PT95212A - Processo para a preparacao de uma composicao para uso topico para o tratamento da fragilidade capilar, contendo defibrotide - Google Patents

Processo para a preparacao de uma composicao para uso topico para o tratamento da fragilidade capilar, contendo defibrotide

Info

Publication number
PT95212A
PT95212A PT95212A PT9521290A PT95212A PT 95212 A PT95212 A PT 95212A PT 95212 A PT95212 A PT 95212A PT 9521290 A PT9521290 A PT 9521290A PT 95212 A PT95212 A PT 95212A
Authority
PT
Portugal
Prior art keywords
defibrotide
topical use
preparation
treatment
composition
Prior art date
Application number
PT95212A
Other languages
English (en)
Other versions
PT95212B (pt
Inventor
Marisa Mantovani
Roberto Porta
Giuseppe Prino
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of PT95212A publication Critical patent/PT95212A/pt
Publication of PT95212B publication Critical patent/PT95212B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/755—Polymers containing halogen
    • A61K31/76—Polymers containing halogen of vinyl chloride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT95212A 1989-09-07 1990-09-05 Processo para a preparacao de uma composicao para uso topico para o tratamento da fragilidade capilar, contendo defibrotide PT95212B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8921651A IT1231509B (it) 1989-09-07 1989-09-07 Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.

Publications (2)

Publication Number Publication Date
PT95212A true PT95212A (pt) 1991-05-22
PT95212B PT95212B (pt) 1997-06-30

Family

ID=11184862

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95212A PT95212B (pt) 1989-09-07 1990-09-05 Processo para a preparacao de uma composicao para uso topico para o tratamento da fragilidade capilar, contendo defibrotide

Country Status (12)

Country Link
US (1) US5116617A (pt)
EP (1) EP0416678B1 (pt)
JP (1) JPH0399019A (pt)
KR (1) KR910005876A (pt)
AT (1) ATE97001T1 (pt)
AU (1) AU623028B2 (pt)
CA (1) CA2021874A1 (pt)
DE (1) DE69004532T2 (pt)
DK (1) DK0416678T3 (pt)
ES (1) ES2045768T3 (pt)
IT (1) IT1231509B (pt)
PT (1) PT95212B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771663B2 (en) 2000-04-18 2014-07-08 Gentium Spa Formulation having mobilising activity
EP1147777A1 (en) * 2000-04-18 2001-10-24 Crinos Industria Farmacobiologica S.p.A. Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
US7029657B2 (en) * 2002-08-02 2006-04-18 Balance Pharmaceuticals, Inc. Nasal spray steroid formulation and method
EP1872787A1 (en) * 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
EP2103689A1 (en) 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
US8980862B2 (en) 2010-11-12 2015-03-17 Gentium S.P.A. Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD)
BR112014031934B1 (pt) 2012-06-22 2021-05-04 Gentium S.R.L. método com base em euglobulina para determinar a atividade biológica de defibrotide
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
CA3071544A1 (en) 2017-08-03 2019-02-07 Jazz Pharmaceuticals Ireland Limited Formulations comprising a nucleic acid in a high concentration
KR20210008478A (ko) 2018-04-12 2021-01-22 재즈 파마슈티칼즈, 인코포레이티드 면역고갈과 관련된 사이토카인 방출 증후군 및 신경독성의 예방 및 치료를 위한 데피브로타이드
WO2020118165A1 (en) 2018-12-07 2020-06-11 Jazz Pharmaceuticals Ireland Limited Subcutaneous delivery of high concentration formulations
EP4110287A1 (en) 2020-02-28 2023-01-04 Jazz Pharmaceuticals Ireland Limited Delivery of low viscosity formulations
WO2021212055A1 (en) 2020-04-17 2021-10-21 Jazz Pharmaceuticals Ireland Limited Defibrotide treatment for the prevention of organ rejection and injury
TW202308659A (zh) 2021-05-06 2023-03-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1170215B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta
IT1206341B (it) * 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Also Published As

Publication number Publication date
DK0416678T3 (da) 1993-12-20
IT8921651A0 (it) 1989-09-07
EP0416678A1 (en) 1991-03-13
KR910005876A (ko) 1991-04-27
AU623028B2 (en) 1992-04-30
CA2021874A1 (en) 1991-03-08
AU5917390A (en) 1991-03-14
US5116617A (en) 1992-05-26
PT95212B (pt) 1997-06-30
ES2045768T3 (es) 1994-01-16
EP0416678B1 (en) 1993-11-10
DE69004532T2 (de) 1994-02-24
IT1231509B (it) 1991-12-07
DE69004532D1 (de) 1993-12-16
JPH0399019A (ja) 1991-04-24
ATE97001T1 (de) 1993-11-15

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19901220

FG3A Patent granted, date of granting

Effective date: 19970313

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980930