MX2010006539A - Secrecion de acidos grasos por parte de microorganismos fotosinteticos. - Google Patents
Secrecion de acidos grasos por parte de microorganismos fotosinteticos.Info
- Publication number
- MX2010006539A MX2010006539A MX2010006539A MX2010006539A MX2010006539A MX 2010006539 A MX2010006539 A MX 2010006539A MX 2010006539 A MX2010006539 A MX 2010006539A MX 2010006539 A MX2010006539 A MX 2010006539A MX 2010006539 A MX2010006539 A MX 2010006539A
- Authority
- MX
- Mexico
- Prior art keywords
- culture
- acyl
- fatty acids
- acp
- composition
- Prior art date
Links
- 230000000243 photosynthetic effect Effects 0.000 title claims abstract description 19
- 244000005700 microbiome Species 0.000 title claims abstract description 17
- 230000028327 secretion Effects 0.000 title description 9
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 48
- 239000000194 fatty acid Substances 0.000 claims abstract description 48
- 229930195729 fatty acid Natural products 0.000 claims abstract description 48
- 150000004665 fatty acids Chemical class 0.000 claims abstract description 47
- 238000000034 method Methods 0.000 claims abstract description 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 12
- 239000001963 growth medium Substances 0.000 claims abstract description 8
- 238000003306 harvesting Methods 0.000 claims abstract description 5
- 108090000623 proteins and genes Proteins 0.000 claims description 54
- 239000002253 acid Substances 0.000 claims description 19
- 108020002982 thioesterase Proteins 0.000 claims description 19
- 102000005488 Thioesterase Human genes 0.000 claims description 17
- 108090000790 Enzymes Proteins 0.000 claims description 15
- 102000004190 Enzymes Human genes 0.000 claims description 15
- 239000002609 medium Substances 0.000 claims description 14
- 239000002245 particle Substances 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 12
- 239000000446 fuel Substances 0.000 claims description 11
- 108700021044 acyl-ACP thioesterase Proteins 0.000 claims description 8
- 239000003463 adsorbent Substances 0.000 claims description 7
- 230000001105 regulatory effect Effects 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 150000001335 aliphatic alkanes Chemical class 0.000 claims description 3
- 150000007970 thio esters Chemical class 0.000 claims description 3
- 108090000364 Ligases Proteins 0.000 claims description 2
- 102000003960 Ligases Human genes 0.000 claims description 2
- 150000001336 alkenes Chemical class 0.000 claims description 2
- 150000001720 carbohydrates Chemical class 0.000 claims description 2
- 230000001404 mediated effect Effects 0.000 claims description 2
- 150000007523 nucleic acids Chemical class 0.000 claims description 2
- 239000000654 additive Substances 0.000 claims 1
- 235000014633 carbohydrates Nutrition 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 229940081330 tena Drugs 0.000 claims 1
- 241000196324 Embryophyta Species 0.000 description 15
- 235000021588 free fatty acids Nutrition 0.000 description 13
- 239000013612 plasmid Substances 0.000 description 13
- 239000012634 fragment Substances 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 12
- 150000007513 acids Chemical class 0.000 description 11
- 210000004027 cell Anatomy 0.000 description 10
- 150000004667 medium chain fatty acids Chemical class 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 241000192584 Synechocystis Species 0.000 description 9
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 9
- 241000192581 Synechocystis sp. Species 0.000 description 7
- 239000013604 expression vector Substances 0.000 description 7
- 230000012010 growth Effects 0.000 description 7
- 150000002632 lipids Chemical class 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 235000019198 oils Nutrition 0.000 description 7
