JP2011209291A5 - - Google Patents

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JP2011209291A5
JP2011209291A5 JP2011128088A JP2011128088A JP2011209291A5 JP 2011209291 A5 JP2011209291 A5 JP 2011209291A5 JP 2011128088 A JP2011128088 A JP 2011128088A JP 2011128088 A JP2011128088 A JP 2011128088A JP 2011209291 A5 JP2011209291 A5 JP 2011209291A5
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Japan
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protein
alzheimer
precursor
differentially expressed
disease
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JP2011128088A
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Japanese (ja)
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JP2011209291A (ja
JP5893269B2 (ja
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Priority claimed from GBGB0421639.6A external-priority patent/GB0421639D0/en
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Publication of JP2011209291A5 publication Critical patent/JP2011209291A5/ja
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Publication of JP5893269B2 publication Critical patent/JP5893269B2/ja
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JP2011128088A 2004-09-29 2011-06-08 アルツハイマー病に関する方法及び組成物 Expired - Lifetime JP5893269B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0421639.6A GB0421639D0 (en) 2004-09-29 2004-09-29 Methods and compositions relating to alzheimer's disease
GB0421639.6 2004-09-29

Related Parent Applications (1)

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JP2007534083A Division JP5483816B2 (ja) 2004-09-29 2005-09-29 アルツハイマー病に関する方法及び組成物

Related Child Applications (1)

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JP2014159434A Division JP2014209132A (ja) 2004-09-29 2014-08-05 アルツハイマー病に関する方法及び組成物

Publications (3)

Publication Number Publication Date
JP2011209291A JP2011209291A (ja) 2011-10-20
JP2011209291A5 true JP2011209291A5 (https=) 2012-08-23
JP5893269B2 JP5893269B2 (ja) 2016-03-23

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JP2007534083A Expired - Lifetime JP5483816B2 (ja) 2004-09-29 2005-09-29 アルツハイマー病に関する方法及び組成物
JP2011128088A Expired - Lifetime JP5893269B2 (ja) 2004-09-29 2011-06-08 アルツハイマー病に関する方法及び組成物
JP2014159434A Pending JP2014209132A (ja) 2004-09-29 2014-08-05 アルツハイマー病に関する方法及び組成物

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JP2007534083A Expired - Lifetime JP5483816B2 (ja) 2004-09-29 2005-09-29 アルツハイマー病に関する方法及び組成物

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JP2014159434A Pending JP2014209132A (ja) 2004-09-29 2014-08-05 アルツハイマー病に関する方法及び組成物

Country Status (10)

