JP2011505838A5 - - Google Patents
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- Publication number
- JP2011505838A5 JP2011505838A5 JP2010538169A JP2010538169A JP2011505838A5 JP 2011505838 A5 JP2011505838 A5 JP 2011505838A5 JP 2010538169 A JP2010538169 A JP 2010538169A JP 2010538169 A JP2010538169 A JP 2010538169A JP 2011505838 A5 JP2011505838 A5 JP 2011505838A5
- Authority
- JP
- Japan
- Prior art keywords
- culture
- acyl
- thioesterase
- medium
- exogenous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108700021044 acyl-ACP thioesterase Proteins 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 244000005700 microbiome Species 0.000 claims 6
- 150000004665 fatty acids Chemical group 0.000 claims 5
- 239000001963 growth medium Substances 0.000 claims 5
- 230000000243 photosynthetic effect Effects 0.000 claims 5
- 108090000790 Enzymes Proteins 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 4
- 239000003463 adsorbent Substances 0.000 claims 4
- 235000014113 dietary fatty acids Nutrition 0.000 claims 4
- 229930195729 fatty acid Natural products 0.000 claims 4
- 239000000194 fatty acid Substances 0.000 claims 4
- 102000011802 Beta-ketoacyl synthases Human genes 0.000 claims 3
- 108050002233 Beta-ketoacyl synthases Proteins 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 3
- 102000005488 Thioesterase Human genes 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 239000002609 medium Substances 0.000 claims 3
- 108020002982 thioesterase Proteins 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical group C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims 1
- 108090000344 1,4-alpha-Glucan Branching Enzyme Proteins 0.000 claims 1
- 102000003925 1,4-alpha-Glucan Branching Enzyme Human genes 0.000 claims 1
- 241000219992 Cuphea Species 0.000 claims 1
- 108090000364 Ligases Proteins 0.000 claims 1
- 102000003960 Ligases Human genes 0.000 claims 1
- 108030000162 Long-chain-fatty-acid-[acyl-carrier-protein] ligases Proteins 0.000 claims 1
- 230000002349 favourable effect Effects 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 235000021588 free fatty acids Nutrition 0.000 claims 1
- 239000003456 ion exchange resin Substances 0.000 claims 1
- 229920003303 ion-exchange polymer Polymers 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 230000020477 pH reduction Effects 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 238000003259 recombinant expression Methods 0.000 claims 1
- 238000011946 reduction process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US733307P | 2007-12-11 | 2007-12-11 | |
| US61/007,333 | 2007-12-11 | ||
| PCT/US2008/086485 WO2009076559A1 (en) | 2007-12-11 | 2008-12-11 | Secretion of fatty aicds by photosynthetic microorganisms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011505838A JP2011505838A (ja) | 2011-03-03 |
| JP2011505838A5 true JP2011505838A5 (enExample) | 2012-12-20 |
| JP5465183B2 JP5465183B2 (ja) | 2014-04-09 |
Family
ID=40755894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538169A Expired - Fee Related JP5465183B2 (ja) | 2007-12-11 | 2008-12-11 | 光合成微生物による脂肪酸の分泌 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090298143A1 (enExample) |
| EP (1) | EP2231864B1 (enExample) |
| JP (1) | JP5465183B2 (enExample) |
| CN (1) | CN101952452B (enExample) |
| AU (1) | AU2008335089B2 (enExample) |
| BR (1) | BRPI0821508B1 (enExample) |
| MX (1) | MX2010006539A (enExample) |
| MY (1) | MY154028A (enExample) |
| WO (1) | WO2009076559A1 (enExample) |
| ZA (1) | ZA201004253B (enExample) |
Families Citing this family (64)
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| EP2062574B1 (en) * | 2006-09-08 | 2015-03-25 | Kaneka Corporation | Composition comprising reduced coenzyme q10 and lysolecithin |
