt) 1989-09-07 1990-09-05 Processo para a preparacao de uma composicao para uso topico para o tratamento da fragilidade capilar, contendo defibrotide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8921651A IT1231509B (it) 1989-09-07 1989-09-07 Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.

Publications (2)

Publication Number Publication Date
IT8921651A0 IT8921651A0 (it) 1989-09-07
IT1231509B true IT1231509B (it) 1991-12-07

Family

ID=11184862

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8921651A IT1231509B (it) 1989-09-07 1989-09-07 Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.

Country Status (12)

Country Link
US (1) US5116617A (it)
EP (1) EP0416678B1 (it)
JP (1) JPH0399019A (it)
KR (1) KR910005876A (it)
AT (1) ATE97001T1 (it)
AU (1) AU623028B2 (it)
CA (1) CA2021874A1 (it)
DE (1) DE69004532T2 (it)
DK (1) DK0416678T3 (it)
ES (1) ES2045768T3 (it)
IT (1) IT1231509B (it)
PT (1) PT95212B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1147777A1 (en) * 2000-04-18 2001-10-24 Crinos Industria Farmacobiologica S.p.A. Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
US8771663B2 (en) 2000-04-18 2014-07-08 Gentium Spa Formulation having mobilising activity
US7029657B2 (en) * 2002-08-02 2006-04-18 Balance Pharmaceuticals, Inc. Nasal spray steroid formulation and method
EP1872787A1 (en) * 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
EP2103689A1 (en) 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
CN103260627A (zh) 2010-11-12 2013-08-21 真蒂奥姆有限公司 去纤维蛋白多核苷酸用于预防和/或治疗移植物抗宿主病(gvhd)
DK2864496T4 (da) 2012-06-22 2021-01-04 Gentium S R L Euglobulin-baseret fremgangsmåde til bestemmelse af den biologiske aktivitet af defibrotid
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
TW201909904A (zh) 2017-08-03 2019-03-16 愛爾蘭商爵士製藥愛爾蘭有限責任公司 高濃度調配物
KR20210008478A (ko) 2018-04-12 2021-01-22 재즈 파마슈티칼즈, 인코포레이티드 면역고갈과 관련된 사이토카인 방출 증후군 및 신경독성의 예방 및 치료를 위한 데피브로타이드
WO2020118165A1 (en) 2018-12-07 2020-06-11 Jazz Pharmaceuticals Ireland Limited Subcutaneous delivery of high concentration formulations
WO2021174039A1 (en) 2020-02-28 2021-09-02 Jazz Pharmaceuticals Ireland Limited Delivery of low viscosity formulations
WO2021212055A1 (en) 2020-04-17 2021-10-21 Jazz Pharmaceuticals Ireland Limited Defibrotide treatment for the prevention of organ rejection and injury
WO2022234101A1 (en) 2021-05-06 2022-11-10 Jazz Pharmaceuticals Ireland Limited Defibrotide for the treatment and prevention of acute respiratory distress syndrome

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1170215B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta
IT1206341B (it) * 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Also Published As

Publication number Publication date
DK0416678T3 (da) 1993-12-20
DE69004532T2 (de) 1994-02-24
IT8921651A0 (it) 1989-09-07
ES2045768T3 (es) 1994-01-16
AU623028B2 (en) 1992-04-30
EP0416678B1 (en) 1993-11-10
CA2021874A1 (en) 1991-03-08
PT95212B (pt) 1997-06-30
DE69004532D1 (de) 1993-12-16
US5116617A (en) 1992-05-26
PT95212A (pt) 1991-05-22
ATE97001T1 (de) 1993-11-15
AU5917390A (en) 1991-03-14
KR910005876A (ko) 1991-04-27
EP0416678A1 (en) 1991-03-13
JPH0399019A (ja) 1991-04-24

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970901