JP2011512160A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011512160A5 JP2011512160A5 JP2010547632A JP2010547632A JP2011512160A5 JP 2011512160 A5 JP2011512160 A5 JP 2011512160A5 JP 2010547632 A JP2010547632 A JP 2010547632A JP 2010547632 A JP2010547632 A JP 2010547632A JP 2011512160 A5 JP2011512160 A5 JP 2011512160A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amplification
- polyomavirus
- oligonucleotide probe
- step comprises
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003321 amplification Effects 0.000 claims description 60
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 60
- 238000000034 method Methods 0.000 claims description 50
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims description 32
- 239000002751 oligonucleotide probe Substances 0.000 claims description 32
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 19
- 239000000523 sample Substances 0.000 claims description 14
- 241001505332 Polyomavirus sp. Species 0.000 claims description 10
- 108020004707 nucleic acids Proteins 0.000 claims description 10
- 102000039446 nucleic acids Human genes 0.000 claims description 10
- 150000007523 nucleic acids Chemical class 0.000 claims description 10
- 230000000295 complement effect Effects 0.000 claims description 8
- 210000000056 organ Anatomy 0.000 claims description 7
- 230000003612 virological effect Effects 0.000 claims description 5
- 239000003443 antiviral agent Substances 0.000 claims description 4
- VWFCHDSQECPREK-LURJTMIESA-N Cidofovir Chemical compound NC=1C=CN(C[C@@H](CO)OCP(O)(O)=O)C(=O)N=1 VWFCHDSQECPREK-LURJTMIESA-N 0.000 claims description 2
- 108020004414 DNA Proteins 0.000 claims description 2
- 102000053602 DNA Human genes 0.000 claims description 2
- 108060003951 Immunoglobulin Proteins 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 229940088710 antibiotic agent Drugs 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 229960000724 cidofovir Drugs 0.000 claims description 2
- 210000002216 heart Anatomy 0.000 claims description 2
- 102000018358 immunoglobulin Human genes 0.000 claims description 2
- 238000001990 intravenous administration Methods 0.000 claims description 2
- 210000003734 kidney Anatomy 0.000 claims description 2
- VHOGYURTWQBHIL-UHFFFAOYSA-N leflunomide Chemical compound O1N=CC(C(=O)NC=2C=CC(=CC=2)C(F)(F)F)=C1C VHOGYURTWQBHIL-UHFFFAOYSA-N 0.000 claims description 2
- 229960000681 leflunomide Drugs 0.000 claims description 2
- 210000004185 liver Anatomy 0.000 claims description 2
- 238000011880 melting curve analysis Methods 0.000 claims description 2
- 238000012544 monitoring process Methods 0.000 claims description 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 claims description 2
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 claims description 2
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6416608P | 2008-02-20 | 2008-02-20 | |
| PCT/US2009/001032 WO2009105212A2 (en) | 2008-02-20 | 2009-02-19 | Detection of polyomavirus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011512160A JP2011512160A (ja) | 2011-04-21 |
| JP2011512160A5 true JP2011512160A5 (enExample) | 2013-03-21 |
Family
ID=40986099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010547632A Pending JP2011512160A (ja) | 2008-02-20 | 2009-02-19 | ポリオーマウイルスの検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110091866A1 (enExample) |
| JP (1) | JP2011512160A (enExample) |
| KR (1) | KR20110011600A (enExample) |
| CN (1) | CN102066580A (enExample) |
| WO (1) | WO2009105212A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012143427A1 (en) * | 2011-04-19 | 2012-10-26 | Santaris Pharma A/S | Anti polyomavirus compounds |
| CN102690894B (zh) * | 2011-06-08 | 2013-05-01 | 中国人民解放军第三〇九医院 | 一种bk病毒的检测方法、其试剂盒及应用 |
