JP2014221834A5 - - Google Patents
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- Publication number
- JP2014221834A5 JP2014221834A5 JP2014167336A JP2014167336A JP2014221834A5 JP 2014221834 A5 JP2014221834 A5 JP 2014221834A5 JP 2014167336 A JP2014167336 A JP 2014167336A JP 2014167336 A JP2014167336 A JP 2014167336A JP 2014221834 A5 JP2014221834 A5 JP 2014221834A5
- Authority
- JP
- Japan
- Prior art keywords
- mir
- tumor
- level
- subject
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12032208P | 2008-12-05 | 2008-12-05 | |
| US61/120,322 | 2008-12-05 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539777A Division JP2012511031A (ja) | 2008-12-05 | 2009-12-07 | miR−31に関連する組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014221834A JP2014221834A (ja) | 2014-11-27 |
| JP2014221834A5 true JP2014221834A5 (https=) | 2015-02-19 |
| JP6110346B2 JP6110346B2 (ja) | 2017-04-05 |
Family
ID=42233912
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539777A Pending JP2012511031A (ja) | 2008-12-05 | 2009-12-07 | miR−31に関連する組成物および方法 |
| JP2014167336A Expired - Fee Related JP6110346B2 (ja) | 2008-12-05 | 2014-08-20 | miR−31に関連する組成物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539777A Pending JP2012511031A (ja) | 2008-12-05 | 2009-12-07 | miR−31に関連する組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20120041048A1 (https=) |
| EP (1) | EP2370091B1 (https=) |
| JP (2) | JP2012511031A (https=) |
| AU (1) | AU2009322137B2 (https=) |
| CA (1) | CA2745919A1 (https=) |
| WO (1) | WO2010065961A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013033794A2 (pt) * | 2011-06-27 | 2019-09-24 | Medimmune Llc | uso de uma quantidade eficaz de uma composição, e, método para avaliar a presença, ausência ou quantidade de um biomarcador |
| CN102776191A (zh) * | 2012-07-20 | 2012-11-14 | 苏州大学 | 一种微小rna用于调控cd86的基因表达 |
| WO2015033565A1 (ja) * | 2013-09-06 | 2015-03-12 | 国立大学法人東京大学 | 癌の診断、阻害剤のスクリーニングにおけるrhoaの使用 |
| EP3134522B1 (en) | 2014-04-25 | 2021-10-06 | University of Massachusetts | Recombinant aav vectors useful for reducing immunity against transgene products |
| EP3444362B1 (en) * | 2014-05-02 | 2020-12-09 | Ruprecht-Karls-Universität Heidelberg | Circulating mirnas as early detection marker and prognostic marker |
| US9623040B2 (en) * | 2014-07-14 | 2017-04-18 | The Board Of Trustees Of The Leland Stanford Junior University | Immunomodulation by controlling expression levels of microRNAs in dendritic cells |
| WO2016054554A1 (en) | 2014-10-03 | 2016-04-07 | University Of Massachusetts | Heterologous targeting peptide grafted aavs |
| WO2016131009A1 (en) | 2015-02-13 | 2016-08-18 | University Of Massachusetts | Compositions and methods for transient delivery of nucleases |
| WO2018183594A1 (en) * | 2017-03-29 | 2018-10-04 | Children's Hospital Medical Center | Nucleic acid molecules and their methods of use |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1726199A (en) * | 1997-12-31 | 1999-07-19 | Chiron Corporation | Metastatic cancer regulated gene |
| JP2002527066A (ja) * | 1998-10-15 | 2002-08-27 | カイロン コーポレイション | 転移性乳癌および結腸癌調節遺伝子 |
| JP2006519008A (ja) * | 2003-02-10 | 2006-08-24 | 独立行政法人産業技術総合研究所 | 哺乳動物細胞の調節 |
| US20080014579A1 (en) * | 2003-02-11 | 2008-01-17 | Affymetrix, Inc. | Gene expression profiling in colon cancers |
| US20050193432A1 (en) | 2003-11-18 | 2005-09-01 | Whitehead Institute For Biomedical Research | Xenograft model of functional normal and malignant human breast tissues in rodents and methods thereof |
| WO2005113770A1 (en) * | 2004-05-13 | 2005-12-01 | Institut Gustave Roussy | Anti-rhoa and -rhoc sirnas and therapeutic compositions comprising them. |
| CA2857881A1 (en) * | 2004-11-12 | 2006-12-28 | Asuragen, Inc. | Methods and compositions involving mirna and mirna inhibitor molecules |
| WO2006061430A2 (en) * | 2004-12-10 | 2006-06-15 | Proskelia | Bone metastasis markers as a target regulating bone metastasis and bone development |
| US7666595B2 (en) * | 2005-02-25 | 2010-02-23 | The Brigham And Women's Hospital, Inc. | Biomarkers for predicting prostate cancer progression |
| US20070213292A1 (en) | 2005-08-10 | 2007-09-13 | The Rockefeller University | Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof |
| US8445198B2 (en) * | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| EP2487258B1 (en) * | 2006-01-05 | 2014-10-01 | The Ohio State University Research Foundation | MicroRNA-based methods for the diagnosis of colon, pancreas and stomach cancer |
| US20080199961A1 (en) | 2006-08-25 | 2008-08-21 | Avi Biopharma, Inc. | ANTISENSE COMPOSITION AND METHOD FOR INHIBITION OF miRNA BIOGENESIS |
| JP2010510964A (ja) * | 2006-09-19 | 2010-04-08 | アシュラジェン インコーポレイテッド | 治療的介入の標的としての、miR−15、miR−26、miR−31、miR−145、miR−147、miR−188、miR−215、miR−216、miR−331、mmu−miR−292−3pによって調節される遺伝子および経路 |
| WO2009070767A2 (en) | 2007-11-28 | 2009-06-04 | Whitehead Institute For Biomedical Research | Systemic instigation systems to study tumor growth or metastasis |
| WO2009075787A1 (en) * | 2007-12-05 | 2009-06-18 | The Johns Hopkins University | Compositions and methods of treating neoplasia |
| US20130065949A1 (en) * | 2009-10-14 | 2013-03-14 | Baylor College Of Medicine | Microrna mirna-31 as a therapeutic approach for the treatment of cancer |
| US20140322705A1 (en) * | 2010-08-20 | 2014-10-30 | Thomas Jefferson University | Cancer diagnostic and cancer therapeutic |
-
2009
- 2009-12-07 EP EP09831269.7A patent/EP2370091B1/en not_active Not-in-force
- 2009-12-07 WO PCT/US2009/067015 patent/WO2010065961A2/en not_active Ceased
- 2009-12-07 US US13/132,917 patent/US20120041048A1/en not_active Abandoned
- 2009-12-07 AU AU2009322137A patent/AU2009322137B2/en not_active Ceased
- 2009-12-07 CA CA2745919A patent/CA2745919A1/en not_active Abandoned
- 2009-12-07 JP JP2011539777A patent/JP2012511031A/ja active Pending
-
2014
- 2014-01-08 US US14/150,518 patent/US20140343121A1/en not_active Abandoned
- 2014-08-20 JP JP2014167336A patent/JP6110346B2/ja not_active Expired - Fee Related
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