CN104248638A - 用于调节干细胞生长的含前列腺素的组合物 - Google Patents

用于调节干细胞生长的含前列腺素的组合物 Download PDF

Info

Publication number
CN104248638A
CN104248638A CN201410464976.4A CN201410464976A CN104248638A CN 104248638 A CN104248638 A CN 104248638A CN 201410464976 A CN201410464976 A CN 201410464976A CN 104248638 A CN104248638 A CN 104248638A
Authority
CN
China
Prior art keywords
group
rudimentary
hydroxyl
halogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410464976.4A
Other languages
English (en)
Chinese (zh)
Inventor
上野隆司
久能祐子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of CN104248638A publication Critical patent/CN104248638A/zh
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/132Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
    • C07C53/134Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings monocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201410464976.4A 2008-02-19 2009-02-19 用于调节干细胞生长的含前列腺素的组合物 Pending CN104248638A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2971308P 2008-02-19 2008-02-19
US61/029713 2008-02-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200980114702XA Division CN102014921A (zh) 2008-02-19 2009-02-19 用于调节干细胞生长的含前列腺素的组合物

Publications (1)

Publication Number Publication Date
CN104248638A true CN104248638A (zh) 2014-12-31

Family

ID=40602552

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201410464976.4A Pending CN104248638A (zh) 2008-02-19 2009-02-19 用于调节干细胞生长的含前列腺素的组合物
CN200980114702XA Pending CN102014921A (zh) 2008-02-19 2009-02-19 用于调节干细胞生长的含前列腺素的组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200980114702XA Pending CN102014921A (zh) 2008-02-19 2009-02-19 用于调节干细胞生长的含前列腺素的组合物

Country Status (16)

Country Link
US (2) US8871752B2 (https=)
EP (2) EP2656845A1 (https=)
JP (1) JP2011512323A (https=)
KR (1) KR20100119803A (https=)
CN (2) CN104248638A (https=)
AR (1) AR073158A1 (https=)
AU (1) AU2009216067B2 (https=)
BR (1) BRPI0907831A2 (https=)
CA (1) CA2715486A1 (https=)
IL (1) IL207652A0 (https=)
MX (1) MX2010009131A (https=)
NZ (1) NZ587348A (https=)
RU (1) RU2010138603A (https=)
TW (1) TW200942614A (https=)
WO (1) WO2009104807A1 (https=)
ZA (1) ZA201006125B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2408444A4 (en) * 2009-03-19 2012-09-26 Fate Therapeutics Inc COMPOSITIONS WITH CYCLIC AMP AMPLIFIERS AND / OR EP LIGANDS, AND METHOD FOR THEIR PRODUCTION AND USE
US8569279B2 (en) 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
AU2010253720A1 (en) * 2009-05-27 2011-12-08 Osaka University Pharmaceutical composition comprising prostaglandin derivatives for use in modulating claudin mediated functions and in the treatment of dermatological disorders
KR101171912B1 (ko) 2010-11-29 2012-08-07 기아자동차주식회사 밸브브릿지 일체형 가변 밸브 액츄에이터
US10111907B2 (en) 2011-12-02 2018-10-30 Fate Therapeutics, Inc. Methods of treating ischemia
EP3785767A1 (en) 2011-12-02 2021-03-03 Fate Therapeutics, Inc. Enhanced stem cell composition
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US10851412B2 (en) 2013-03-15 2020-12-01 Fate Therapeutics, Inc. Cell potency assay for therapeutic potential
US20140371304A1 (en) * 2013-06-13 2014-12-18 Sucampo Ag Method for suppressing tumorigenicity of stem cells
EP3423067B1 (en) * 2016-03-04 2025-07-23 The Board of Trustees of the Leland Stanford Junior University Inhibitors of 15-hydroxyprostaglandin dehydrogenase for muscle regeneration
US9918994B2 (en) 2016-03-04 2018-03-20 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
WO2018227138A1 (en) 2017-06-09 2018-12-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing or treating muscle conditions
RU2686718C1 (ru) * 2018-03-12 2019-04-30 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) Средство, стимулирующее функции мезенхимальных клеток-предшественников in vitro

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0503887A2 (en) * 1991-03-14 1992-09-16 R-Tech Ueno Ltd. Promotion of wound-healing with 15-keto-prostaglandin compounds
WO2006080549A2 (en) * 2005-01-27 2006-08-03 Sucampo Ag Method and composition for treating central nervous system disorders
WO2006093348A2 (en) * 2005-03-04 2006-09-08 Sucampo Ag Method and composition for treating peripheral vascular diseases
WO2007112084A2 (en) * 2006-03-24 2007-10-04 Children's Medical Center Corporation Method to modulate hematopoietic stem cell growth

