IT1170215B - Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta - Google Patents

Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta

Info

Publication number
IT1170215B
IT1170215B IT22856/83A IT2285683A IT1170215B IT 1170215 B IT1170215 B IT 1170215B IT 22856/83 A IT22856/83 A IT 22856/83A IT 2285683 A IT2285683 A IT 2285683A IT 1170215 B IT1170215 B IT 1170215B
Authority
IT
Italy
Prior art keywords
acute renal
states
treatment
pharmaceutical composition
renal insufficiency
Prior art date
Application number
IT22856/83A
Other languages
English (en)
Other versions
IT8322856A0 (it
Inventor
Vittorio Bonomini
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Priority to IT22856/83A priority Critical patent/IT1170215B/it
Publication of IT8322856A0 publication Critical patent/IT8322856A0/it
Priority to AT84201286T priority patent/ATE65696T1/de
Priority to EP84201286A priority patent/EP0137542B1/en
Priority to CH4281/84A priority patent/CH661871A5/it
Priority to US06/649,069 priority patent/US4649134A/en
Priority to DE19843433329 priority patent/DE3433329A1/de
Priority to JP59191390A priority patent/JPH0647546B2/ja
Priority to BE0/213640A priority patent/BE900563A/fr
Application granted granted Critical
Publication of IT1170215B publication Critical patent/IT1170215B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT22856/83A 1983-09-12 1983-09-12 Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta IT1170215B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT22856/83A IT1170215B (it) 1983-09-12 1983-09-12 Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta
AT84201286T ATE65696T1 (de) 1983-09-12 1984-09-07 Verwendung von defibrotid bei der behandlung von zustaenden akuter nierenschwaeche.
EP84201286A EP0137542B1 (en) 1983-09-12 1984-09-07 Use of defibrotide in the treatment of states of acute renal insufficiency
CH4281/84A CH661871A5 (it) 1983-09-12 1984-09-07 Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta.
US06/649,069 US4649134A (en) 1983-09-12 1984-09-10 Pharmaceutical composition containing defibrotide for the treatment of states of acute renal insufficiency
DE19843433329 DE3433329A1 (de) 1983-09-12 1984-09-11 Pharmazeutische zusammensetzung zur behandlung der stadien akuter niereninsuffizienz
JP59191390A JPH0647546B2 (ja) 1983-09-12 1984-09-12 医薬組成物
BE0/213640A BE900563A (fr) 1983-09-12 1984-09-12 Composition pharmaceutique pour le traitement d'etats d'insuffisance renale aigue.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22856/83A IT1170215B (it) 1983-09-12 1983-09-12 Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta

Publications (2)

Publication Number Publication Date
IT8322856A0 IT8322856A0 (it) 1983-09-12
IT1170215B true IT1170215B (it) 1987-06-03

Family

ID=11201234

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22856/83A IT1170215B (it) 1983-09-12 1983-09-12 Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta

Country Status (8)

Country Link
US (1) US4649134A (it)
EP (1) EP0137542B1 (it)
JP (1) JPH0647546B2 (it)
AT (1) ATE65696T1 (it)
BE (1) BE900563A (it)
CH (1) CH661871A5 (it)
DE (1) DE3433329A1 (it)
IT (1) IT1170215B (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
US5223609A (en) * 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US6699985B2 (en) 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
CA2153778C (en) * 1993-01-13 2004-07-06 Arsinur Burcoglu Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
AU754242B2 (en) * 1997-04-28 2002-11-07 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
EP1325962A1 (en) * 2001-12-17 2003-07-09 Gentium S.p.A. A method for determining the biological activity of defibrotide
EP1872787A1 (en) * 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
EP1982722A1 (en) * 2007-04-16 2008-10-22 Gentium S.p.A. Use of oligotide for the treatment of renal diseases
US8515557B2 (en) 2007-11-19 2013-08-20 Cochlear Limited Electrode array for a cochlear implant
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
IT1406068B1 (it) 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
ES2694239T3 (es) 2010-11-12 2018-12-19 Gentium S.R.L. Defibrótido para su uso en profilaxis y/o tratamiento de la enfermedad de Injerto contra huésped (GVHD)
KR102038357B1 (ko) * 2012-06-22 2019-10-31 젠티엄 에스알엘 디파이브로타이드의 생물학적 활성 측정을 위한 유우글로불린에 기초한 방법
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
RU2766143C2 (ru) * 2017-07-26 2022-02-08 Джентиум С.Р.Л. Жидкая композиция дефибротида для лечения и профилактики веноокклюзионной болезни
TW201909904A (zh) * 2017-08-03 2019-03-16 愛爾蘭商爵士製藥愛爾蘭有限責任公司 高濃度調配物
WO2019200251A1 (en) 2018-04-12 2019-10-17 Jazz Pharmaceuticals, Inc. Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion
EP4135717A1 (en) 2020-04-17 2023-02-22 Jazz Pharmaceuticals Ireland Limited Defibrotide treatment for the prevention of organ rejection and injury
WO2022234101A1 (en) 2021-05-06 2022-11-10 Jazz Pharmaceuticals Ireland Limited Defibrotide for the treatment and prevention of acute respiratory distress syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB879622A (en) * 1959-07-13 1961-10-11 Farmaceutici Italia Steroids
DE1202439B (de) * 1959-11-24 1965-10-07 Cediap Centrale De Destributio Verfahren zur Herstellung von Praeparaten mit hohem Gehalt an freien Desoxyribonucleinsaeuren aus Fischmilch
FR2575M (fr) * 1962-03-19 1964-06-08 Cediap Centrale De Distrib D A Procédé de préparation d'un médicament a base d'adn (acide désoxyribonucléique) en milieu vital d'origine et produit nouveau en résultant.
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs

Also Published As

Publication number Publication date
DE3433329A1 (de) 1985-03-28
JPH0647546B2 (ja) 1994-06-22
JPS6084224A (ja) 1985-05-13
IT8322856A0 (it) 1983-09-12
US4649134A (en) 1987-03-10
EP0137542B1 (en) 1991-07-31
EP0137542A2 (en) 1985-04-17
CH661871A5 (it) 1987-08-31
DE3433329C2 (it) 1993-07-22
BE900563A (fr) 1985-01-02
ATE65696T1 (de) 1991-08-15
EP0137542A3 (en) 1987-09-02

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960910