JP2011126894A5 - - Google Patents

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Publication number
JP2011126894A5
JP2011126894A5 JP2011017553A JP2011017553A JP2011126894A5 JP 2011126894 A5 JP2011126894 A5 JP 2011126894A5 JP 2011017553 A JP2011017553 A JP 2011017553A JP 2011017553 A JP2011017553 A JP 2011017553A JP 2011126894 A5 JP2011126894 A5 JP 2011126894A5
Authority
JP
Japan
Prior art keywords
azithromycin
monohydrate
organic solvent
stable
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011017553A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011126894A (ja
Filing date
Publication date
Priority claimed from GBGB9915218.3A external-priority patent/GB9915218D0/en
Priority claimed from GBGB9915216.7A external-priority patent/GB9915216D0/en
Priority claimed from GBGB9930059.2A external-priority patent/GB9930059D0/en
Application filed filed Critical
Publication of JP2011126894A publication Critical patent/JP2011126894A/ja
Publication of JP2011126894A5 publication Critical patent/JP2011126894A5/ja
Pending legal-status Critical Current

Links

JP2011017553A 1999-06-29 2011-01-31 マクロライド Pending JP2011126894A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9915218.3 1999-06-29
GB9915216.7 1999-06-29
GBGB9915218.3A GB9915218D0 (en) 1999-06-29 1999-06-29 Organic compounds
GBGB9915216.7A GB9915216D0 (en) 1999-06-29 1999-06-29 Organic compounds
GB9930059.2 1999-12-20
GBGB9930059.2A GB9930059D0 (en) 1999-12-20 1999-12-20 Organic compounds

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2001507048A Division JP4703924B2 (ja) 1999-06-29 2000-06-27 マクロライド

Publications (2)

Publication Number Publication Date
JP2011126894A JP2011126894A (ja) 2011-06-30
JP2011126894A5 true JP2011126894A5 (enrdf_load_stackoverflow) 2012-03-01

Family

ID=27269768

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001507048A Expired - Fee Related JP4703924B2 (ja) 1999-06-29 2000-06-27 マクロライド
JP2011017553A Pending JP2011126894A (ja) 1999-06-29 2011-01-31 マクロライド

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2001507048A Expired - Fee Related JP4703924B2 (ja) 1999-06-29 2000-06-27 マクロライド

Country Status (10)