| US8272669B2 (en) * | 2006-10-24 | 2012-09-25 | Timothy J. Flynn | Label assembly for applying a label to an object |
| JP2010528627A (ja) | 2007-06-01 | 2010-08-26 | ソラザイム、インク | 微生物による油の生産 |
| BRPI0821508B1 (pt) | 2007-12-11 | 2018-12-26 | Synthetic Genomics Inc | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| US8048654B2 (en) | 2010-06-09 | 2011-11-01 | Joule Unlimited Technologies, Inc. | Methods and compositions for the recombinant biosynthesis of fatty acids and esters |
| GB0807619D0 (en) * | 2008-04-28 | 2008-06-04 | Whitton Peter A | Production of bio fuels from plant tissue culture sources |
| AU2013201607B2 (en) * | 2008-04-28 | 2015-03-12 | Naturally Scientific Technologies Limited | Production of biofuel from tissue culture sources |
| US20120094338A1 (en) * | 2008-07-22 | 2012-04-19 | Li zhong kui | Continuous production and excretion of waxy products from photosynthetic organisms |
| US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
| AU2009308236B2 (en) | 2008-10-23 | 2016-06-30 | Lumen Bioscience, Inc. | Modified photosynthetic microorganisms for producing triglycerides |
| ES2583639T3 (es) | 2008-11-28 | 2016-09-21 | Terravia Holdings, Inc. | Producción de aceites específicos en microorganismos heterótrofos |
| US8835137B2 (en) | 2008-12-23 | 2014-09-16 | Matrix Genetics, Llc | Modified photosynthetic microorganisms with reduced glycogen and their use in producing carbon-based products |
| WO2011008565A1 (en) | 2009-06-29 | 2011-01-20 | Synthetic Genomics, Inc. | Acyl-acp thioesterase genes and uses therefor |
| US9359623B2 (en) * | 2009-07-24 | 2016-06-07 | The Regents Of The University Of California | Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms |
| US8980613B2 (en) | 2010-04-06 | 2015-03-17 | Matrix Genetics, Llc | Modified photosynthetic microorganisms for producing lipids |
| JP2011246605A (ja) * | 2010-05-26 | 2011-12-08 | Hitachi Plant Technologies Ltd | バイオ燃料製造方法 |
| SG10201504197SA (en) | 2010-05-28 | 2015-06-29 | Solazyme Inc | Food Compositions Comprising Tailored Oils |
| EP3521408B1 (en) | 2010-11-03 | 2021-12-22 | Corbion Biotech, Inc. | Genetically-engineered chlorella or prototheca microbe and oil produced therefrom |
| WO2012071439A1 (en) * | 2010-11-22 | 2012-05-31 | The Regents Of The University Of California | Host cells and methods for producing diacid compounds |
| WO2012087673A1 (en) | 2010-12-23 | 2012-06-28 | Exxonmobil Research And Engineering Company | Prokaryotic acyl-acp thioesterases for producing fatty acids in genetically engineered microorganisms |
| WO2012087675A1 (en) | 2010-12-23 | 2012-06-28 | Exxonmobil Research And Engineering Company | Culturing a microorganism in a medium with an elevated level of a carboxylate counterion source |
| CN110066836A (zh) * | 2011-02-02 | 2019-07-30 | 柯碧恩生物技术公司 | 产自重组产油微生物的定制油 |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| EP2691510A4 (en) * | 2011-03-31 | 2014-11-12 | Exxonmobil Res & Eng Co | METABOLISM DIRECTIONS BY TRANSCRIPTION FACTOR OVEREXPRESSION |
| WO2012154626A1 (en) | 2011-05-06 | 2012-11-15 | Solazyme, Inc. | Genetically engineered microorganisms that metabolize xylose |
| CA2840525A1 (en) * | 2011-06-28 | 2013-01-03 | Brookhaven Science Associates, Llc | Modified plants with increased oil content |
| CN103635571B (zh) | 2011-06-30 | 2016-12-14 | 艾克森美孚研究与工程公司 | 调控毒素和抗毒素基因用于生物防范 |
| US8951762B2 (en) | 2011-07-27 | 2015-02-10 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| US9399768B2 (en) | 2011-07-27 | 2016-07-26 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| DE102011110945A1 (de) | 2011-08-15 | 2013-02-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt |
