|
US7884119B2
(en)
*
|
2005-09-07 |
2011-02-08 |
Rigel Pharmaceuticals, Inc. |
Triazole derivatives useful as Axl inhibitors
|
|
US8012965B2
(en)
|
2006-12-29 |
2011-09-06 |
Rigel Pharmaceuticals, Inc. |
Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
|
|
WO2008083353A1
(en)
*
|
2006-12-29 |
2008-07-10 |
Rigel Pharmaceuticals, Inc. |
Bicyclic aryl and bicyclic heteroaryl substituted triazoles useful as axl inhibitors
|
|
EP2078010B1
(en)
|
2006-12-29 |
2014-01-29 |
Rigel Pharmaceuticals, Inc. |
Polycyclic heteroaryl substituted triazoles useful as axl inhibitors
|
|
CA2710046C
(en)
*
|
2006-12-29 |
2016-02-09 |
Rigel Pharmaceuticals, Inc. |
N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as axl inhibitors
|
|
JP2010514810A
(ja)
|
2006-12-29 |
2010-05-06 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
Ａｘｌインヒビターとして有用な置換トリアゾール
|
|
EP2205592B1
(en)
*
|
2007-10-26 |
2013-05-08 |
Rigel Pharmaceuticals, Inc. |
Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as axl inhibitors
|
|
HUE030912T2
(en)
|
2008-02-15 |
2017-06-28 |
Rigel Pharmaceuticals Inc |
Pyrimidine-2-amine compounds and their use as inhibitors of yak kinases
|
|
ES2537480T3
(es)
|
2008-07-09 |
2015-06-08 |
Rigel Pharmaceuticals, Inc. |
Triazoles sustituidos con heteroarilo policíclicos útiles como inhibidores de Axl
|
|
JP5613156B2
(ja)
*
|
2008-07-09 |
2014-10-22 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
Ａｘｌ阻害剤として有用な架橋二環ヘテロアリール置換トリアゾール
|
|
JP4644273B2
(ja)
*
|
2008-07-15 |
2011-03-02 |
本田技研工業株式会社 |
車両周辺監視装置
|
|
PL2387395T3
(pl)
*
|
2009-01-16 |
2015-03-31 |
Rigel Pharmaceuticals Inc |
Inhibitory Axl do zastosowania w terapii skojarzonej do zapobiegania, leczenia lub postępowania z nowotworem przerzutowym
|
|
DK2810937T3
(en)
|
2012-01-31 |
2017-03-13 |
Daiichi Sankyo Co Ltd |
PYRIDONE DERIVATIVES
|
|
WO2013162061A1
(ja)
*
|
2012-04-26 |
2013-10-31 |
第一三共株式会社 |
二環性ピリミジン化合物
|
|
EP3184121A3
(en)
|
2012-07-25 |
2017-09-27 |
Salk Institute For Biological Studies |
Lipid membranes with exposed phosphatidylserine as tam ligands, use for treating autoimmune diseases
|
|
AU2014353006B2
(en)
|
2013-11-20 |
2019-04-04 |
Signalchem Life Sciences Corp. |
Quinazoline derivatives as TAM family kinase inhibitors
|
|
US10233176B2
(en)
|
2013-11-27 |
2019-03-19 |
Signalchem Lifesciences Corporation |
Aminopyridine derivatives as TAM family kinase inhibitors
|
|
TWI723572B
(zh)
*
|
2014-07-07 |
2021-04-01 |
日商第一三共股份有限公司 |
具有四氫吡喃基甲基之吡啶酮衍生物及其用途
|
|
US9840503B2
(en)
|
2015-05-11 |
2017-12-12 |
Incyte Corporation |
Heterocyclic compounds and uses thereof
|
|
GB201509338D0
(en)
|
2015-05-29 |
2015-07-15 |
Bergenbio As |
Combination therapy
|
|
US9708333B2
(en)
|
2015-08-12 |
2017-07-18 |
Incyte Corporation |
Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors
|
|
WO2017035366A1
(en)
|
2015-08-26 |
2017-03-02 |
Incyte Corporation |
Pyrrolopyrimidine derivatives as tam inhibitors
|
|
WO2017055484A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining the metabolic status of lymphomas
|
|
EP3400443B1
(en)
|
2016-01-04 |
2020-09-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
|
WO2017146236A1
(ja)
|
2016-02-26 |
2017-08-31 |
小野薬品工業株式会社 |
Ａｘｌ阻害剤と免疫チェックポイント阻害剤とを組み合わせて投与することを特徴とする癌治療のための医薬
|
|
KR102483020B1
(ko)
|
2016-03-28 |
2023-01-04 |
인사이트 코포레이션 |
Tam 저해제로서의 피롤로트리아진 화합물
|
|
US10713077B2
(en)
*
|
2017-01-26 |
2020-07-14 |
Semper Fortis Solutions, LLC |
Multiple single levels of security (MSLS) in a multi-tenant cloud
|
|
US20210186982A1
(en)
|
2017-03-24 |
2021-06-24 |
Universite Nice Sophia Antipolis |
Methods and compositions for treating melanoma
|
|
US20200197385A1
(en)
|
2017-08-23 |
2020-06-25 |
Ono Pharmaceutical Co., Ltd. |
Therapeutic agent for cancer containing axl inhibitor as active ingredient
|
|
MA50655B1
(fr)
|
2017-09-27 |
2021-11-30 |
Incyte Corp |
Sels de dérivés de pyrrolotriazine utiles en tant qu'inhibiteurs de tam
|
|
US11826363B2
(en)
|
2017-10-13 |
2023-11-28 |
Ono Pharmaceutical Co., Ltd. |
Therapeutic agent for solid cancers, which comprises Axl inhibitor as active ingredient
|
|
EP3735590A1
(en)
|
2018-01-04 |
2020-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
|
EP3756012A1
(en)
|
2018-02-21 |
2020-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
|
AR117600A1
(es)
|
2018-06-29 |
2021-08-18 |
Incyte Corp |
Formulaciones de un inhibidor de axl / mer
|
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
|
US20230183379A1
(en)
|
2018-11-20 |
2023-06-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
|
EP3898699A1
(en)
|
2018-12-19 |
2021-10-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
|
ES3033655T3
(en)
|
2019-01-30 |
2025-08-06 |
Inst Nat Sante Rech Med |
Methods and compositions for identifying whether a subject suffering from a cancer will achieve a response with an immune-checkpoint inhibitor
|
|
EP3921031A1
(en)
|
2019-02-04 |
2021-12-15 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for modulating blood-brain barrier
|
|
EP3924520A1
(en)
|
