JP2022043100A5 - - Google Patents
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- Publication number
- JP2022043100A5 JP2022043100A5 JP2021195994A JP2021195994A JP2022043100A5 JP 2022043100 A5 JP2022043100 A5 JP 2022043100A5 JP 2021195994 A JP2021195994 A JP 2021195994A JP 2021195994 A JP2021195994 A JP 2021195994A JP 2022043100 A5 JP2022043100 A5 JP 2022043100A5
- Authority
- JP
- Japan
- Prior art keywords
- activity
- fatty acid
- polypeptide
- recombinant microbial
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000694 effects Effects 0.000 claims 19
- 229920001184 polypeptide Polymers 0.000 claims 17
- 102000004196 processed proteins & peptides Human genes 0.000 claims 17
- 108090000765 processed proteins & peptides Proteins 0.000 claims 17
- 230000000813 microbial effect Effects 0.000 claims 14
- 235000014113 dietary fatty acids Nutrition 0.000 claims 10
- 229930195729 fatty acid Natural products 0.000 claims 10
- 239000000194 fatty acid Substances 0.000 claims 10
- 150000004665 fatty acids Chemical class 0.000 claims 10
- 102000040430 polynucleotide Human genes 0.000 claims 10
- 108091033319 polynucleotide Proteins 0.000 claims 10
- 239000002157 polynucleotide Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 7
- 229940053200 antiepileptics fatty acid derivative Drugs 0.000 claims 4
- QAQREVBBADEHPA-IEXPHMLFSA-N propionyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC)O[C@H]1N1C2=NC=NC(N)=C2N=C1 QAQREVBBADEHPA-IEXPHMLFSA-N 0.000 claims 4
- 108010019608 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase Proteins 0.000 claims 3
- 102100037149 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 3
- 102000007698 Alcohol dehydrogenase Human genes 0.000 claims 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 2
- 108010082340 Arginine deiminase Proteins 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- XFTRTWQBIOMVPK-UHFFFAOYSA-N (-)-(R)-2-hydroxy-2-methylbutanedioic acid Natural products OC(=O)C(O)(C)CC(O)=O XFTRTWQBIOMVPK-UHFFFAOYSA-N 0.000 claims 1
- 102100022089 Acyl-[acyl-carrier-protein] hydrolase Human genes 0.000 claims 1
- 102000004031 Carboxy-Lyases Human genes 0.000 claims 1
- 108090000489 Carboxy-Lyases Proteins 0.000 claims 1
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 1
- XFTRTWQBIOMVPK-RXMQYKEDSA-N D-citramalic acid Chemical compound OC(=O)[C@@](O)(C)CC(O)=O XFTRTWQBIOMVPK-RXMQYKEDSA-N 0.000 claims 1
- 101710088194 Dehydrogenase Proteins 0.000 claims 1
- 102000004195 Isomerases Human genes 0.000 claims 1
- 108090000769 Isomerases Proteins 0.000 claims 1
- 101710129019 Long-chain acyl-[acyl-carrier-protein] reductase Proteins 0.000 claims 1
- 102100037611 Lysophospholipase Human genes 0.000 claims 1
- 241000795633 Olea <sea slug> Species 0.000 claims 1
- 102000005488 Thioesterase Human genes 0.000 claims 1
- 230000002238 attenuated effect Effects 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 108090001018 hexadecanal dehydrogenase (acylating) Proteins 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 108020002982 thioesterase Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/232,927 | 2011-09-14 | ||
| US13/232,927 US8372610B2 (en) | 2010-09-15 | 2011-09-14 | Production of odd chain fatty acid derivatives in recombinant microbial cells |
| JP2019194213A JP7042785B2 (ja) | 2011-09-14 | 2019-10-25 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019194213A Division JP7042785B2 (ja) | 2011-09-14 | 2019-10-25 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022043100A JP2022043100A (ja) | 2022-03-15 |
| JP2022043100A5 true JP2022043100A5 (enExample) | 2022-05-31 |
Family
ID=58543708
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017011738A Expired - Fee Related JP6609274B2 (ja) | 2011-09-14 | 2017-01-26 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
| JP2019194213A Active JP7042785B2 (ja) | 2011-09-14 | 2019-10-25 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
| JP2021195994A Pending JP2022043100A (ja) | 2011-09-14 | 2021-12-02 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017011738A Expired - Fee Related JP6609274B2 (ja) | 2011-09-14 | 2017-01-26 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
| JP2019194213A Active JP7042785B2 (ja) | 2011-09-14 | 2019-10-25 | 組換え微生物細胞における奇数鎖脂肪酸誘導体の生成 |
Country Status (3)
| Country | Link |
|---|---|
| JP (3) | JP6609274B2 (enExample) |
| CN (1) | CN107365733B (enExample) |
| BR (1) | BR112014005938A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109266592A (zh) * | 2018-08-23 | 2019-01-25 | 天津科技大学 | 一种l-酪氨酸基因工程菌及其生产l-酪氨酸的方法 |
| CN112410389B (zh) * | 2019-08-23 | 2023-07-18 | 中国科学院微生物研究所 | 支链α-酮酸脱氢酶复合体在制备丙二酸单酰辅酶A中的应用 |
| WO2021168039A1 (en) * | 2020-02-19 | 2021-08-26 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Biofilm bioreactor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101490241A (zh) * | 2006-05-19 | 2009-07-22 | Ls9公司 | 脂肪酸及其衍生物的制备 |
| CA2678261A1 (en) * | 2007-02-09 | 2008-08-14 | The Regents Of The University Of California | Biofuel production by recombinant microorganisms |
| CA2704227A1 (en) * | 2007-11-10 | 2009-05-14 | Joule Biotechnologies, Inc. | Hyperphotosynthetic organisms |
-
2012
- 2012-03-08 BR BR112014005938A patent/BR112014005938A2/pt not_active IP Right Cessation
- 2012-03-08 CN CN201710682902.1A patent/CN107365733B/zh not_active Expired - Fee Related
-
2017
- 2017-01-26 JP JP2017011738A patent/JP6609274B2/ja not_active Expired - Fee Related
-
2019
- 2019-10-25 JP JP2019194213A patent/JP7042785B2/ja active Active
-
2021
- 2021-12-02 JP JP2021195994A patent/JP2022043100A/ja active Pending
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