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- BPHPUYQFMNQIOC-NXRLNHOXSA-N isopropyl beta-D-thiogalactopyranoside Chemical compound CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O BPHPUYQFMNQIOC-NXRLNHOXSA-N 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 6
- 239000011347 resin Substances 0.000 description 6
- 229920005989 resin Polymers 0.000 description 6
- 238000001179 sorption measurement Methods 0.000 description 6
- 241000195628 Chlorophyta Species 0.000 description 5
- 241000219992 Cuphea Species 0.000 description 5
- 108020004414 DNA Proteins 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 238000004587 chromatography analysis Methods 0.000 description 5
- 239000013598 vector Substances 0.000 description 5
- GYSCBCSGKXNZRH-UHFFFAOYSA-N 1-benzothiophene-2-carboxamide Chemical compound C1=CC=C2SC(C(=O)N)=CC2=C1 GYSCBCSGKXNZRH-UHFFFAOYSA-N 0.000 description 4
- 241000192700 Cyanobacteria Species 0.000 description 4
- GHVNFZFCNZKVNT-UHFFFAOYSA-N Decanoic acid Natural products CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 4
- 239000004793 Polystyrene Substances 0.000 description 4
- 241001491687 Thalassiosira pseudonana Species 0.000 description 4
- 108700019146 Transgenes Proteins 0.000 description 4
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 4
- 108010031100 chloroplast transit peptides Proteins 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 230000010354 integration Effects 0.000 description 4
- 239000003550 marker Substances 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 108091026890 Coding region Proteins 0.000 description 3
- 241000195493 Cryptophyta Species 0.000 description 3
- 241000219919 Cuphea lanceolata Species 0.000 description 3
- 108090000371 Esterases Proteins 0.000 description 3
- 241000192707 Synechococcus Species 0.000 description 3
- 108700005078 Synthetic Genes Proteins 0.000 description 3
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 210000000349 chromosome Anatomy 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 238000000769 gas chromatography-flame ionisation detection Methods 0.000 description 3
- 230000006801 homologous recombination Effects 0.000 description 3
- 238000002744 homologous recombination Methods 0.000 description 3
- -1 ional fatty acid Chemical class 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 238000002955 isolation Methods 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000010561 standard procedure Methods 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 2
- 241000206761 Bacillariophyta Species 0.000 description 2
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 description 2
- 235000006008 Brassica napus var napus Nutrition 0.000 description 2
- 240000000385 Brassica napus var. napus Species 0.000 description 2
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 description 2
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 2
- 108010078791 Carrier Proteins Proteins 0.000 description 2
- 102000014914 Carrier Proteins Human genes 0.000 description 2
- 108020004705 Codon Proteins 0.000 description 2
- 240000006262 Cuphea hookeriana Species 0.000 description 2
- 241001495477 Cuphea wrightii Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 241000282326 Felis catus Species 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- 101000635799 Homo sapiens Run domain Beclin-1-interacting and cysteine-rich domain-containing protein Proteins 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 2
- 239000005642 Oleic acid Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 102100030852 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein Human genes 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 101100095302 Streptococcus gordonii secA1 gene Proteins 0.000 description 2
- 241000192593 Synechocystis sp. PCC 6803 Species 0.000 description 2