2019-02-13 |
2021-12-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
|
EA202192575A1
(ru)
|
2019-03-21 |
2022-01-14 |
Онксео |
Соединения dbait в сочетании с ингибиторами киназ для лечения рака
|
|
EP3963109A1
(en)
|
2019-04-30 |
2022-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
GB201912059D0
(en)
|
2019-08-22 |
2019-10-09 |
Bergenbio As |
Combaination therapy of a patient subgroup
|
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2021064180A1
(en)
|
2019-10-03 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
|
WO2021074391A1
(en)
|
2019-10-17 |
2021-04-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
|
EP4051286A1
(en)
|
2019-10-29 |
2022-09-07 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for treating uveal melanoma
|
|
CN114761006A
(zh)
|
2019-11-08 |
2022-07-15 |
Inserm(法国国家健康医学研究院) |
对激酶抑制剂产生耐药性的癌症的治疗方法
|
|
EP4076508A1
(en)
|
2019-12-19 |
2022-10-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
|
US20230076415A1
(en)
|
2020-01-17 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2021148581A1
(en)
|
2020-01-22 |
2021-07-29 |
Onxeo |
Novel dbait molecule and its use
|
|
EP4100126A1
(en)
|
2020-02-05 |
2022-12-14 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
|
WO2021170777A1
(en)
|
2020-02-28 |
2021-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
|
WO2021178779A1
(en)
|
2020-03-06 |
2021-09-10 |
Incyte Corporation |
Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors
|
|
GB202004189D0
(en)
|
2020-03-23 |
2020-05-06 |
Bergenbio As |
Combination therapy
|
|
EP4132652A1
(en)
|
2020-04-08 |
2023-02-15 |
BerGenBio ASA |
Axl inhibitors for antiviral therapy
|
|
GB202006072D0
(en)
|
2020-04-24 |
2020-06-10 |
Bergenbio Asa |
Method of selecting patients for treatment with cmbination therapy
|
|
US20230266332A1
(en)
|
2020-07-28 |
2023-08-24 |
Inserm (Institut National De La Santè Et De La Recherch Médicale) |
Methods and compositions for preventing and treating a cancer
|
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
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|
|
US20230416838A1
(en)
|
2020-11-16 |
2023-12-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
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|
|
US20230416830A1
(en)
|
2020-11-16 |
2023-12-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
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|
|
US20240165094A1
(en)
|
2021-03-17 |
2024-05-23 |
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|
|
GB202104037D0
(en)
|
2021-03-23 |
2021-05-05 |
Bergenbio Asa |
Combination therapy
|
|
EP4326903A1
(en)
|
2021-04-23 |
2024-02-28 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
|
US20240426823A1
(en)
|
2021-11-03 |
2024-12-26 |
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Methods and compositions for treating triple negative breast cancer (tnbc)
|
|
EP4452257A1
(en)
|
2021-12-21 |
2024-10-30 |
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|
|
GB202209285D0
(en)
|
2022-06-24 |
2022-08-10 |
Bergenbio Asa |
Dosage regimen for AXL inhibitor
|
|
EP4568670A1
(en)
|
2022-08-10 |
2025-06-18 |
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Sigmar1 ligand for the treatment of pancreatic cancer
|
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
|
WO2024051667A1
(zh)
*
|
2022-09-05 |
2024-03-14 |
南京正大天晴制药有限公司 |
具有axl抑制活性的取代三唑化合物
|
|
US20260061031A1
(en)
|
2022-09-14 |
2026-03-05 |
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|
|
EP4605000A1
(en)
|
2022-10-21 |
2025-08-27 |
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|
|
EP4689658A1
(en)
|
2023-03-28 |
2026-02-11 |
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|
|
WO2024231384A1
(en)
|
2023-05-10 |
2024-11-14 |
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Compositions for treating senescence related disease
|
|
EP4713371A1
(en)
|
2023-05-17 |
2026-03-25 |
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Anti-cathepsin-d antibodies
|
|
WO2024245951A1
(en)
|
2023-05-26 |
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|
|
WO2024256635A1
(en)
|
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|
|
WO2025068180A1
(en)
|
2023-09-25 |
2025-04-03 |
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|
|
WO2025073765A1
(en)
|
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|
|
WO2025078632A1
(en)
|
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|
|
WO2025132479A1
(en)
|
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|
|
WO2025132770A1
(en)
|
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|
|
WO2025210123A1
(en)
|
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|
|
WO2025219330A1
(en)
|
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|
|
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(en)
|
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|
|
WO2025247829A1
(en)
|
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|
|
WO2026013071A1
(en)
|
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|