| DE102011110946A1 (de) | 2011-08-15 | 2016-01-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen |
| CN103975070A (zh) | 2011-09-27 | 2014-08-06 | 艾克森美孚研究与工程公司 | 酰基-酰基载体蛋白(acyl-acp)蜡酯合酶 |
| PT2814972T (pt) | 2012-02-24 | 2020-06-16 | Exxonmobil Res & Eng Co | Produção melhorada de ácidos gordos e derivados de ácidos gordos por micro-organismos recombinantes |
| US9096834B2 (en) | 2012-02-24 | 2015-08-04 | Exxonmobil Research And Engineering Company | Recombinant microorganisms comprising thioesterase and lysophosphatidic acid acyltransferase genes for fatty acid production |
| US8962299B2 (en) | 2012-02-29 | 2015-02-24 | Exxonmobil Research And Engineering Company | Four-gene pathway for wax ester synthesis |
| BR112014025719A8 (pt) | 2012-04-18 | 2017-10-03 | Solazyme Inc | Óleos customizados |
| US9719114B2 (en) | 2012-04-18 | 2017-08-01 | Terravia Holdings, Inc. | Tailored oils |
| US9181568B2 (en) | 2012-04-23 | 2015-11-10 | Exxonmobil Research And Engineering Company | Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases |
| WO2014088560A1 (en) * | 2012-12-04 | 2014-06-12 | Exxonmobil Research And Engineering Company | Tetraselmis promoters and terminators for use in eukaryotic cells |
| US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
| US9249252B2 (en) | 2013-04-26 | 2016-02-02 | Solazyme, Inc. | Low polyunsaturated fatty acid oils and uses thereof |
| DE102013208228A1 (de) | 2013-05-06 | 2014-11-06 | Siemens Aktiengesellschaft | Verfahren zum Kultivieren eines Mikroorganismus in einer in vitro Kultur und Verfahren zum Herstellen eines Sekundärmetabolits |
| FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
| MX369685B (es) | 2013-10-04 | 2019-11-19 | Terravia Holdings Inc | Aceites adaptables. |
| JP6341676B2 (ja) | 2014-01-31 | 2018-06-13 | 花王株式会社 | 改変シアノバクテリア |
| WO2015149026A1 (en) | 2014-03-28 | 2015-10-01 | Solazyme, Inc. | Lauric ester compositions |
| EP3620517A3 (en) | 2014-07-10 | 2020-07-29 | Corbion Biotech, Inc. | Ketoacyl acp synthase genes and uses thereof |
| KR101735632B1 (ko) * | 2014-12-10 | 2017-05-16 | 한국과학기술연구원 | 시아노박테리아 발현 벡터 |
| JP6663856B2 (ja) * | 2014-12-22 | 2020-03-13 | 花王株式会社 | 改変シアノバクテリア |
| JP6568718B2 (ja) | 2015-05-22 | 2019-08-28 | 花王株式会社 | 脂質の製造方法 |
| JP6587468B2 (ja) * | 2015-09-11 | 2019-10-09 | 花王株式会社 | 脂質の製造方法 |
| WO2017120473A1 (en) | 2016-01-07 | 2017-07-13 | Conagen Inc. | Methods of making capsinoids by biosynthetic processes |
| US10418697B2 (en) * | 2016-02-25 | 2019-09-17 | Toshiba Client Solutions Co. Ltd. | Antenna apparatus and electronic device |
| JP6734112B2 (ja) * | 2016-05-10 | 2020-08-05 | 花王株式会社 | 脂質の製造方法 |
| US11459591B2 (en) | 2016-07-19 | 2022-10-04 | Conagen Inc. | Method for the microbial production of specific natural capsaicinoids |
| JP6971607B2 (ja) * | 2016-12-19 | 2021-11-24 | 花王株式会社 | 脂質の製造方法 |
| WO2018119343A1 (en) * | 2016-12-22 | 2018-06-28 | Conagen Inc. | Method for the microbial production of 8-methyl nonanoic acid |
| JP6934303B2 (ja) | 2017-02-08 | 2021-09-15 | 花王株式会社 | 脂肪族アルコールの生産方法 |
| EP3794017A4 (en) | 2018-05-17 | 2022-03-09 | Lumen Bioscience, Inc. | ARTHROSPIRA PLATENSIS ORAL VACCINE DELIVERY PLATFORM |
| US12252513B2 (en) | 2018-07-16 | 2025-03-18 | Lumen Bioscience, Inc. | Thermostable phycobiliproteins produced from recombinant arthrospira |
| JP7551990B2 (ja) * | 2020-08-28 | 2024-09-18 | 大成建設株式会社 | 遊離脂肪酸の分離方法と回収方法 |
| US11336975B1 (en) | 2021-02-01 | 2022-05-17 | Shure Acquisition Holdings, Inc. | Wearable device with detune-resilient antenna |
| JP7646964B2 (ja) * | 2021-08-20 | 2025-03-18 | 大成建設株式会社 | 遊離脂肪酸の回収方法、回収システム |
