DE602005025897D1 - Verfahren und zusammensetzungen in verbindung mit morbus alzheimer - Google Patents
Verfahren und zusammensetzungen in verbindung mit morbus alzheimerInfo
- Publication number
- DE602005025897D1 DE602005025897D1 DE602005025897T DE602005025897T DE602005025897D1 DE 602005025897 D1 DE602005025897 D1 DE 602005025897D1 DE 602005025897 T DE602005025897 T DE 602005025897T DE 602005025897 T DE602005025897 T DE 602005025897T DE 602005025897 D1 DE602005025897 D1 DE 602005025897D1
- Authority
- DE
- Germany
- Prior art keywords
- alzheimer
- disease
- compositions
- connection
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0421639.6A GB0421639D0 (en) | 2004-09-29 | 2004-09-29 | Methods and compositions relating to alzheimer's disease |
PCT/GB2005/003756 WO2006035237A2 (en) | 2004-09-29 | 2005-09-29 | Methods and compositions relating to alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005025897D1 true DE602005025897D1 (de) | 2011-02-24 |
Family
ID=33397455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005025897T Active DE602005025897D1 (de) | 2004-09-29 | 2005-09-29 | Verfahren und zusammensetzungen in verbindung mit morbus alzheimer |
Country Status (10)
Country | Link |
---|---|
US (2) | US7897361B2 (de) |
EP (3) | EP1794594B1 (de) |
JP (3) | JP5483816B2 (de) |
AT (1) | ATE495445T1 (de) |
AU (1) | AU2005288689B2 (de) |
CA (1) | CA2580532C (de) |
DE (1) | DE602005025897D1 (de) |
DK (1) | DK2354795T3 (de) |
GB (1) | GB0421639D0 (de) |
WO (1) | WO2006035237A2 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0421639D0 (en) * | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
GB0426859D0 (en) * | 2004-12-07 | 2005-01-12 | Proteome Sciences Plc | Diagnosis of neurodegenerative disorders |
GB2428240A (en) | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
EP1937815B1 (de) | 2005-09-13 | 2015-05-13 | National Research Council of Canada | Verfahren und zusammensetzungen zur modulation der tumorzellaktivität |
GB0701626D0 (en) | 2007-01-22 | 2007-03-07 | Cambridge Entpr Ltd | Methods and biomarkers for diagnosing and monitoring psychotic disorders |
AT506819B1 (de) * | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
AU2009295357A1 (en) * | 2008-09-26 | 2010-04-01 | The University Of Melbourne | Alzheimer's disease biomarkers |
IT1392551B1 (it) * | 2008-11-25 | 2012-03-09 | Bioindustry Park Del Canavese S P A | Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica |
JP5755149B2 (ja) * | 2009-01-26 | 2015-07-29 | エレクトロフォレティクス リミテッドElectrophoretics Limited | 方法 |
JP2010271078A (ja) * | 2009-05-19 | 2010-12-02 | Mcbi:Kk | 認知機能障害疾患を含む精神疾患のバイオマーカーおよび該バイオマーカーを用いた認知機能障害疾患を含む精神疾患の検出方法 |
CA2709621A1 (en) * | 2009-09-11 | 2011-03-11 | Electrophoretics Limited | Markers and methods relating to the assessment of alzheimer's disease |
DK2504363T3 (da) | 2009-11-24 | 2019-07-29 | Alethia Biotherapeutics Inc | Anti-clusterin-antistoffer og antigenbindende fragmenter og deres anvendelse til reducering af tumorvolumen |
JP6012923B2 (ja) * | 2010-12-22 | 2016-10-25 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法 |
JP5906519B2 (ja) * | 2011-09-13 | 2016-04-20 | 国立大学法人 熊本大学 | 二次元電気泳動による蛋白質の分離方法 |
WO2013074861A1 (en) * | 2011-11-18 | 2013-05-23 | Alnylam Pharmaceuticals, Inc. | Quantification of transthyretin and its isoforms |
MX2014010164A (es) | 2012-02-22 | 2014-11-25 | Alethia Biotherapeutics Inc | Co-uso de un inhibidor de clusterina con un inhibidor de egfr para tratar cancer. |