- 229910021536 Zeolite Inorganic materials 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 2
- 150000001413 amino acids Chemical group 0.000 description 2
- 239000002551 biofuel Substances 0.000 description 2
- 210000003763 chloroplast Anatomy 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000003795 desorption Methods 0.000 description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000002816 fuel additive Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 101150070444 glgB gene Proteins 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 2
- 229930027917 kanamycin Natural products 0.000 description 2
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 description 2
- 229960000318 kanamycin Drugs 0.000 description 2
- 229930182823 kanamycin A Natural products 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 2
- 239000002773 nucleotide Substances 0.000 description 2
- 125000003729 nucleotide group Chemical group 0.000 description 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 210000002706 plastid Anatomy 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 230000037452 priming Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 101150075980 psbA gene Proteins 0.000 description 2
- 238000005215 recombination Methods 0.000 description 2
- 101150108659 secA gene Proteins 0.000 description 2
- 238000012163 sequencing technique Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- UNFWWIHTNXNPBV-WXKVUWSESA-N spectinomycin Chemical compound O([C@@H]1[C@@H](NC)[C@@H](O)[C@H]([C@@H]([C@H]1O1)O)NC)[C@]2(O)[C@H]1O[C@H](C)CC2=O UNFWWIHTNXNPBV-WXKVUWSESA-N 0.000 description 2
- 229960000268 spectinomycin Drugs 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 238000013518 transcription Methods 0.000 description 2
- 230000035897 transcription Effects 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 239000010457 zeolite Substances 0.000 description 2
- RSWGJHLUYNHPMX-UHFFFAOYSA-N 1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid Chemical compound C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 1
- JTTIOYHBNXDJOD-UHFFFAOYSA-N 2,4,6-triaminopyrimidine Chemical compound NC1=CC(N)=NC(N)=N1 JTTIOYHBNXDJOD-UHFFFAOYSA-N 0.000 description 1
- 108030002854 Acetoacetyl-CoA synthases Proteins 0.000 description 1
- 108020001558 Acyl-CoA oxidase Proteins 0.000 description 1
- 101000935487 Agrobacterium fabrum (strain C58 / ATCC 33970) 3-oxopimeloyl-[acyl-carrier-protein] synthase Proteins 0.000 description 1
- 229920000310 Alpha glucan Polymers 0.000 description 1
- 241000219194 Arabidopsis Species 0.000 description 1
- 235000016425 Arthrospira platensis Nutrition 0.000 description 1
- 240000002900 Arthrospira platensis Species 0.000 description 1
- 239000000592 Artificial Cell Substances 0.000 description 1
- 241000132092 Aster Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- 244000020518 Carthamus tinctorius Species 0.000 description 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 description 1
- 241000195597 Chlamydomonas reinhardtii Species 0.000 description 1
- 108010035563 Chloramphenicol O-acetyltransferase Proteins 0.000 description 1
- 241000196319 Chlorophyceae Species 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 102000005870 Coenzyme A Ligases Human genes 0.000 description 1
- 244000018436 Coriandrum sativum Species 0.000 description 1
- 235000002787 Coriandrum sativum Nutrition 0.000 description 1
- 101100119775 Coriandrum sativum FATA gene Proteins 0.000 description 1
- 241001254186 Cuphea calophylla Species 0.000 description 1
- 241001464430 Cyanobacterium Species 0.000 description 1
- 241000380046 Cyanospira Species 0.000 description 1
- 241001299740 Cylindrospermopsis Species 0.000 description 1
- 241000721041 Dactylococcopsis Species 0.000 description 1
- 241000199914 Dinophyceae Species 0.000 description 1