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5221763A (en) * 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
TW224942B (https=) * 1990-04-04 1994-06-11 Adka Ueno Kk
CA2150287C (en) * 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
US5703108A (en) * 1996-02-28 1997-12-30 Pfizer Inc. Bone deposition by certain prostaglandin agonists
WO1997047595A1 (en) * 1996-06-10 1997-12-18 R-Tech Ueno, Ltd. Endothelin antagonist
TWI284535B (en) 2000-03-24 2007-08-01 Sucampo Ag Apoptosis inhibitor
US20070204351A1 (en) 2004-01-14 2007-08-30 Davidson Bruce P Direct differentiation of cardiomyocytes from human embryonic stem cells
JP4557288B2 (ja) * 2005-01-28 2010-10-06 アイシン・エィ・ダブリュ株式会社 画像認識装置及び画像認識方法、並びにそれを用いた位置特定装置、車両制御装置及びナビゲーション装置
US20060281818A1 (en) 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
US9394520B2 (en) 2006-12-08 2016-07-19 University Of Rochester Expansion of hematopoietic stem cells
US20080207759A1 (en) * 2007-02-27 2008-08-28 Sucampo Ag Method for protecting mitochondria
FI20075417A0 (fi) * 2007-06-05 2007-06-05 Marjo-Riitta Suuronen Koostumuksia ja menetelmiä alkion kantasolujen kasvatukseen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0503887A2 (en) * 1991-03-14 1992-09-16 R-Tech Ueno Ltd. Promotion of wound-healing with 15-keto-prostaglandin compounds
WO2006080549A2 (en) * 2005-01-27 2006-08-03 Sucampo Ag Method and composition for treating central nervous system disorders
WO2006093348A2 (en) * 2005-03-04 2006-09-08 Sucampo Ag Method and composition for treating peripheral vascular diseases
WO2007112084A2 (en) * 2006-03-24 2007-10-04 Children's Medical Center Corporation Method to modulate hematopoietic stem cell growth

Also Published As

Publication number Publication date
JP2011512323A (ja) 2011-04-21
ZA201006125B (en) 2011-05-25
US20090209643A1 (en) 2009-08-20
IL207652A0 (en) 2010-12-30
MX2010009131A (es) 2010-12-06
KR20100119803A (ko) 2010-11-10
EP2303278A1 (en) 2011-04-06
CN102014921A (zh) 2011-04-13
AU2009216067B2 (en) 2014-02-13
NZ587348A (en) 2012-04-27
CA2715486A1 (en) 2009-08-27
TW200942614A (en) 2009-10-16
AU2009216067A1 (en) 2009-08-27
EP2656845A1 (en) 2013-10-30
RU2010138603A (ru) 2012-03-27
US8871752B2 (en) 2014-10-28
WO2009104807A1 (en) 2009-08-27
US20150005381A1 (en) 2015-01-01
BRPI0907831A2 (pt) 2017-04-11
AR073158A1 (es) 2010-10-20

Similar Documents

Publication Publication Date Title
CN104248638A (zh) 用于调节干细胞生长的含前列腺素的组合物
EP2162141B1 (en) Composition for treating ischemic limb disease comprising stem cells derived from adipose tissue
TWI232750B (en) Bile secretion promoting composition
TWI284535B (en) Apoptosis inhibitor
US20150099802A1 (en) Selective tumor treatment
RU2548762C2 (ru) Способ и композиция для лечения дегенерации желтого пятна
US20020022644A1 (en) Treatment of ocular hypertension and glaucoma
US20080207759A1 (en) Method for protecting mitochondria
KR20080012407A (ko) 고안압증 및 녹내장 치료용 조성물
US20140371304A1 (en) Method for suppressing tumorigenicity of stem cells
US20100305203A1 (en) Method for modulating claudin mediated functions
US20160120840A1 (en) Method and composition for treating nonerosive reflux disease
US20150057351A1 (en) Method for treating neuropathic pain
US8569279B2 (en) Method for modulating claudin mediated functions
JP2014515004A (ja) イオン輸送体の調節方法
KR20020081438A (ko) 고안압증 및 녹내장 치료용 조성물

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20141231