CA2868777A1 (en) | 2012-03-29 | 2013-10-03 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Nanoscale process to generate reagents selective for individual protein variants |
USRE49625E1 (en) | 2012-03-29 | 2023-08-29 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona | Nanoscale process to generate reagents selective for individual protein variants |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US10501513B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides for the production of oncology-related proteins and peptides |
AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
CA2877975C (en) | 2012-04-13 | 2021-09-21 | Oasis Diagnostics Corporation | Specific salivary biomarkers for risk detection, early diagnosis, prognosis and monitoring of alzheimer's and parkinson's diseases |
WO2014040042A2 (en) | 2012-09-10 | 2014-03-13 | The Johns Hopkins University | Diagnostic assay for alzheimer's disease |
WO2014055683A1 (en) * | 2012-10-03 | 2014-04-10 | The Research Foundation For The State University Of New York | Spectroscopic method for alzheimer's disease diagnosis |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
JP6416793B2 (ja) * | 2013-02-28 | 2018-10-31 | カプリオン プロテオミクス インコーポレーテッド | 結核のバイオマーカー及びその使用 |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
GB201310203D0 (en) | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Materials and methods relating to Alzheimer's disease |
GB201310150D0 (en) | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Methods and compositions relating to alzheimer's disease |
AU2014311258B2 (en) * | 2013-08-27 | 2020-12-17 | Crc For Mental Health Ltd | Method of identifying biomarkers of neurological diseases and diagnosis of neurological diseases |
GB201322094D0 (en) | 2013-12-13 | 2014-01-29 | Electrophoretics Ltd | Methods and compositions relating to alzheimers disease |
US20160327572A1 (en) * | 2014-01-06 | 2016-11-10 | Children's Medical Center Corporation | Biomarkers for Dementia and Dementia Related Neurological Disorders |
GB201403489D0 (en) * | 2014-02-27 | 2014-04-16 | Univ London Queen Mary | Biomarkers for endometriosis |
US10639322B2 (en) * | 2015-03-27 | 2020-05-05 | The Research Foundation For The State University Of New York | Methods and materials for reducing amyloid beta levels within a mammal |
US9904961B2 (en) | 2015-05-07 | 2018-02-27 | Kuwait University | System and method for determining the feedback capacity of information distributed in a complex network |
JP6193942B2 (ja) * | 2015-09-09 | 2017-09-06 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法 |
CN105403649B (zh) * | 2015-12-01 | 2018-03-20 | 深圳大学 | 一种检测ad的尿液多肽组ad生物标记物 |
JP6947451B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
JP6947450B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
JPWO2019013341A1 (ja) * | 2017-07-14 | 2020-07-09 | 株式会社Mcbi | 疾患検出方法 |
JP6408087B2 (ja) * | 2017-07-25 | 2018-10-17 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法 |
CN113024651A (zh) * | 2019-12-25 | 2021-06-25 | 中国医学科学院药物研究所 | 阿尔茨海默病生物标志物及其应用 |
US20220260559A1 (en) * | 2020-11-04 | 2022-08-18 | Seer, Inc. | Biomarkers for diagnosing alzheimer's disease |
WO2024083822A1 (en) * | 2022-10-18 | 2024-04-25 | Immungenetics Ag | Identifying a subject suffering from alzheimer's dementia or being at risk of developing alzheimer's dementia |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
US6342350B1 (en) * | 1997-09-05 | 2002-01-29 | The General Hospital Corporation | Alpha-2-macroglobulin diagnostic test |
US20030211622A1 (en) | 1998-06-29 | 2003-11-13 | Roberts L. Jackson | Methods and compositions to assess oxidative brain injury |