- 240000006053 Garcinia mangostana Species 0.000 description 1
- 241001464794 Gloeobacter Species 0.000 description 1
- 241001464427 Gloeocapsa Species 0.000 description 1
- 241001134702 Gloeothece Species 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 101000724418 Homo sapiens Neutral amino acid transporter B(0) Proteins 0.000 description 1
- 108010011449 Long-chain-fatty-acid-CoA ligase Proteins 0.000 description 1
- 108030000162 Long-chain-fatty-acid-[acyl-carrier-protein] ligases Proteins 0.000 description 1
- 241000192701 Microcystis Species 0.000 description 1
- 102100028267 Neutral amino acid transporter B(0) Human genes 0.000 description 1
- 241000059630 Nodularia <Cyanobacteria> Species 0.000 description 1
- 241000192656 Nostoc Species 0.000 description 1
- 241000243387 Nostochopsis Species 0.000 description 1
- 241000238413 Octopus Species 0.000 description 1
- 238000012408 PCR amplification Methods 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000192141 Prochloron Species 0.000 description 1
- 241000192144 Prochlorothrix Species 0.000 description 1
- 101710150344 Protein Rev Proteins 0.000 description 1
- 241000206572 Rhodophyta Species 0.000 description 1
- 108010003581 Ribulose-bisphosphate carboxylase Proteins 0.000 description 1
- 241001575211 Rivularia <snail> Species 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 241000243446 Stigonema Species 0.000 description 1
- 241000187310 Streptomyces noursei Species 0.000 description 1
- 241001439057 Syneches Species 0.000 description 1
- 241001453296 Synechococcus elongatus Species 0.000 description 1
- 241000192589 Synechococcus elongatus PCC 7942 Species 0.000 description 1
- 101100228996 Synechocystis sp. (strain PCC 6803 / Kazusa) glgB gene Proteins 0.000 description 1
- 241001178535 Thalassiosira pseudonana CCMP1335 Species 0.000 description 1
- 241000157473 Tolypothrix Species 0.000 description 1
- 241000219793 Trifolium Species 0.000 description 1
- 102000004243 Tubulin Human genes 0.000 description 1
- 108090000704 Tubulin Proteins 0.000 description 1
- 241000530641 Tychonema Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- HCCBNDDJPKNSLM-WOQKIVQTSA-N [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-4-[[3-(2-hexadecylsulfanylethylamino)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl] hydrogen phosphate Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSCCCCCCCCCCCCCCCC)O[C@H]1N1C2=NC=NC(N)=C2N=C1 HCCBNDDJPKNSLM-WOQKIVQTSA-N 0.000 description 1
- 101150067314 aadA gene Proteins 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 125000003368 amide group Chemical group 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000003225 biodiesel Substances 0.000 description 1
- 238000010170 biological method Methods 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 101150055766 cat gene Proteins 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- ZCDOYSPFYFSLEW-UHFFFAOYSA-N chromate(2-) Chemical compound [O-][Cr]([O-])(=O)=O ZCDOYSPFYFSLEW-UHFFFAOYSA-N 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 210000001520 comb Anatomy 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000010779 crude oil Substances 0.000 description 1
- 239000012228 culture supernatant Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003828 downregulation Effects 0.000 description 1
- 238000004520 electroporation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000015114 espresso Nutrition 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000008394 flocculating agent Substances 0.000 description 1
- 239000002803 fossil fuel Substances 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 108010052221 glucan synthase Proteins 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 238000006317 isomerization reaction Methods 0.000 description 1
