JP2011168588A5 - - Google Patents
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- JP2011168588A5 JP2011168588A5 JP2011026980A JP2011026980A JP2011168588A5 JP 2011168588 A5 JP2011168588 A5 JP 2011168588A5 JP 2011026980 A JP2011026980 A JP 2011026980A JP 2011026980 A JP2011026980 A JP 2011026980A JP 2011168588 A5 JP2011168588 A5 JP 2011168588A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- compound
- apoptosis inducer
- test compound
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011026980A JP5213972B2 (ja) | 2004-04-09 | 2011-02-10 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004115404 | 2004-04-09 | ||
| JP2004115404 | 2004-04-09 | ||
| JP2011026980A JP5213972B2 (ja) | 2004-04-09 | 2011-02-10 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006512126A Division JP4761389B2 (ja) | 2004-04-09 | 2005-04-08 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012046652A Division JP5390653B2 (ja) | 2004-04-09 | 2012-03-02 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011168588A JP2011168588A (ja) | 2011-09-01 |
| JP2011168588A5 true JP2011168588A5 (https=) | 2012-04-19 |
| JP5213972B2 JP5213972B2 (ja) | 2013-06-19 |
Family
ID=35124844
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006512126A Expired - Fee Related JP4761389B2 (ja) | 2004-04-09 | 2005-04-08 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
| JP2011026980A Expired - Fee Related JP5213972B2 (ja) | 2004-04-09 | 2011-02-10 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
| JP2012046652A Expired - Fee Related JP5390653B2 (ja) | 2004-04-09 | 2012-03-02 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006512126A Expired - Fee Related JP4761389B2 (ja) | 2004-04-09 | 2005-04-08 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012046652A Expired - Fee Related JP5390653B2 (ja) | 2004-04-09 | 2012-03-02 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8193332B2 (https=) |
| EP (4) | EP2520652B1 (https=) |
| JP (3) | JP4761389B2 (https=) |
| KR (1) | KR101234281B1 (https=) |
| WO (1) | WO2005097189A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4299299B2 (ja) * | 2003-05-19 | 2009-07-22 | 株式会社ジーンケア研究所 | 癌細胞に対するアポトーシス誘導剤 |
| EP2520652B1 (en) | 2004-04-09 | 2015-06-10 | Genecare Research Institute Co., Ltd | Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associates genes |
| KR101330229B1 (ko) * | 2004-11-19 | 2013-11-15 | 가부시키가이샤 진케어켄큐쇼 | 암세포 특이적 세포증식 억제제 |
| EP1846550A2 (en) * | 2005-02-10 | 2007-10-24 | Centre National De La Recherche Scientifique (Cnrs) | Use of the mcm8 gene for the preparation of a pharmaceutical composition |
| EP1915622A2 (en) * | 2005-07-29 | 2008-04-30 | Oncotherapy Science, Inc. | Screening and therapeutic method for nsclc targeting cdca1-kntc2 complex |
| GB0606096D0 (en) | 2006-03-27 | 2006-05-03 | Cbmm Sa | Screening method |
| WO2008047574A1 (fr) * | 2006-09-28 | 2008-04-24 | Genecare Research Institute Co., Ltd. | Sensibilisateur pour agent anticancéreux |
| JP4940412B2 (ja) * | 2006-10-16 | 2012-05-30 | 財団法人ヒューマンサイエンス振興財団 | 抗癌性物質のスクリーニング方法 |
| CA2666584A1 (en) * | 2006-10-17 | 2008-04-24 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
| TWI596109B (zh) * | 2007-02-21 | 2017-08-21 | 腫瘤療法 科學股份有限公司 | 表現腫瘤相關抗原之癌症的胜肽疫苗 |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| WO2010034487A2 (en) * | 2008-09-23 | 2010-04-01 | Silence Therapeutics Ag | Means for inhibiting the expression of orc-1 |