US20030131364A1 (en) | 1999-04-27 | 2003-07-10 | Karen Duff | Method for producing transgenic animal models with modulated phenotype and animals produced therefrom |
JP2001249128A (ja) * | 2000-03-06 | 2001-09-14 | Ikagaku:Kk | 動脈硬化症またはアルツハイマー病の診断用キット |
US20020174447A1 (en) | 2001-01-23 | 2002-11-21 | Greenspan Ralph J. | Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease |
US6528309B2 (en) * | 2001-03-19 | 2003-03-04 | The Regents Of The University Of California | Vacuum-mediated desiccation protection of cells |
US6451547B1 (en) * | 2001-04-25 | 2002-09-17 | Syn X Pharma | Process for differential diagnosis of Alzheimer's dementia and device therefor |
DE10158180A1 (de) * | 2001-11-28 | 2003-09-11 | Biovision Ag | Verfahren zum Nachweis von Morbus Alzheimer und zur Unterscheidung von Morbus Alzheimer gegenüber anderen demenziellen Erkrankungen, zugehörige Peptide und deren Verwendung |
WO2004001421A2 (en) * | 2002-06-21 | 2003-12-31 | Innogenetics N.V. | Method for the diagnosis and differential diagnosis of neurological diseases |
WO2004005462A2 (en) * | 2002-07-03 | 2004-01-15 | The Board Of Trustees Of The University Of Illinois | Reagents and methods for identifying and modulating expression of tumor senescence genes |
CA2500652A1 (en) * | 2002-10-02 | 2004-04-15 | Dmi Biosciences, Inc. | Diagnosis and monitoring of diseases |
WO2004074837A1 (en) * | 2003-02-24 | 2004-09-02 | Digitalbiotech Co., Ltd. | Method for measuring the level of anti-beta-amyloid antibody in body fluids and diagnostic kit for alzheimer’s disease using same |
GB0421639D0 (en) * | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
-
2004
- 2004-09-29 GB GBGB0421639.6A patent/GB0421639D0/en not_active Ceased
-
2005
- 2005-09-29 CA CA2580532A patent/CA2580532C/en active Active
- 2005-09-29 EP EP05788728A patent/EP1794594B1/de active Active
- 2005-09-29 DE DE602005025897T patent/DE602005025897D1/de active Active
- 2005-09-29 EP EP10010288.8A patent/EP2354795B1/de active Active
- 2005-09-29 DK DK10010288.8T patent/DK2354795T3/en active
- 2005-09-29 US US11/664,076 patent/US7897361B2/en active Active
- 2005-09-29 AU AU2005288689A patent/AU2005288689B2/en active Active
- 2005-09-29 WO PCT/GB2005/003756 patent/WO2006035237A2/en active Application Filing
- 2005-09-29 JP JP2007534083A patent/JP5483816B2/ja active Active
- 2005-09-29 EP EP12191625A patent/EP2562545A1/de not_active Withdrawn
- 2005-09-29 AT AT05788728T patent/ATE495445T1/de not_active IP Right Cessation
-
2011
- 2011-01-12 US US13/005,121 patent/US20110165146A1/en not_active Abandoned
- 2011-06-08 JP JP2011128088A patent/JP5893269B2/ja active Active
-
2014
- 2014-08-05 JP JP2014159434A patent/JP2014209132A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK2354795T3 (en) | 2015-02-16 |
EP2562545A1 (de) | 2013-02-27 |
CA2580532C (en) | 2019-06-25 |
WO2006035237A3 (en) | 2006-08-03 |
GB0421639D0 (en) | 2004-10-27 |
JP5893269B2 (ja) | 2016-03-23 |
EP1794594A2 (de) | 2007-06-13 |
US20080070995A1 (en) | 2008-03-20 |
JP5483816B2 (ja) | 2014-05-07 |
EP1794594B1 (de) | 2011-01-12 |
WO2006035237A2 (en) | 2006-04-06 |
JP2011209291A (ja) | 2011-10-20 |
US20110165146A1 (en) | 2011-07-07 |
EP2354795B1 (de) | 2014-12-17 |
CA2580532A1 (en) | 2006-04-06 |
AU2005288689A1 (en) | 2006-04-06 |
JP2014209132A (ja) | 2014-11-06 |
AU2005288689B2 (en) | 2011-10-27 |
EP2354795A1 (de) | 2011-08-10 |
JP2008514946A (ja) | 2008-05-08 |
US7897361B2 (en) | 2011-03-01 |
ATE495445T1 (de) | 2011-01-15 |
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