- 229940070765 laurate Drugs 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 229940105132 myristate Drugs 0.000 description 1
- CJWXCNXHAIFFMH-AVZHFPDBSA-N n-[(2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5r)-2-acetamido-4,5,6-trihydroxy-1-oxohexan-3-yl]oxy-3,5-dihydroxy-6-methyloxan-4-yl]acetamide Chemical compound C[C@H]1O[C@@H](O[C@@H]([C@@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)[C@H](O)[C@@H](NC(C)=O)[C@@H]1O CJWXCNXHAIFFMH-AVZHFPDBSA-N 0.000 description 1
- 230000017066 negative regulation of growth Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000012454 non-polar solvent Substances 0.000 description 1
- 210000004940 nucleus Anatomy 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- 210000000287 oocyte Anatomy 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 239000011049 pearl Substances 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000010773 plant oil Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 230000008488 polyadenylation Effects 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 230000031390 regulation of fatty acid biosynthetic process Effects 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000013605 shuttle vector Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229940082787 spirulina Drugs 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 125000003696 stearoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- 230000000476 thermogenic effect Effects 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/649—Biodiesel, i.e. fatty acid alkyl esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02T—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO TRANSPORTATION
- Y02T50/00—Aeronautics or air transport
- Y02T50/60—Efficient propulsion technologies, e.g. for aircraft
- Y02T50/678—Aviation using fuels of non-fossil origin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US733307P | 2007-12-11 | 2007-12-11 | |
| PCT/US2008/086485 WO2009076559A1 (en) | 2007-12-11 | 2008-12-11 | Secretion of fatty aicds by photosynthetic microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010006539A true MX2010006539A (es) | 2011-02-23 |
Family
ID=40755894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010006539A MX2010006539A (es) | 2007-12-11 | 2008-12-11 | Secrecion de acidos grasos por parte de microorganismos fotosinteticos. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090298143A1 (enExample) |
| EP (1) | EP2231864B1 (enExample) |
| JP (1) | JP5465183B2 (enExample) |
| CN (1) | CN101952452B (enExample) |
| AU (1) | AU2008335089B2 (enExample) |
| BR (1) | BRPI0821508B1 (enExample) |
| MX (1) | MX2010006539A (enExample) |
| MY (1) | MY154028A (enExample) |
| WO (1) | WO2009076559A1 (enExample) |
| ZA (1) | ZA201004253B (enExample) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2062574B1 (en) * | 2006-09-08 | 2015-03-25 | Kaneka Corporation | Composition comprising reduced coenzyme q10 and lysolecithin |
| US8272669B2 (en) * | 2006-10-24 | 2012-09-25 | Timothy J. Flynn | Label assembly for applying a label to an object |
| JP2010528627A (ja) | 2007-06-01 | 2010-08-26 | ソラザイム、インク | 微生物による油の生産 |
| BRPI0821508B1 (pt) | 2007-12-11 | 2018-12-26 | Synthetic Genomics Inc | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| US8048654B2 (en) | 2010-06-09 | 2011-11-01 | Joule Unlimited Technologies, Inc. | Methods and compositions for the recombinant biosynthesis of fatty acids and esters |
| GB0807619D0 (en) * | 2008-04-28 | 2008-06-04 | Whitton Peter A | Production of bio fuels from plant tissue culture sources |
| AU2013201607B2 (en) * | 2008-04-28 | 2015-03-12 | Naturally Scientific Technologies Limited | Production of biofuel from tissue culture sources |
| US20120094338A1 (en) * | 2008-07-22 | 2012-04-19 | Li zhong kui | Continuous production and excretion of waxy products from photosynthetic organisms |