| WO2010045526A1 (en) * | 2008-10-17 | 2010-04-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Geminin inhibitors as tumor treatment |
| US20110237649A1 (en) * | 2008-12-04 | 2011-09-29 | Opko Curna, Llc | Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirtuin 1 |
| WO2010102058A2 (en) * | 2009-03-04 | 2010-09-10 | Curna, Inc. | Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt 1 |
| US8435961B2 (en) * | 2009-06-26 | 2013-05-07 | Massachusetts Institute Of Technology | Methods and compositions for increasing the activity of inhibitory RNA |
| WO2010151664A2 (en) | 2009-06-26 | 2010-12-29 | Massachusetts Institute Of Technology | Compositions and methods for treating cancer and modulating stress granule formation |
| US8268550B2 (en) * | 2009-06-26 | 2012-09-18 | Massachusetts Institute Of Technology | Compositions and methods for identification of PARP function, inhibitors, and activators |
| ES2854004T3 (es) * | 2009-07-24 | 2021-09-20 | Curna Inc | Tratamiento de enfermedades relacionadas con Sirtuina 6 (SIRT6) mediante inhibición del transcrito antisentido natural para SIRT6 |
| SG183304A1 (en) | 2010-02-17 | 2012-09-27 | Takeda Pharmaceutical | Heterocyclic compound |
| WO2011150418A2 (en) * | 2010-05-28 | 2011-12-01 | Case Western Reserve University | Compositions and methods for treating pathologies |
| WO2012090479A1 (en) * | 2010-12-28 | 2012-07-05 | Oncotherapy Science, Inc. | Mcm7 as a target gene for cancer therapy and diagnosis |
| CA2868302A1 (en) | 2012-03-23 | 2013-09-26 | Dennis M. Brown | Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo |
| ES2872967T3 (es) | 2012-06-29 | 2021-11-03 | Celgene Corp | Métodos para determinar la eficacia de fármacos usando IKZF3 (AIOLOS) |
| US9512486B2 (en) * | 2012-08-06 | 2016-12-06 | The Institute Of Cancer Research: Royal Cancer Hospital | Materials, methods, and systems for treating cancer |
| TWI658049B (zh) | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Kntc2胜肽及含此胜肽之疫苗 |
| KR101623814B1 (ko) | 2014-02-21 | 2016-05-24 | 두산중공업 주식회사 | 수냉각 발전기의 분리형 냉각수 순환 구조 및 그에 따른 냉각 방법 |
| JP2015167527A (ja) * | 2014-03-07 | 2015-09-28 | 学校法人東京理科大学 | 標的タンパク質の量の低減のためのポリペプチド、単離された核酸、組み換えベクター、及び形質転換体 |
| WO2016102517A1 (en) * | 2014-12-23 | 2016-06-30 | Centre National De La Recherche Scientifique | Use of rad18 inhibitors in the treatment of tumors |
| CN104673801B (zh) * | 2015-02-12 | 2018-09-11 | 中山大学附属第三医院 | 一种肝癌基因ndc80及其应用 |
| JP6854246B2 (ja) | 2015-06-08 | 2021-04-07 | アーケア ダイアグノスティクス リミテッド | 尿サンプルの分析方法 |
| EP3304084B1 (en) | 2015-06-08 | 2022-03-23 | Arquer Diagnostics Limited | Methods and kits |
| WO2018053035A1 (en) * | 2016-09-13 | 2018-03-22 | The Jackson Laboratory | Targeted dna demethylation and methylation |
| WO2018079287A1 (ja) * | 2016-10-26 | 2018-05-03 | デンカ株式会社 | 変異型ヒトDNAポリメラーゼε |
| WO2019005754A1 (en) * | 2017-06-26 | 2019-01-03 | The Cleveland Clinic Foundation | TREATMENT AGAINST CANCER |
| EP3851528A4 (en) * | 2018-09-12 | 2023-12-06 | Institute for Basic Science | COMPOSITION FOR INDUCATING DEATH OF CELLS HAVING MUTATED GENE AND METHOD FOR INDUCATING DEATH OF CELLS HAVING MODIFIED GENE USING THE COMPOSITION |
