JP2011500531A5 - - Google Patents
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- Publication number
- JP2011500531A5 JP2011500531A5 JP2010528406A JP2010528406A JP2011500531A5 JP 2011500531 A5 JP2011500531 A5 JP 2011500531A5 JP 2010528406 A JP2010528406 A JP 2010528406A JP 2010528406 A JP2010528406 A JP 2010528406A JP 2011500531 A5 JP2011500531 A5 JP 2011500531A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- dihydroxypropyl
- triiodobenzoylamino
- hydroxypropane
- aminocarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 16
- -1 2,3-dihydroxypropyl moiety Chemical group 0.000 claims 15
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 238000003384 imaging method Methods 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N isopropyl alcohol Natural products CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- XOVXFQMYXQQBHC-UHFFFAOYSA-N n-(2,3-dihydroxypropyl)-3-[[3-[[3-(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodobenzoyl]-(2,3,4-trihydroxybutylamino)amino]-2-hydroxypropyl]-(2,3,4-trihydroxybutylamino)carbamoyl]-2,4,6-triiodobenzamide Chemical compound OCC(O)CNC(=O)C1=C(I)C=C(I)C(C(=O)N(CC(O)CN(NCC(O)C(O)CO)C(=O)C=2C(=C(C(=O)NCC(O)CO)C(I)=CC=2I)I)NCC(O)C(O)CO)=C1I XOVXFQMYXQQBHC-UHFFFAOYSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20075259 | 2007-10-12 | ||
| PCT/EP2008/063585 WO2009047316A1 (en) | 2007-10-12 | 2008-10-10 | Contrast agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500531A JP2011500531A (ja) | 2011-01-06 |
| JP2011500531A5 true JP2011500531A5 (https=) | 2011-11-24 |
Family
ID=40083706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528406A Pending JP2011500531A (ja) | 2007-10-12 | 2008-10-10 | 造影剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100209356A1 (https=) |
| EP (1) | EP2200971B1 (https=) |
| JP (1) | JP2011500531A (https=) |
| CN (1) | CN101821231A (https=) |
| ES (1) | ES2413160T3 (https=) |
| WO (1) | WO2009047316A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101209633B1 (ko) * | 2009-09-09 | 2012-12-06 | 주식회사 휴메딕스 | 페길레이션된 삼요오드화 아릴 화합물 및 그를 포함하는 ｘ-선 조영제 |
| US20220242817A1 (en) * | 2021-01-12 | 2022-08-04 | Boston Scientific Scimed Inc. | Iodinated compounds having radiocontrast properties |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE344166B (https=) | 1966-12-13 | 1972-04-04 | Pharmacia Ab | |
| US3804892A (en) | 1967-12-28 | 1974-04-16 | Pharmacia Ab | Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof |
| US3763227A (en) | 1967-12-28 | 1973-10-02 | Pharmacia Ab | Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof |
| SE315974B (https=) | 1967-12-28 | 1969-10-13 | Pharmacia Ab | |
| DE2628517C2 (de) | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
| IT1207226B (it) | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
| DE3038853A1 (de) | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
| DK160868C (da) | 1982-11-08 | 1991-10-14 | Nyegaard & Co As | Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem |
| FR2634571B1 (fr) | 1988-07-19 | 1990-10-19 | Kodak Pathe | Procede d'organisation et de lecture d'un support magnetique et support en faisant application |
| GB9020091D0 (en) | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| IT1245853B (it) | 1990-11-16 | 1994-10-25 | Bracco Spa | 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
| IT1256248B (it) * | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
| GB9303992D0 (en) | 1993-02-26 | 1993-04-14 | Nycomed Imaging As | Contrast agents |
| AU6114396A (en) | 1995-06-16 | 1997-01-15 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
| EP0809519B1 (en) * | 1995-12-19 | 2002-09-11 | Bracco Research S.A. | Compositions comprising tricodobenzene polymers for imaging the gastrointestinal tract |
| US6072069A (en) | 1998-11-04 | 2000-06-06 | Biophysica, Inc. | Biodegradable nonionic contrast media |
| EP1186305A1 (en) | 2000-09-07 | 2002-03-13 | Schering Aktiengesellschaft | New brominated compounds as contrast media for X-ray mammography |
| ITMI20011706A1 (it) * | 2001-08-03 | 2003-02-03 | Bracco Imaging Spa | Agenti di contrasto radiografici ionici e non ionici, utilizzabili per l'indagine diagnostica combinata tramite raggi-x e risonanza magnetic |
| EP1492776B1 (en) | 2002-03-27 | 2008-10-29 | FUJIFILM Corporation | Iodinated triglyceride analogs |
| WO2007094683A1 (en) * | 2006-02-15 | 2007-08-23 | Ge Healthcare As | Contrast agents |
-
2008
- 2008-10-10 ES ES08805207T patent/ES2413160T3/es active Active
- 2008-10-10 JP JP2010528406A patent/JP2011500531A/ja active Pending
- 2008-10-10 EP EP08805207.1A patent/EP2200971B1/en not_active Not-in-force
- 2008-10-10 US US12/682,066 patent/US20100209356A1/en not_active Abandoned
- 2008-10-10 WO PCT/EP2008/063585 patent/WO2009047316A1/en not_active Ceased
- 2008-10-10 CN CN200880111022A patent/CN101821231A/zh active Pending
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