| AU2012284122B2 (en) | 2011-07-18 | 2017-06-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for inhibiting polyomavirus-associated pathology |
| CN102690895B (zh) * | 2011-07-27 | 2013-05-01 | 中国人民解放军第三〇九医院 | 一种jc病毒的检测试剂盒及应用 |
| EP2888366A4 (en) * | 2012-08-22 | 2016-03-30 | Univ California | NEW POLYMAVIRUS ASSOCIATED WITH DIARRHOE IN CHILDREN |
| CN104745723A (zh) * | 2015-01-30 | 2015-07-01 | 湖北永邦医疗科技有限公司 | 一种用于检测bk病毒的引物、探针和试剂盒 |
| CN106065420A (zh) * | 2016-07-29 | 2016-11-02 | 北京思尔成生物技术有限公司 | Bk病毒的检测方法、试剂盒及其应用 |
| US10793923B2 (en) * | 2016-11-09 | 2020-10-06 | Roche Molecular Systems, Inc. | Compositions and methods for detection of BK virus |
| FR3082524B1 (fr) * | 2018-06-18 | 2022-03-25 | Univ Paris Sud | Methode de stratification du risque de nephropathie a bk-virus apres transplantation renale |
| CA3116895A1 (en) * | 2018-10-22 | 2020-04-30 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human polyomavirus bk virus |
| KR20210047716A (ko) | 2019-10-22 | 2021-04-30 | 단국대학교 천안캠퍼스 산학협력단 | Jc 바이러스를 검출하기 위한 등온증폭 반응용 프라이머 세트 및 이의 용도 |
| CN112522440A (zh) * | 2020-11-13 | 2021-03-19 | 苏州奥根诊断科技有限公司 | 同时检测bk病毒和jc病毒的引物组和探针组及用途 |
| CN113999937B (zh) * | 2021-11-04 | 2024-07-26 | 领致生物科技(昆山)有限公司 | 一种检测bk病毒和jc病毒的试剂及应用 |
| CN115216563A (zh) * | 2022-06-20 | 2022-10-21 | 广东永诺医疗科技有限公司 | 一种用于检测jc病毒的引物、探针及试剂盒 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US6605602B1 (en) * | 2001-09-28 | 2003-08-12 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Method of treating BK virus nephropathy |
| US20060205040A1 (en) * | 2005-03-03 | 2006-09-14 | Rangarajan Sampath | Compositions for use in identification of adventitious viruses |
| US7892795B2 (en) * | 2005-08-02 | 2011-02-22 | Focus Diagnostics, Inc. | Methods and compositions for detecting BK virus |
-
2009
- 2009-02-19 US US12/918,055 patent/US20110091866A1/en not_active Abandoned
- 2009-02-19 JP JP2010547632A patent/JP2011512160A/ja active Pending
- 2009-02-19 WO PCT/US2009/001032 patent/WO2009105212A2/en not_active Ceased
- 2009-02-19 CN CN2009801129619A patent/CN102066580A/zh active Pending
- 2009-02-19 KR KR1020107020518A patent/KR20110011600A/ko not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011512160A5 (enExample) | ||
| Zhou et al. | Coupling CRISPR/Cas12a and recombinase polymerase amplification on a stand-alone microfluidics platform for fast and parallel nucleic acid detection | |
| JP2019196400A5 (enExample) | ||
| Schwaiger et al. | Detection of enteroviral ribonucleic acid in myocardial biopsies from patients with idiopathic dilated cardiomyopathy by polymerase chain reaction | |
| JP2017536813A5 (enExample) | ||
| JP2016073273A5 (enExample) | ||
| CN101253273A (zh) | 检测尿液中病毒特异性核酸的组合物和方法 | |
| JP2015511122A5 (enExample) | ||
| JP2018518147A5 (enExample) | ||
| Zhong et al. | A novel method for detection of HBVcccDNA in hepatocytes using rolling circle amplification combined with in situ PCR | |
| JP2012513216A5 (enExample) | ||
| Nazari-Vanani et al. | Electrochemical biosensing of 16s rRNA gene sequence of Enterococcus faecalis | |
| CN103695532B (zh) | 广州管圆线虫病早期检测的分子标记物及引物 | |
| JP2009518001A5 (enExample) | ||
| CN106435018A (zh) | 一种定量检测血液中hbv dna和rna的双通道实时荧光定量pcr检测方法 | |
| CN103305594A (zh) | 一种检测结核易感性的检测标靶、引物及试剂 | |
| WO2011074181A1 (ja) | 複数の遺伝子型を有するＨＩＶ、ＨＣＶ、ＨＢＶ、ＰｖＢ１９及びＷＮＶの５種類のウイルスの網羅的な検出方法、ウイルス検出用プライマーセット、マイクロアレイ及びウイルス検出用キット | |
| JP2011041526A5 (enExample) | ||
| Boldt et al. | Mutational analysis of the PITX2 and NKX2-5 genes in patients with idiopathic atrial fibrillation | |
| CN103014135B (zh) | 一种鉴定结核分枝杆菌的方法 | |
| CN102787161A (zh) | 一种检测结核分枝杆菌方法及其专用引物 | |
| CN104411834A (zh) | 子宫内膜异位的判定方法 | |
| CN104862317A (zh) | 一种肝癌细胞特异性的适配子及其制备方法 | |
| JP2017512204A5 (enExample) | ||
| JP2009511026A5 (enExample) |