JP2011506286A5 - - Google Patents
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- Publication number
- JP2011506286A5 JP2011506286A5 JP2010536446A JP2010536446A JP2011506286A5 JP 2011506286 A5 JP2011506286 A5 JP 2011506286A5 JP 2010536446 A JP2010536446 A JP 2010536446A JP 2010536446 A JP2010536446 A JP 2010536446A JP 2011506286 A5 JP2011506286 A5 JP 2011506286A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- hydroxy
- groups
- compound
- propyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 21
- -1 2-hydroxypropylene, 2,3-dihydroxybutylene Chemical group 0.000 claims 17
- 125000000217 alkyl group Chemical group 0.000 claims 16
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 9
- 229910052757 nitrogen Inorganic materials 0.000 claims 7
- 125000001424 substituent group Chemical group 0.000 claims 7
- 125000004432 carbon atom Chemical group C* 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 125000002947 alkylene group Chemical group 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 2
- 239000007983 Tris buffer Substances 0.000 claims 2
- 239000000032 diagnostic agent Substances 0.000 claims 2
- 229940039227 diagnostic agent Drugs 0.000 claims 2
- 238000002405 diagnostic procedure Methods 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000003384 imaging method Methods 0.000 claims 2
- 230000003287 optical effect Effects 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20076268 | 2007-12-05 | ||
| PCT/EP2008/066745 WO2009071605A1 (en) | 2007-12-05 | 2008-12-04 | Contrast agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011506286A JP2011506286A (ja) | 2011-03-03 |
| JP2011506286A5 true JP2011506286A5 (https=) | 2012-01-26 |
Family
ID=40409848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010536446A Pending JP2011506286A (ja) | 2007-12-05 | 2008-12-04 | 造影剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100303734A1 (https=) |
| EP (1) | EP2231200A1 (https=) |
| JP (1) | JP2011506286A (https=) |
| CN (1) | CN101888858A (https=) |
| WO (1) | WO2009071605A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101520187B1 (ko) * | 2013-10-25 | 2015-05-13 | 주식회사 대웅제약 | 이오프로마이드의 중간체의 제조방법 |
| EP3220887A1 (en) | 2014-11-21 | 2017-09-27 | Technical University of Denmark | Gel formulations for local drug release |
| SG11201809729XA (en) | 2016-05-20 | 2018-12-28 | Univ Denmark Tech Dtu | Palpable marker composition |
| EP3982922A1 (en) | 2019-06-12 | 2022-04-20 | Technical University of Denmark | Dissacharide formulations for controlled drug release |
| CN117623960B (zh) * | 2023-12-27 | 2025-10-17 | 重庆圣华曦药业股份有限公司 | 一种碘美普尔中间体的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4584401A (en) * | 1983-10-20 | 1986-04-22 | Biophysica Foundation | Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media |
| IT1245853B (it) * | 1990-11-16 | 1994-10-25 | Bracco Spa | 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
| IT1256248B (it) * | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
| EP0809519B1 (en) * | 1995-12-19 | 2002-09-11 | Bracco Research S.A. | Compositions comprising tricodobenzene polymers for imaging the gastrointestinal tract |
| ITMI20011706A1 (it) * | 2001-08-03 | 2003-02-03 | Bracco Imaging Spa | Agenti di contrasto radiografici ionici e non ionici, utilizzabili per l'indagine diagnostica combinata tramite raggi-x e risonanza magnetic |
-
2008
- 2008-12-04 JP JP2010536446A patent/JP2011506286A/ja active Pending
- 2008-12-04 CN CN2008801194401A patent/CN101888858A/zh active Pending
- 2008-12-04 WO PCT/EP2008/066745 patent/WO2009071605A1/en not_active Ceased
- 2008-12-04 US US12/744,752 patent/US20100303734A1/en not_active Abandoned
- 2008-12-04 EP EP08857217A patent/EP2231200A1/en not_active Withdrawn
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