| US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
| AU2009308236B2 (en) | 2008-10-23 | 2016-06-30 | Lumen Bioscience, Inc. | Modified photosynthetic microorganisms for producing triglycerides |
| ES2583639T3 (es) | 2008-11-28 | 2016-09-21 | Terravia Holdings, Inc. | Producción de aceites específicos en microorganismos heterótrofos |
| US8835137B2 (en) | 2008-12-23 | 2014-09-16 | Matrix Genetics, Llc | Modified photosynthetic microorganisms with reduced glycogen and their use in producing carbon-based products |
| WO2011008565A1 (en) | 2009-06-29 | 2011-01-20 | Synthetic Genomics, Inc. | Acyl-acp thioesterase genes and uses therefor |
| US9359623B2 (en) * | 2009-07-24 | 2016-06-07 | The Regents Of The University Of California | Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms |
| US8980613B2 (en) | 2010-04-06 | 2015-03-17 | Matrix Genetics, Llc | Modified photosynthetic microorganisms for producing lipids |
| JP2011246605A (ja) * | 2010-05-26 | 2011-12-08 | Hitachi Plant Technologies Ltd | バイオ燃料製造方法 |
| SG10201504197SA (en) | 2010-05-28 | 2015-06-29 | Solazyme Inc | Food Compositions Comprising Tailored Oils |
| EP3521408B1 (en) | 2010-11-03 | 2021-12-22 | Corbion Biotech, Inc. | Genetically-engineered chlorella or prototheca microbe and oil produced therefrom |
| WO2012071439A1 (en) * | 2010-11-22 | 2012-05-31 | The Regents Of The University Of California | Host cells and methods for producing diacid compounds |
| WO2012087673A1 (en) | 2010-12-23 | 2012-06-28 | Exxonmobil Research And Engineering Company | Prokaryotic acyl-acp thioesterases for producing fatty acids in genetically engineered microorganisms |
| WO2012087675A1 (en) | 2010-12-23 | 2012-06-28 | Exxonmobil Research And Engineering Company | Culturing a microorganism in a medium with an elevated level of a carboxylate counterion source |
| CN110066836A (zh) * | 2011-02-02 | 2019-07-30 | 柯碧恩生物技术公司 | 产自重组产油微生物的定制油 |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| EP2691510A4 (en) * | 2011-03-31 | 2014-11-12 | Exxonmobil Res & Eng Co | METABOLISM DIRECTIONS BY TRANSCRIPTION FACTOR OVEREXPRESSION |
| WO2012154626A1 (en) | 2011-05-06 | 2012-11-15 | Solazyme, Inc. | Genetically engineered microorganisms that metabolize xylose |
| CA2840525A1 (en) * | 2011-06-28 | 2013-01-03 | Brookhaven Science Associates, Llc | Modified plants with increased oil content |
| CN103635571B (zh) | 2011-06-30 | 2016-12-14 | 艾克森美孚研究与工程公司 | 调控毒素和抗毒素基因用于生物防范 |
| US8951762B2 (en) | 2011-07-27 | 2015-02-10 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| US9399768B2 (en) | 2011-07-27 | 2016-07-26 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| DE102011110945A1 (de) | 2011-08-15 | 2013-02-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt |
| DE102011110946A1 (de) | 2011-08-15 | 2016-01-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen |
| CN103975070A (zh) | 2011-09-27 | 2014-08-06 | 艾克森美孚研究与工程公司 | 酰基-酰基载体蛋白(acyl-acp)蜡酯合酶 |
| PT2814972T (pt) | 2012-02-24 | 2020-06-16 | Exxonmobil Res & Eng Co | Produção melhorada de ácidos gordos e derivados de ácidos gordos por micro-organismos recombinantes |
| US9096834B2 (en) | 2012-02-24 | 2015-08-04 | Exxonmobil Research And Engineering Company | Recombinant microorganisms comprising thioesterase and lysophosphatidic acid acyltransferase genes for fatty acid production |
| US8962299B2 (en) | 2012-02-29 | 2015-02-24 | Exxonmobil Research And Engineering Company | Four-gene pathway for wax ester synthesis |
| BR112014025719A8 (pt) | 2012-04-18 | 2017-10-03 | Solazyme Inc | Óleos customizados |
| US9719114B2 (en) | 2012-04-18 | 2017-08-01 | Terravia Holdings, Inc. | Tailored oils |
| US9181568B2 (en) | 2012-04-23 | 2015-11-10 | Exxonmobil Research And Engineering Company | Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases |
