JP2011512323A5 - - Google Patents
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- Publication number
- JP2011512323A5 JP2011512323A5 JP2010533155A JP2010533155A JP2011512323A5 JP 2011512323 A5 JP2011512323 A5 JP 2011512323A5 JP 2010533155 A JP2010533155 A JP 2010533155A JP 2010533155 A JP2010533155 A JP 2010533155A JP 2011512323 A5 JP2011512323 A5 JP 2011512323A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- prostaglandin
- composition according
- hydrogen
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 125000000217 alkyl group Chemical group 0.000 claims description 8
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 8
- 210000000130 stem cell Anatomy 0.000 claims 19
- 239000000203 mixture Substances 0.000 claims 15
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 12
- -1 prostaglandin compound Chemical class 0.000 claims 12
- 125000001931 aliphatic group Chemical group 0.000 claims 6
- 125000002947 alkylene group Chemical group 0.000 claims 6
- 150000001408 amides Chemical class 0.000 claims 6
- 230000001548 androgenic effect Effects 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 6
- 150000002148 esters Chemical class 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 229920006395 saturated elastomer Polymers 0.000 claims 6
- 238000006467 substitution reaction Methods 0.000 claims 6
- 210000001185 bone marrow Anatomy 0.000 claims 4
- 230000004069 differentiation Effects 0.000 claims 4
- 230000035755 proliferation Effects 0.000 claims 4
- 230000001105 regulatory effect Effects 0.000 claims 4
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 208000032467 Aplastic anaemia Diseases 0.000 claims 1
- 208000010392 Bone Fractures Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 208000001132 Osteoporosis Diseases 0.000 claims 1
- 230000010478 bone regeneration Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000001988 somatic stem cell Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 0 **C(C(B*C(*)(*)**)C(C1)N)C1I Chemical compound **C(C(B*C(*)(*)**)C(C1)N)C1I 0.000 description 7
- 125000004066 1-hydroxyethyl group Chemical group [H]OC([H])([*])C([H])([H])[H] 0.000 description 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2971308P | 2008-02-19 | 2008-02-19 | |
| PCT/JP2009/053474 WO2009104807A1 (en) | 2008-02-19 | 2009-02-19 | Composition for modulating stem cell growth with prostaglandins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011512323A JP2011512323A (ja) | 2011-04-21 |
| JP2011512323A5 true JP2011512323A5 (https=) | 2015-03-05 |
Family
ID=40602552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010533155A Ceased JP2011512323A (ja) | 2008-02-19 | 2009-02-19 | 幹細胞の成長を調節するための方法および組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8871752B2 (https=) |
| EP (2) | EP2303278A1 (https=) |
| JP (1) | JP2011512323A (https=) |
| KR (1) | KR20100119803A (https=) |
| CN (2) | CN104248638A (https=) |
| AR (1) | AR073158A1 (https=) |
| AU (1) | AU2009216067B2 (https=) |
| BR (1) | BRPI0907831A2 (https=) |
| CA (1) | CA2715486A1 (https=) |
| IL (1) | IL207652A0 (https=) |
| MX (1) | MX2010009131A (https=) |
| NZ (1) | NZ587348A (https=) |
| RU (1) | RU2010138603A (https=) |
| TW (1) | TW200942614A (https=) |
| WO (1) | WO2009104807A1 (https=) |
| ZA (1) | ZA201006125B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010108028A2 (en) * | 2009-03-19 | 2010-09-23 | Fate Therapeutics, Inc. | Compositions comprising cyclic amp enhancers and/or ep ligands, and methods of preparing and using the same |
| US8569279B2 (en) | 2009-05-27 | 2013-10-29 | Sucampo Ag | Method for modulating claudin mediated functions |
| EP2435049A1 (en) * | 2009-05-27 | 2012-04-04 | Sucampo AG | Pharmaceutical composition comprising prostaglandin derivatives for use in modulating claudin mediated functions and in the treatment of dermatological disorders |
| KR101171912B1 (ko) | 2010-11-29 | 2012-08-07 | 기아자동차주식회사 | 밸브브릿지 일체형 가변 밸브 액츄에이터 |
| EP2785350B1 (en) | 2011-12-02 | 2018-05-02 | Fate Therapeutics, Inc. | Improved methods of treating ischemia |
| JP6220791B2 (ja) | 2011-12-02 | 2017-10-25 | フェイト セラピューティクス,インコーポレイテッド | 増強された幹細胞組成物 |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| WO2014150602A1 (en) | 2013-03-15 | 2014-09-25 | Fate Therapeutics, Inc. | Cell potency assay for therapeutic potential |
