JP2011182720A5 - - Google Patents

Info

Publication number

JP2011182720A5

JP2011182720A5 JP2010052384A JP2010052384A JP2011182720A5 JP 2011182720 A5 JP2011182720 A5 JP 2011182720A5 JP 2010052384 A JP2010052384 A JP 2010052384A JP 2010052384 A JP2010052384 A JP 2010052384A JP 2011182720 A5 JP2011182720 A5 JP 2011182720A5

Authority

JP

Japan

Prior art keywords

positive

stem cells

vasa

oct4

germline stem

Prior art date

2010-03-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 210000001368 germline stem cell Anatomy 0.000 claims 15
• 238000000034 method Methods 0.000 claims 12
• 210000001778 pluripotent stem cell Anatomy 0.000 claims 9
• 102000034615 Glial cell line-derived neurotrophic factor Human genes 0.000 claims 7
• 108091010837 Glial cell line-derived neurotrophic factor Proteins 0.000 claims 7
• 210000004027 cell Anatomy 0.000 claims 7
• VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 claims 6
• 108010049955 Bone Morphogenetic Protein 4 Proteins 0.000 claims 5
• 102100024505 Bone morphogenetic protein 4 Human genes 0.000 claims 5
• 102000009024 Epidermal Growth Factor Human genes 0.000 claims 5
• 101800003838 Epidermal growth factor Proteins 0.000 claims 5
• 239000003795 chemical substances by application Substances 0.000 claims 5
• 229940116977 epidermal growth factor Drugs 0.000 claims 5
• 239000003102 growth factor Substances 0.000 claims 4
• 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 3
• 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 3
• 102000003957 Fibroblast growth factor 9 Human genes 0.000 claims 3
• 108090000367 Fibroblast growth factor 9 Proteins 0.000 claims 3
• 102000003745 Hepatocyte Growth Factor Human genes 0.000 claims 3
• 108090000100 Hepatocyte Growth Factor Proteins 0.000 claims 3
• 108010002350 Interleukin-2 Proteins 0.000 claims 3
• 102100020873 Interleukin-2 Human genes 0.000 claims 3
• 238000012258 culturing Methods 0.000 claims 3
• 230000004069 differentiation Effects 0.000 claims 3
• 230000003321 amplification Effects 0.000 claims 2
• 239000000411 inducer Substances 0.000 claims 2
• 238000003199 nucleic acid amplification method Methods 0.000 claims 2
• 208000007466 Male Infertility Diseases 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 239000001963 growth medium Substances 0.000 claims 1
• 230000001939 inductive effect Effects 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 239000002609 medium Substances 0.000 claims 1
• 210000000130 stem cell Anatomy 0.000 claims 1
• 229940124597 therapeutic agent Drugs 0.000 claims 1