| WO2014088560A1 (en) * | 2012-12-04 | 2014-06-12 | Exxonmobil Research And Engineering Company | Tetraselmis promoters and terminators for use in eukaryotic cells |
| US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
| US9249252B2 (en) | 2013-04-26 | 2016-02-02 | Solazyme, Inc. | Low polyunsaturated fatty acid oils and uses thereof |
| DE102013208228A1 (de) | 2013-05-06 | 2014-11-06 | Siemens Aktiengesellschaft | Verfahren zum Kultivieren eines Mikroorganismus in einer in vitro Kultur und Verfahren zum Herstellen eines Sekundärmetabolits |
| FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
| MX369685B (es) | 2013-10-04 | 2019-11-19 | Terravia Holdings Inc | Aceites adaptables. |
| JP6341676B2 (ja) | 2014-01-31 | 2018-06-13 | 花王株式会社 | 改変シアノバクテリア |
| WO2015149026A1 (en) | 2014-03-28 | 2015-10-01 | Solazyme, Inc. | Lauric ester compositions |
| EP3620517A3 (en) | 2014-07-10 | 2020-07-29 | Corbion Biotech, Inc. | Ketoacyl acp synthase genes and uses thereof |
| KR101735632B1 (ko) * | 2014-12-10 | 2017-05-16 | 한국과학기술연구원 | 시아노박테리아 발현 벡터 |
| JP6663856B2 (ja) * | 2014-12-22 | 2020-03-13 | 花王株式会社 | 改変シアノバクテリア |
| JP6568718B2 (ja) | 2015-05-22 | 2019-08-28 | 花王株式会社 | 脂質の製造方法 |
| JP6587468B2 (ja) * | 2015-09-11 | 2019-10-09 | 花王株式会社 | 脂質の製造方法 |
| WO2017120473A1 (en) | 2016-01-07 | 2017-07-13 | Conagen Inc. | Methods of making capsinoids by biosynthetic processes |
| US10418697B2 (en) * | 2016-02-25 | 2019-09-17 | Toshiba Client Solutions Co. Ltd. | Antenna apparatus and electronic device |
| JP6734112B2 (ja) * | 2016-05-10 | 2020-08-05 | 花王株式会社 | 脂質の製造方法 |
| US11459591B2 (en) | 2016-07-19 | 2022-10-04 | Conagen Inc. | Method for the microbial production of specific natural capsaicinoids |
| JP6971607B2 (ja) * | 2016-12-19 | 2021-11-24 | 花王株式会社 | 脂質の製造方法 |
| WO2018119343A1 (en) * | 2016-12-22 | 2018-06-28 | Conagen Inc. | Method for the microbial production of 8-methyl nonanoic acid |
| JP6934303B2 (ja) | 2017-02-08 | 2021-09-15 | 花王株式会社 | 脂肪族アルコールの生産方法 |
| EP3794017A4 (en) | 2018-05-17 | 2022-03-09 | Lumen Bioscience, Inc. | ARTHROSPIRA PLATENSIS ORAL VACCINE DELIVERY PLATFORM |
| US12252513B2 (en) | 2018-07-16 | 2025-03-18 | Lumen Bioscience, Inc. | Thermostable phycobiliproteins produced from recombinant arthrospira |
| JP7551990B2 (ja) * | 2020-08-28 | 2024-09-18 | 大成建設株式会社 | 遊離脂肪酸の分離方法と回収方法 |
| US11336975B1 (en) | 2021-02-01 | 2022-05-17 | Shure Acquisition Holdings, Inc. | Wearable device with detune-resilient antenna |
| JP7646964B2 (ja) * | 2021-08-20 | 2025-03-18 | 大成建設株式会社 | 遊離脂肪酸の回収方法、回収システム |
| GB2617381A (en) | 2022-04-07 | 2023-10-11 | Phycobloom Ltd | Engineered photosynthetic organisms |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5298421A (en) * | 1990-04-26 | 1994-03-29 | Calgene, Inc. | Plant medium-chain-preferring acyl-ACP thioesterases and related methods |
| US5179219A (en) * | 1990-11-19 | 1993-01-12 | Uop | Process for separating fatty acids and triglycerides |
| US5455167A (en) | 1991-05-21 | 1995-10-03 | Calgene Inc. | Medium-chain thioesterases in plants |
| JP2729883B2 (ja) * | 1992-10-07 | 1998-03-18 | 工業技術院長 | 藍藻を用いる有機分泌物の製造方法 |
| US6150512A (en) * | 1995-05-15 | 2000-11-21 | Yuan; Ling | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| DK0963439T3 (da) | 1997-02-19 | 2007-09-03 | Enol Energy Inc | Genmanipulerede Cyanobakterier til fremstilling af ethanol |
| US6495140B1 (en) * | 1998-01-12 | 2002-12-17 | Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada | Process for the isolation, recovery and purification of non-polar extractives |
| EP1197560A4 (en) * | 1999-07-07 | 2005-08-03 | Kyowa Hakko Kogyo Kk | PROCESS FOR PREPARING HYDROXILATED FATTY ACID AND DELTA LACTONE |