| US20140371304A1 (en) * | 2013-06-13 | 2014-12-18 | Sucampo Ag | Method for suppressing tumorigenicity of stem cells |
| US9918994B2 (en) | 2016-03-04 | 2018-03-20 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for muscle regeneration using prostaglandin E2 |
| JP2019513010A (ja) * | 2016-03-04 | 2019-05-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | プロスタグランジンe2を用いる、筋再生のための組成物および方法 |
| WO2018227138A1 (en) | 2017-06-09 | 2018-12-13 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for preventing or treating muscle conditions |
| RU2686718C1 (ru) * | 2018-03-12 | 2019-04-30 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Средство, стимулирующее функции мезенхимальных клеток-предшественников in vitro |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1322749C (en) * | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5166174A (en) * | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| US5221763A (en) * | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| TW224942B (https=) * | 1990-04-04 | 1994-06-11 | Adka Ueno Kk | |
| EP0503887B1 (en) * | 1991-03-14 | 1996-08-28 | R-Tech Ueno Ltd. | Promotion of wound-healing with 15-keto-prostaglandin compounds |
| CA2150287C (en) * | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
| US5703108A (en) * | 1996-02-28 | 1997-12-30 | Pfizer Inc. | Bone deposition by certain prostaglandin agonists |
| JP3187438B2 (ja) * | 1996-06-10 | 2001-07-11 | 株式会社アールテック・ウエノ | エンドセリン拮抗剤 |
| EP1267882B1 (en) | 2000-03-24 | 2009-04-15 | Sucampo AG | Prostaglandins for the treatment of eye disease caused by light irradiation like photoretinitis |
| DK1841433T3 (da) | 2005-01-27 | 2012-01-16 | Sucampo Ag | Præparat til behandling af lidelser i centralnervesystemet |
| JP4557288B2 (ja) * | 2005-01-28 | 2010-10-06 | アイシン・エィ・ダブリュ株式会社 | 画像認識装置及び画像認識方法、並びにそれを用いた位置特定装置、車両制御装置及びナビゲーション装置 |
| DE602006018583D1 (de) * | 2005-03-04 | 2011-01-13 | Sucampo Ag | Verfahren und zusammensetzung zur behandlung von peripheren gefässkrankheiten |
| US20060281818A1 (en) | 2005-03-21 | 2006-12-14 | Sucampo Ag, North Carolina State University | Method for treating mucosal disorders |
| AU2006326853B2 (en) | 2005-12-22 | 2012-02-16 | Es Cell International Pte Ltd | Direct differentiation of cardiomyocytes from human embryonic stem cells |
| RU2425876C2 (ru) | 2006-03-24 | 2011-08-10 | Чилдрен'З Медикал Сентер Корпорейшн | Способ модулирования роста гематопоэтических стволовых клеток |
| EP2094839B1 (en) | 2006-12-08 | 2020-02-05 | University of Rochester | Expansion of hematopoietic stem cells |
| EP2114411A2 (en) * | 2007-02-27 | 2009-11-11 | Sucampo AG | Composition and method for protecting mitochondria |
| FI20075417A0 (fi) * | 2007-06-05 | 2007-06-05 | Marjo-Riitta Suuronen | Koostumuksia ja menetelmiä alkion kantasolujen kasvatukseen |
-
2009
- 2009-02-18 US US12/388,048 patent/US8871752B2/en not_active Expired - Fee Related
- 2009-02-19 EP EP09712320A patent/EP2303278A1/en not_active Withdrawn
- 2009-02-19 JP JP2010533155A patent/JP2011512323A/ja not_active Ceased
- 2009-02-19 WO PCT/JP2009/053474 patent/WO2009104807A1/en not_active Ceased
- 2009-02-19 MX MX2010009131A patent/MX2010009131A/es not_active Application Discontinuation
- 2009-02-19 CA CA2715486A patent/CA2715486A1/en not_active Abandoned
- 2009-02-19 AU AU2009216067A patent/AU2009216067B2/en not_active Ceased
- 2009-02-19 BR BRPI0907831A patent/BRPI0907831A2/pt not_active IP Right Cessation
- 2009-02-19 CN CN201410464976.4A patent/CN104248638A/zh active Pending
- 2009-02-19 AR ARP090100582A patent/AR073158A1/es unknown
- 2009-02-19 KR KR1020107021031A patent/KR20100119803A/ko not_active Ceased
- 2009-02-19 EP EP13178225.2A patent/EP2656845A1/en not_active Withdrawn
- 2009-02-19 NZ NZ587348A patent/NZ587348A/en not_active IP Right Cessation
- 2009-02-19 CN CN200980114702XA patent/CN102014921A/zh active Pending
- 2009-02-19 RU RU2010138603/15A patent/RU2010138603A/ru not_active Application Discontinuation
- 2009-02-19 TW TW098105222A patent/TW200942614A/zh unknown
-
2010
- 2010-08-17 IL IL207652A patent/IL207652A0/en unknown
- 2010-08-27 ZA ZA2010/06125A patent/ZA201006125B/en unknown
-
2014
- 2014-09-16 US US14/487,153 patent/US20150005381A1/en not_active Abandoned
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