| GB2617381A (en) | 2022-04-07 | 2023-10-11 | Phycobloom Ltd | Engineered photosynthetic organisms |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5298421A (en) * | 1990-04-26 | 1994-03-29 | Calgene, Inc. | Plant medium-chain-preferring acyl-ACP thioesterases and related methods |
| US5179219A (en) * | 1990-11-19 | 1993-01-12 | Uop | Process for separating fatty acids and triglycerides |
| US5455167A (en) | 1991-05-21 | 1995-10-03 | Calgene Inc. | Medium-chain thioesterases in plants |
| JP2729883B2 (ja) * | 1992-10-07 | 1998-03-18 | 工業技術院長 | 藍藻を用いる有機分泌物の製造方法 |
| US6150512A (en) * | 1995-05-15 | 2000-11-21 | Yuan; Ling | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| DK0963439T3 (da) | 1997-02-19 | 2007-09-03 | Enol Energy Inc | Genmanipulerede Cyanobakterier til fremstilling af ethanol |
| US6495140B1 (en) * | 1998-01-12 | 2002-12-17 | Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada | Process for the isolation, recovery and purification of non-polar extractives |
| EP1197560A4 (en) * | 1999-07-07 | 2005-08-03 | Kyowa Hakko Kogyo Kk | PROCESS FOR PREPARING HYDROXILATED FATTY ACID AND DELTA LACTONE |
| PL207026B1 (pl) * | 2000-02-09 | 2010-10-29 | Basf Ag | Wyizolowany kwas nukleinowy, konstrukt genowy zawierający ten kwas, sekwencja aminokwasowa kodowana przez wyizolowaną sekwencję tego kwasu nukleinowego, wektor zawierający kwas nukleinowy lub konstrukt genowy, roślina transgeniczna lub mikroorganizm transgeniczny zawierający kwas nukleinowy, konstrukt genowy lub wektor, przeciwciało specyficznie wiążące się z polipeptydem kodowanym przez kwas nukleinowy, cząsteczka antysensownego kwasu nukleinowego oraz sposób wytwarzania wielonienasyconych kwasów tłuszczowych (PUFA) |
| ES2343106T3 (es) * | 2000-09-28 | 2010-07-23 | BIORIGINAL FOOD & SCIENCE CORP. | Fad4, fad5, fad5-2 y fad6, miembros de la familia de desaturasas de acidos grasos y usos de los mismos. |
| AU2005214874B2 (en) * | 2004-02-13 | 2010-02-18 | Martek Biosciences Corporation | Schizochytrium fatty acid synthase (FAS) and products and methods related thereto |
| EP1752532A1 (en) | 2005-08-09 | 2007-02-14 | Helmholtz-Zentrum für Infektionsforschung GmbH | Extracellular polyhydroxyalkanoates produced by genetically engineered microorganisms |
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US7470532B2 (en) * | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| JP5933909B2 (ja) * | 2006-05-19 | 2016-06-15 | アールイージー ライフ サイエンシズ リミテッド ライアビリティ カンパニー | 脂肪酸およびその誘導体の生産 |
| CA3178593A1 (en) | 2007-03-28 | 2008-10-02 | Genomatica, Inc. | Enhanced production of fatty acid derivatives |
| JP2010528627A (ja) | 2007-06-01 | 2010-08-26 | ソラザイム、インク | 微生物による油の生産 |
| BRPI0821508B1 (pt) | 2007-12-11 | 2018-12-26 | Synthetic Genomics Inc | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| US20110218354A1 (en) | 2008-09-19 | 2011-09-08 | President And Fellows Of Harvard College | Photoautotrophic Adipogenesis Technology (Phat) |
-
2008
- 2008-12-11 BR BRPI0821508A patent/BRPI0821508B1/pt not_active IP Right Cessation
- 2008-12-11 EP EP08860168.7A patent/EP2231864B1/en not_active Not-in-force
- 2008-12-11 AU AU2008335089A patent/AU2008335089B2/en not_active Ceased
- 2008-12-11 WO PCT/US2008/086485 patent/WO2009076559A1/en not_active Ceased
- 2008-12-11 CN CN200880126568.0A patent/CN101952452B/zh not_active Expired - Fee Related
- 2008-12-11 JP JP2010538169A patent/JP5465183B2/ja not_active Expired - Fee Related
- 2008-12-11 US US12/333,280 patent/US20090298143A1/en not_active Abandoned
- 2008-12-11 MY MYPI2010002698A patent/MY154028A/en unknown
- 2008-12-11 MX MX2010006539A patent/MX2010006539A/es unknown
-
2010
- 2010-06-15 ZA ZA2010/04253A patent/ZA201004253B/en unknown
-
2011
- 2011-12-29 US US13/340,350 patent/US10233470B2/en not_active Expired - Fee Related
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