JP2017512204A5 - - Google Patents
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- Publication number
- JP2017512204A5 JP2017512204A5 JP2016554883A JP2016554883A JP2017512204A5 JP 2017512204 A5 JP2017512204 A5 JP 2017512204A5 JP 2016554883 A JP2016554883 A JP 2016554883A JP 2016554883 A JP2016554883 A JP 2016554883A JP 2017512204 A5 JP2017512204 A5 JP 2017512204A5
- Authority
- JP
- Japan
- Prior art keywords
- variant
- pair
- primers
- specifically hybridize
- individual
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000014814 CACNA1C Human genes 0.000 claims 15
- 101000867811 Homo sapiens Voltage-dependent L-type calcium channel subunit alpha-1C Proteins 0.000 claims 15
- 238000000034 method Methods 0.000 claims 14
- 102100040750 CUB and sushi domain-containing protein 1 Human genes 0.000 claims 13
- 102100028284 Collagen alpha-1(XXVI) chain Human genes 0.000 claims 13
- 101000892017 Homo sapiens CUB and sushi domain-containing protein 1 Proteins 0.000 claims 13
- 101000860862 Homo sapiens Collagen alpha-1(XXVI) chain Proteins 0.000 claims 13
- 101000785573 Homo sapiens Zinc finger and SCAN domain-containing protein 4 Proteins 0.000 claims 12
- 102100026569 Zinc finger and SCAN domain-containing protein 4 Human genes 0.000 claims 12
- 239000003814 drug Substances 0.000 claims 10
- 101000802315 Homo sapiens Zinc finger protein 551 Proteins 0.000 claims 8
- 102100034649 Zinc finger protein 551 Human genes 0.000 claims 8
- 102100035433 FOXL2 neighbor protein Human genes 0.000 claims 7
- 101000877721 Homo sapiens FOXL2 neighbor protein Proteins 0.000 claims 7
- 208000024714 major depressive disease Diseases 0.000 claims 7
- 230000002068 genetic effect Effects 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 239000000523 sample Substances 0.000 claims 4
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 claims 4
- 229960002263 vortioxetine Drugs 0.000 claims 4
- 208000028698 Cognitive impairment Diseases 0.000 claims 2
- 102100021242 Dymeclin Human genes 0.000 claims 2
- 101000817629 Homo sapiens Dymeclin Proteins 0.000 claims 2
- 208000010877 cognitive disease Diseases 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- -1 LINC00348 Proteins 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 238000003759 clinical diagnosis Methods 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461948529P | 2014-03-05 | 2014-03-05 | |
| US61/948,529 | 2014-03-05 | ||
| US201462061417P | 2014-10-08 | 2014-10-08 | |
| US62/061,417 | 2014-10-08 | ||
| PCT/US2015/018701 WO2015134585A1 (en) | 2014-03-05 | 2015-03-04 | Method for treating depression and major depressive disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017512204A JP2017512204A (ja) | 2017-05-18 |
| JP2017512204A5 true JP2017512204A5 (enExample) | 2018-04-12 |
Family
ID=54055831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016554883A Pending JP2017512204A (ja) | 2014-03-05 | 2015-03-04 | うつ病および大うつ病性障害を治療するための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170137880A1 (enExample) |
| EP (1) | EP3114239A4 (enExample) |
| JP (1) | JP2017512204A (enExample) |
| KR (1) | KR20160127126A (enExample) |
| CN (1) | CN106536751A (enExample) |
| AU (1) | AU2015227296A1 (enExample) |
| CA (1) | CA2940683A1 (enExample) |
| IL (1) | IL247379A0 (enExample) |
| MA (1) | MA39485A (enExample) |
| MX (1) | MX2016011384A (enExample) |
| RU (1) | RU2016138574A (enExample) |
| WO (1) | WO2015134585A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017087735A1 (en) * | 2015-11-18 | 2017-05-26 | Millennium Pharmaceuticals, Inc. | Method for treating crohn's disease |
| US20180280381A1 (en) * | 2017-03-30 | 2018-10-04 | Rundle Research, LLC | Methods of treating depression |
| US20190216803A1 (en) | 2017-03-30 | 2019-07-18 | Rundle Research, LLC | Methods of treating depression with vortioxetine |
| EP3909600A1 (en) * | 2020-05-12 | 2021-11-17 | International Centre For Genetic Engineering And Biotechnology - ICGEB | Emid2 protein as anti-cancer treatment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101627901B1 (ko) * | 2006-06-16 | 2016-06-13 | 하. 룬트벡 아크티에 셀스카브 | 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진 |
| EP2581457A3 (en) * | 2008-01-17 | 2013-07-17 | Suregene LLC | Genetic markers of mental illness |
| WO2012031008A2 (en) * | 2010-08-31 | 2012-03-08 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| WO2012041332A2 (en) * | 2010-10-01 | 2012-04-05 | Rigshospitalet | Genetic variations in the interleukin-6 receptor gene as predictors of the response of patients to treatment with interleukin-6 receptor inhibitors |
| US9243464B2 (en) * | 2011-02-10 | 2016-01-26 | Baker Hughes Incorporated | Flow control device and methods for using same |
| WO2012109565A1 (en) * | 2011-02-10 | 2012-08-16 | Neurotherics, Llc | Genetic identification of response to antidepressant medications |
| KR102035877B1 (ko) * | 2011-11-14 | 2019-10-23 | 알파시그마 에스.피.에이. | 우울증이 있는 대상체를 위한 치료 양생법 선택을 위한 검정법 및 치료 방법 |
-
2015
- 2015-03-04 US US15/123,072 patent/US20170137880A1/en not_active Abandoned
- 2015-03-04 KR KR1020167027125A patent/KR20160127126A/ko not_active Withdrawn
- 2015-03-04 MA MA039485A patent/MA39485A/fr unknown
- 2015-03-04 EP EP15758563.9A patent/EP3114239A4/en not_active Withdrawn
- 2015-03-04 WO PCT/US2015/018701 patent/WO2015134585A1/en not_active Ceased
- 2015-03-04 AU AU2015227296A patent/AU2015227296A1/en not_active Abandoned
- 2015-03-04 MX MX2016011384A patent/MX2016011384A/es unknown
- 2015-03-04 CA CA2940683A patent/CA2940683A1/en not_active Abandoned
- 2015-03-04 RU RU2016138574A patent/RU2016138574A/ru not_active Application Discontinuation
- 2015-03-04 CN CN201580023401.1A patent/CN106536751A/zh active Pending
- 2015-03-04 JP JP2016554883A patent/JP2017512204A/ja active Pending
-
2016
- 2016-08-21 IL IL247379A patent/IL247379A0/en unknown
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