| JP2022020872A (ja) * | 2020-06-01 | 2022-02-02 | 均 石井 | 抗がん剤。 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0923738A1 (en) * | 1996-06-11 | 1999-06-23 | Advanced Research & Technology Institute | Methods and compositions for the use of apurinic/apyrimidinic endonucleases |
| GB0004193D0 (en) * | 2000-02-22 | 2000-04-12 | Isis Innovation | A genetic determinant for malignant melanoma |
| US6773883B2 (en) * | 2000-07-31 | 2004-08-10 | The Brigham & Women's Hospital, Inc. | Prognostic classification of endometrial cancer |
| CA2429814C (en) | 2000-12-01 | 2014-02-18 | Thomas Tuschl | Rna interference mediating small rna molecules |
| US7892730B2 (en) * | 2000-12-22 | 2011-02-22 | Sagres Discovery, Inc. | Compositions and methods for cancer |
| WO2002102981A2 (en) * | 2001-06-15 | 2002-12-27 | The Trustees Of Columbia University In The City Of New York | SIR2α-BASED THERAPEUTIC AND PROPHYLACTIC METHODS |
| AU2002362030A1 (en) * | 2001-11-27 | 2003-06-10 | Fred Hutchinson Cancer Research Center | Methods for inhibiting deacetylase activity |
| EP1432724A4 (en) * | 2002-02-20 | 2006-02-01 | Sirna Therapeutics Inc | RNA inhibition mediated inhibition of MAP KINASE GENES |
| AU2003250831A1 (en) * | 2002-06-12 | 2003-12-31 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Use of hec1 antagonists in the treatment of proliferative disorders and cancer |
| WO2004033666A2 (en) * | 2002-10-11 | 2004-04-22 | Board Of Regents, The University Of Texas System | Method and compounds for inhibiting hec1 activity for the treatment of proliferative diseases |
| AU2003295600A1 (en) * | 2002-11-14 | 2004-06-15 | Dharmacon, Inc. | Functional and hyperfunctional sirna |
| JP2006523456A (ja) * | 2003-04-15 | 2006-10-19 | アバロン ファーマシューティカルズ,インコーポレイテッド | 分子細胞遺伝学的方法を用いる癌連鎖遺伝子および治療標的の確認 |
| WO2004094636A1 (en) * | 2003-04-24 | 2004-11-04 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| JP4299299B2 (ja) | 2003-05-19 | 2009-07-22 | 株式会社ジーンケア研究所 | 癌細胞に対するアポトーシス誘導剤 |
| EP2520652B1 (en) | 2004-04-09 | 2015-06-10 | Genecare Research Institute Co., Ltd | Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associates genes |
| KR101330229B1 (ko) | 2004-11-19 | 2013-11-15 | 가부시키가이샤 진케어켄큐쇼 | 암세포 특이적 세포증식 억제제 |
-
2005
- 2005-04-08 EP EP12005593.4A patent/EP2520652B1/en not_active Expired - Lifetime
- 2005-04-08 KR KR1020067023433A patent/KR101234281B1/ko not_active Expired - Fee Related
- 2005-04-08 US US11/547,770 patent/US8193332B2/en not_active Expired - Fee Related
- 2005-04-08 EP EP12004228.8A patent/EP2495324B1/en not_active Expired - Lifetime
- 2005-04-08 JP JP2006512126A patent/JP4761389B2/ja not_active Expired - Fee Related
- 2005-04-08 EP EP12003008.5A patent/EP2481802B1/en not_active Expired - Lifetime
- 2005-04-08 EP EP05728503A patent/EP1757306A4/en not_active Withdrawn
- 2005-04-08 WO PCT/JP2005/006914 patent/WO2005097189A1/ja not_active Ceased
-
2011
- 2011-02-10 JP JP2011026980A patent/JP5213972B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-02 JP JP2012046652A patent/JP5390653B2/ja not_active Expired - Fee Related
- 2012-05-16 US US13/473,328 patent/US8470798B2/en not_active Expired - Fee Related
-
2013
- 2013-05-22 US US13/900,380 patent/US8703930B2/en not_active Expired - Fee Related
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