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US (2) US7897361B2 (https=)
EP (3) EP2562545A1 (https=)
JP (3) JP5483816B2 (https=)
AT (1) ATE495445T1 (https=)
AU (1) AU2005288689B2 (https=)
CA (1) CA2580532C (https=)
DE (1) DE602005025897D1 (https=)
DK (1) DK2354795T3 (https=)
GB (1) GB0421639D0 (https=)
WO (1) WO2006035237A2 (https=)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0421639D0 (en) * 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease
GB0426859D0 (en) * 2004-12-07 2005-01-12 Proteome Sciences Plc Diagnosis of neurodegenerative disorders
GB2428240A (en) 2005-07-14 2007-01-24 Univ Gen Ve Diagnostic method for brain damage-related disorders
ES2543341T3 (es) 2005-09-13 2015-08-18 National Research Council Of Canada Métodos y composiciones para modular la actividad de células tumorales
GB0701626D0 (en) 2007-01-22 2007-03-07 Cambridge Entpr Ltd Methods and biomarkers for diagnosing and monitoring psychotic disorders
AT506819B1 (de) 2008-06-12 2011-06-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzin zur behandlung von alzheimer-krankheit
EP2344881A4 (en) * 2008-09-26 2012-03-07 Univ Melbourne BIOMARKER FOR MORBUS ALZHEIMER
IT1392551B1 (it) * 2008-11-25 2012-03-09 Bioindustry Park Del Canavese S P A Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica
US20120071337A1 (en) 2009-01-26 2012-03-22 Electrophoretics Limited Methods
JP2010271078A (ja) * 2009-05-19 2010-12-02 Mcbi:Kk 認知機能障害疾患を含む精神疾患のバイオマーカーおよび該バイオマーカーを用いた認知機能障害疾患を含む精神疾患の検出方法
AU2010202926B2 (en) * 2009-09-11 2016-07-14 Electrophoretics Limited Markers and methods relating to the assessment of Alzheimer's disease
EA034462B1 (ru) 2009-11-24 2020-02-11 Алетиа Байотерапьютикс Инк. Антикластериновые антитела и антигенсвязывающие фрагменты и их использование для уменьшения объема новообразований
JP6012923B2 (ja) * 2010-12-22 2016-10-25 株式会社Mcbi 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法
JP5906519B2 (ja) * 2011-09-13 2016-04-20 国立大学法人 熊本大学 二次元電気泳動による蛋白質の分離方法
JP2014533834A (ja) * 2011-11-18 2014-12-15 アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. トランスサイレチンおよびそのアイソフォームの定量化
US9822170B2 (en) 2012-02-22 2017-11-21 Alethia Biotherapeutics Inc. Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer
WO2013148166A1 (en) 2012-03-29 2013-10-03 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behlaf Of Arizona State University Nanoscale process to generate reagents selective for individual protein variants
USRE49625E1 (en) 2012-03-29 2023-08-29 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Nanoscale process to generate reagents selective for individual protein variants
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
US10501513B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides for the production of oncology-related proteins and peptides
WO2013151665A2 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
WO2013153461A2 (en) 2012-04-13 2013-10-17 Oasis Diagnostics Corporation Specific salivary biomarkers for risk detection, early diagnosis, prognosis and monitoring of alzheimer's and parkinson's diseases
WO2014040042A2 (en) 2012-09-10 2014-03-13 The Johns Hopkins University Diagnostic assay for alzheimer's disease
WO2014055683A1 (en) * 2012-10-03 2014-04-10 The Research Foundation For The State University Of New York Spectroscopic method for alzheimer's disease diagnosis
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
CA2902068C (en) * 2013-02-28 2023-10-03 Caprion Proteomics Inc. Tuberculosis biomarkers and uses thereof
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
GB201310203D0 (en) * 2013-06-07 2013-07-24 Electrophoretics Ltd Materials and methods relating to Alzheimer's disease
GB201310150D0 (en) * 2013-06-07 2013-07-24 Electrophoretics Ltd Methods and compositions relating to alzheimer's disease
EP3039431A4 (en) * 2013-08-27 2017-05-03 CRC for Mental Health Ltd. Method of identifying biomarkers of neurological diseases and diagnosis of neurological diseases
GB201322094D0 (en) 2013-12-13 2014-01-29 Electrophoretics Ltd Methods and compositions relating to alzheimers disease
CA2936056A1 (en) * 2014-01-06 2015-07-09 Children's Medical Center Corporation Biomarkers for dementia and dementia related neurological disorders
GB201403489D0 (en) * 2014-02-27 2014-04-16 Univ London Queen Mary Biomarkers for endometriosis
US10639322B2 (en) * 2015-03-27 2020-05-05 The Research Foundation For The State University Of New York Methods and materials for reducing amyloid beta levels within a mammal
US9904961B2 (en) 2015-05-07 2018-02-27 Kuwait University System and method for determining the feedback capacity of information distributed in a complex network
JP6193942B2 (ja) * 2015-09-09 2017-09-06 株式会社Mcbi 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法
CN105403649B (zh) * 2015-12-01 2018-03-20 深圳大学 一种检测ad的尿液多肽组ad生物标记物
JP6947451B2 (ja) * 2016-06-29 2021-10-13 学校法人自治医科大学 バイオマーカー、診断用組成物、及び診断用キット
JP6947450B2 (ja) * 2016-06-29 2021-10-13 学校法人自治医科大学 バイオマーカー、診断用組成物、及び診断用キット
WO2019013341A1 (ja) * 2017-07-14 2019-01-17 株式会社島津製作所 疾患検出方法
JP6408087B2 (ja) * 2017-07-25 2018-10-17 株式会社Mcbi 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
CN113024651A (zh) * 2019-12-25 2021-06-25 中国医学科学院药物研究所 阿尔茨海默病生物标志物及其应用
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
US20220260559A1 (en) * 2020-11-04 2022-08-18 Seer, Inc. Biomarkers for diagnosing alzheimer's disease
CN115808492A (zh) * 2021-09-14 2023-03-17 中国科学院深圳先进技术研究院 一种阿尔兹海默症生物标志物天冬酰胺及其应用
EP4605754A1 (en) * 2022-10-18 2025-08-27 Immungenetics AG Identifying a subject suffering from alzheimer's dementia or being at risk of developing alzheimer's dementia
CN117831756B (zh) * 2024-03-05 2024-06-28 精智未来(广州)智能科技有限公司 一种认知障碍的辅助分析方法、装置、设备及存储介质

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US6342350B1 (en) * 1997-09-05 2002-01-29 The General Hospital Corporation Alpha-2-macroglobulin diagnostic test
US20030211622A1 (en) 1998-06-29 2003-11-13 Roberts L. Jackson Methods and compositions to assess oxidative brain injury
US20030131364A1 (en) * 1999-04-27 2003-07-10 Karen Duff Method for producing transgenic animal models with modulated phenotype and animals produced therefrom
JP2001249128A (ja) * 2000-03-06 2001-09-14 Ikagaku:Kk 動脈硬化症またはアルツハイマー病の診断用キット
US20020174447A1 (en) * 2001-01-23 2002-11-21 Greenspan Ralph J. Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease
US6528309B2 (en) * 2001-03-19 2003-03-04 The Regents Of The University Of California Vacuum-mediated desiccation protection of cells
US6451547B1 (en) * 2001-04-25 2002-09-17 Syn X Pharma Process for differential diagnosis of Alzheimer's dementia and device therefor
DE10158180A1 (de) * 2001-11-28 2003-09-11 Biovision Ag Verfahren zum Nachweis von Morbus Alzheimer und zur Unterscheidung von Morbus Alzheimer gegenüber anderen demenziellen Erkrankungen, zugehörige Peptide und deren Verwendung
WO2004001421A2 (en) * 2002-06-21 2003-12-31 Innogenetics N.V. Method for the diagnosis and differential diagnosis of neurological diseases
US20070128596A1 (en) * 2002-07-03 2007-06-07 Roninson Igor B Reagents and methods for identifying and modulating expression of tumor senescence genes
WO2004030522A2 (en) * 2002-10-02 2004-04-15 Dmi Biosciences, Inc. Diagnosis and monitoring of diseases
KR100595494B1 (ko) * 2003-02-24 2006-07-03 (주) 디지탈바이오텍 혈액 내 베타-아밀로이드 항체 농도를 이용한 알츠하이머병 진단키트
GB0421639D0 (en) * 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease

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