| PL207026B1 (pl) * | 2000-02-09 | 2010-10-29 | Basf Ag | Wyizolowany kwas nukleinowy, konstrukt genowy zawierający ten kwas, sekwencja aminokwasowa kodowana przez wyizolowaną sekwencję tego kwasu nukleinowego, wektor zawierający kwas nukleinowy lub konstrukt genowy, roślina transgeniczna lub mikroorganizm transgeniczny zawierający kwas nukleinowy, konstrukt genowy lub wektor, przeciwciało specyficznie wiążące się z polipeptydem kodowanym przez kwas nukleinowy, cząsteczka antysensownego kwasu nukleinowego oraz sposób wytwarzania wielonienasyconych kwasów tłuszczowych (PUFA) |
| ES2343106T3 (es) * | 2000-09-28 | 2010-07-23 | BIORIGINAL FOOD & SCIENCE CORP. | Fad4, fad5, fad5-2 y fad6, miembros de la familia de desaturasas de acidos grasos y usos de los mismos. |
| AU2005214874B2 (en) * | 2004-02-13 | 2010-02-18 | Martek Biosciences Corporation | Schizochytrium fatty acid synthase (FAS) and products and methods related thereto |
| EP1752532A1 (en) | 2005-08-09 | 2007-02-14 | Helmholtz-Zentrum für Infektionsforschung GmbH | Extracellular polyhydroxyalkanoates produced by genetically engineered microorganisms |
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US7470532B2 (en) * | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| JP5933909B2 (ja) * | 2006-05-19 | 2016-06-15 | アールイージー ライフ サイエンシズ リミテッド ライアビリティ カンパニー | 脂肪酸およびその誘導体の生産 |
| CA3178593A1 (en) | 2007-03-28 | 2008-10-02 | Genomatica, Inc. | Enhanced production of fatty acid derivatives |
| JP2010528627A (ja) | 2007-06-01 | 2010-08-26 | ソラザイム、インク | 微生物による油の生産 |
| BRPI0821508B1 (pt) | 2007-12-11 | 2018-12-26 | Synthetic Genomics Inc | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| US20110218354A1 (en) | 2008-09-19 | 2011-09-08 | President And Fellows Of Harvard College | Photoautotrophic Adipogenesis Technology (Phat) |
-
2008
- 2008-12-11 BR BRPI0821508A patent/BRPI0821508B1/pt not_active IP Right Cessation
- 2008-12-11 EP EP08860168.7A patent/EP2231864B1/en not_active Not-in-force
- 2008-12-11 AU AU2008335089A patent/AU2008335089B2/en not_active Ceased
- 2008-12-11 WO PCT/US2008/086485 patent/WO2009076559A1/en not_active Ceased
- 2008-12-11 CN CN200880126568.0A patent/CN101952452B/zh not_active Expired - Fee Related
- 2008-12-11 JP JP2010538169A patent/JP5465183B2/ja not_active Expired - Fee Related
- 2008-12-11 US US12/333,280 patent/US20090298143A1/en not_active Abandoned
- 2008-12-11 MY MYPI2010002698A patent/MY154028A/en unknown
- 2008-12-11 MX MX2010006539A patent/MX2010006539A/es unknown
-
2010
- 2010-06-15 ZA ZA2010/04253A patent/ZA201004253B/en unknown
-
2011
- 2011-12-29 US US13/340,350 patent/US10233470B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2231864A1 (en) | 2010-09-29 |
| EP2231864B1 (en) | 2017-05-24 |
| JP2011505838A (ja) | 2011-03-03 |
| US20090298143A1 (en) | 2009-12-03 |
| AU2008335089A1 (en) | 2009-06-18 |
| MY154028A (en) | 2015-04-30 |
| AU2008335089B2 (en) | 2014-06-26 |
| US10233470B2 (en) | 2019-03-19 |
| WO2009076559A8 (en) | 2010-05-20 |
| JP5465183B2 (ja) | 2014-04-09 |
| ZA201004253B (en) | 2011-08-31 |
| BRPI0821508B1 (pt) | 2018-12-26 |
| US20130005003A1 (en) | 2013-01-03 |
| BRPI0821508A2 (pt) | 2014-11-04 |
| CN101952452A (zh) | 2011-01-19 |
| CN101952452B (zh) | 2014-07-09 |
| EP2231864A4 (en) | 2011-02-02 |
| WO2009076559A1 (en) | 2009-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2010006539A (es) | Secrecion de acidos grasos por parte de microorganismos fotosinteticos. | |
| KR101780799B1 (ko) | 재조합 종속영양성 미생물에서 맞춤 오일의 제조 | |
| EP2448955B1 (en) | Acyl-acp thioesterase genes and uses therefor | |
| EP2478089B1 (en) | Microalgae fermentation using controlled illumination | |
| AU2013249172B2 (en) | Tailored oils | |
| JP2018099138A (ja) | 組み換え油産生微生物から生成される用途に応じた油 | |
| KR20150113973A (ko) | 변이체 티오에스테라제 및 사용 방법 | |
| AU2012316749A1 (en) | Acyl-ACP wax ester synthases | |
| WO2016164495A1 (en) | Oleaginous microalgae having an lpaat ablation | |
| Ohlrogge et al. | The seeds of green energy: expanding the contribution of plant oils as biofuels |