JP2011507862A - 異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用 - Google Patents

異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用 Download PDF

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JP2011507862A
JP2011507862A JP2010539519A JP2010539519A JP2011507862A JP 2011507862 A JP2011507862 A JP 2011507862A JP 2010539519 A JP2010539519 A JP 2010539519A JP 2010539519 A JP2010539519 A JP 2010539519A JP 2011507862 A JP2011507862 A JP 2011507862A
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connexin
polynucleotide
scar
scars
abnormal
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JP2011507862A5 (cg-RX-API-DMAC10.html
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デイビッド エル． ベッカー，
コリン アール． グリーン，
ブラッドフォード ジェイ． ダフト，
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コーダ セラピューティクス， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
JP2010539519A 2007-12-21 2008-12-22 異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用 Pending JP2011507862A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US887707P 2007-12-21 2007-12-21
PCT/US2008/014028 WO2009085277A2 (en) 2007-12-21 2008-12-22 Treatment of abnormal or excessive scars

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014248308A Division JP2015057431A (ja) 2007-12-21 2014-12-08 異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用

Publications (2)

Publication Number Publication Date
JP2011507862A true JP2011507862A (ja) 2011-03-10
JP2011507862A5 JP2011507862A5 (cg-RX-API-DMAC10.html) 2013-04-25

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JP2010539519A Pending JP2011507862A (ja) 2007-12-21 2008-12-22 異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用
JP2014248308A Pending JP2015057431A (ja) 2007-12-21 2014-12-08 異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用

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JP2014248308A Pending JP2015057431A (ja) 2007-12-21 2014-12-08 異常瘢痕または過剰瘢痕の治療のための抗コネキシン４３ポリヌクレオチドの使用

Country Status (7)

Country Link
US (1) US20110130710A1 (cg-RX-API-DMAC10.html)
EP (1) EP2252690A2 (cg-RX-API-DMAC10.html)
JP (2) JP2011507862A (cg-RX-API-DMAC10.html)
AU (1) AU2008343758A1 (cg-RX-API-DMAC10.html)
CA (1) CA2710388A1 (cg-RX-API-DMAC10.html)
WO (1) WO2009085277A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA201005223B (cg-RX-API-DMAC10.html)

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CN101573131B (zh) 2005-02-03 2017-12-01 科达治疗有限公司 抗‑连接蛋白化合物及其治疗应用
CN102920996A (zh) * 2007-12-11 2013-02-13 科达治疗公司 受损伤口愈合的药物组合物
CA2710380A1 (en) 2007-12-21 2009-07-09 Coda Therapeutics, Inc. Use of anti-connexin 43 poly nucleotide for the treatment of fibrotic conditions
MX351881B (es) 2012-03-01 2017-11-01 Firststring Res Inc Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act).
US20180126033A9 (en) 2012-03-14 2018-05-10 MAM Holdings of West Florida, L.L.C. Collagen compositions and uses for biomaterial implants
US10576037B2 (en) * 2012-03-14 2020-03-03 MAM Holdings of West Florida, L.L.C. Compositions comprising placental collagen for use in wound healing
JP2015513905A (ja) 2012-03-27 2015-05-18 コーダ セラピューティクス， インコーポレイテッド カドヘリン調節に基づく組成物および処置
US20140072613A1 (en) * 2012-09-10 2014-03-13 Cynthia Lander Compositions and Methods for Treating Cutaneous Scarring
WO2016029191A2 (en) 2014-08-22 2016-02-25 Auckland Uniservices Limited Channel modulators
WO2016140921A1 (en) 2015-03-02 2016-09-09 180 Therapeutics Lp Method of treating a localized fibrotic disorder using an il-33 antagonist
CN111201247A (zh) 2017-04-28 2020-05-26 奥克兰联合服务有限公司 治疗方法和新颖构建体
WO2019005643A1 (en) * 2017-06-26 2019-01-03 Next Science IP Holdings Pty Ltd METHOD OF TREATING PATHOLOGIES OF COLLAGEN FIBERS
WO2019152110A1 (en) * 2018-01-31 2019-08-08 Kci Usa, Inc. Antimicrobial composition, dressing, dressing components, and method
US12138293B2 (en) 2020-10-22 2024-11-12 Xequel Bio, Inc. Peptide formulations and ophthalmic uses thereof
US12667586B2 (en) 2023-03-07 2026-06-30 Glaukos Corporation Treatments for ocular surface disorders

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JP2001522878A (ja) * 1997-11-17 2001-11-20 ニコラス ブイー ペリコン， リポ酸を使用する瘢痕組織の治療
JP2002535377A (ja) * 1999-01-27 2002-10-22 ユニバーシテイ・カレツジ・ロンドン コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2006527234A (ja) * 2003-06-09 2006-11-30 アセンド セラピュティクス インコーポレイテッド ４−ヒドロキシタモキシフェンによる過剰瘢痕化の治療及び予防
JP2007084446A (ja) * 2005-09-20 2007-04-05 Pola Chem Ind Inc 皮膚外用剤
JP2007513148A (ja) * 2003-12-03 2007-05-24 コーダ セラピューティクス （エヌゼット） リミテッド コネキシンに対して標的化されたアンチセンス化合物およびその使用方法

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JP2002535377A (ja) * 1999-01-27 2002-10-22 ユニバーシテイ・カレツジ・ロンドン コネキシンに対するアンチセンスヌクレオチドを含む配合物
JP2006527234A (ja) * 2003-06-09 2006-11-30 アセンド セラピュティクス インコーポレイテッド ４−ヒドロキシタモキシフェンによる過剰瘢痕化の治療及び予防
JP2007513148A (ja) * 2003-12-03 2007-05-24 コーダ セラピューティクス （エヌゼット） リミテッド コネキシンに対して標的化されたアンチセンス化合物およびその使用方法
JP2007084446A (ja) * 2005-09-20 2007-04-05 Pola Chem Ind Inc 皮膚外用剤

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Publication number Publication date
CA2710388A1 (en) 2009-07-09
JP2015057431A (ja) 2015-03-26
WO2009085277A3 (en) 2009-11-26
US20110130710A1 (en) 2011-06-02
ZA201005223B (en) 2011-09-28
EP2252690A2 (en) 2010-11-24
WO2009085277A2 (en) 2009-07-09
AU2008343758A1 (en) 2009-07-09

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