Country Link
US (1) US6703372B1 (enrdf_load_stackoverflow)
EP (2) EP1189915B1 (enrdf_load_stackoverflow)
JP (2) JP4703924B2 (enrdf_load_stackoverflow)
KR (1) KR100700475B1 (enrdf_load_stackoverflow)
AT (2) ATE334136T1 (enrdf_load_stackoverflow)
AU (1) AU5820400A (enrdf_load_stackoverflow)
DE (3) DE60029589T2 (enrdf_load_stackoverflow)
ES (2) ES2267549T3 (enrdf_load_stackoverflow)
HR (1) HRP20010956B1 (enrdf_load_stackoverflow)
WO (1) WO2001000640A1 (enrdf_load_stackoverflow)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) * 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
CA2417353C (en) 2000-07-25 2009-09-01 Laboratorio Silanes,S.A. De C.V. Single-step process for preparing 7,16-deoxy-2-aza-10-o-cladinosil-12-o-desosaminil-4,5-dihydroxi-6-ethyl-3,5,9,11,13,15-hexamethylbicycle (11.2.1)hexadeca-1(2)-en-8-one, and obtaining a new form of 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin a
ES2172417B1 (es) * 2000-07-31 2003-09-16 Sint Quimica Sa Nueva forma mejorada de azitromicina monohidrato de menor higroscopicidad, procedimiento de preparacion y composiciones farmaceuticas que la comprenden.
SK287814B6 (sk) 2000-11-27 2011-11-04 Sandoz Ag Azithromycin in the form of a monohydrate, a process for its preparation and pharmaceutical compositions comprising same
HRP20010301A2 (en) * 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
KR100574153B1 (ko) 2001-05-22 2006-04-25 화이자 프로덕츠 인코포레이티드 아지트로마이신의 결정형
EP1671979B1 (en) * 2001-05-22 2008-08-13 Pfizer Products Inc. New Cristal Form of Azithromycin
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
BR0215175A (pt) * 2001-12-21 2004-12-28 Pfizer Prod Inc Métodos para a granulação úmida de azitromicina
EP1479687A4 (en) * 2002-02-26 2006-01-04 Meiji Seika Kaisha A NEW LOW-GYLIC CYCLIC AZALIDE, A NEW 16-LOW CYCLIC DIAZALID DERIVATIVE AND METHOD FOR THE PRODUCTION THEREOF
JP2005522470A (ja) * 2002-04-03 2005-07-28 ハンミ ファーム． シーオー．， エルティーディー． アジスロマイシンの製造方法及びそれに用いられる９−デオキソ−９ａ−アザ−９ａ−ホモエリスロマイシンＡの結晶性水和物
ITMI20021209A1 (it) * 2002-06-04 2003-12-04 Chemi Spa Processo di preparazione di azitromicina ad elevata purezza
GB0214277D0 (en) * 2002-06-20 2002-07-31 Biochemie Gmbh Organic compounds
US6855813B2 (en) 2002-07-19 2005-02-15 Alembic Limited Process for the preparation of azithromycin monohydrate
HRP20020614A2 (en) 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
GB0224197D0 (en) * 2002-10-17 2002-11-27 Biochemie Gmbh Organic compounds
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
DE602004019288D1 (de) * 2003-07-24 2009-03-19 Pliva Hrvatska D O O Schnellösliches azithromycin in einzeldosisform
US20060189800A1 (en) * 2003-07-24 2006-08-24 Mitsuru Ohkubo Indolopyrrolocabazole derivative and antitumor agent
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7683162B2 (en) * 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
WO2006055663A2 (en) * 2004-11-17 2006-05-26 Smithkline Beecham Corporation The use of novel antibacterial compounds
CN101177441B (zh) * 2007-12-05 2012-05-23 浙江耐司康药业有限公司 一种稳定的阿奇霉素一水合物结晶的制备方法
CN101445532B (zh) * 2008-12-30 2011-09-21 广东东阳光药业有限公司 阿奇霉素一水合物结晶的制备方法
EP2405909A1 (en) 2009-03-13 2012-01-18 Da Volterra Compositions and methods for elimination of gram-negative bacteria
CN102417531B (zh) * 2011-12-20 2014-06-11 浙江国邦药业有限公司 一种阿奇霉素一水合物的制备方法
CN105030704B (zh) * 2015-06-29 2018-09-07 石药集团欧意药业有限公司 阿奇霉素片剂及其制备方法
CN110684056B (zh) * 2018-07-05 2021-07-13 青岛农业大学 一种阿奇霉素中间体的化学合成方法
CN114516895A (zh) * 2020-11-19 2022-05-20 江苏威奇达药业有限公司 一种阿奇霉素胺结晶方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA835204B (en) * 1982-07-19 1985-02-27 Pfizer N-methyl 11-aza-10-deoxo-10-dihydroerythromycin a,intermediates therefor and processes for their preparation
MX12213A (es) * 1987-07-09 1993-05-01 Pfizer Metodo de preparacion de dihidrato de azitromicina cristalino
ES2122905B1 (es) * 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
GB9705323D0 (en) * 1997-03-14 1997-04-30 Biochemie Sa Organic compounds
PT994889E (pt) * 1997-07-08 2004-10-29 Biochemie Sa Solvatos de oxima de eritromicina a
PT102130A (pt) * 1998-03-13 1999-09-30 Hovione Sociedade Quimica S A Processo de preparacao de dihidrato de azitromicina
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
GB9824580D0 (en) * 1998-11-10 1999-01-06 Biochemie Sa Organic compounds

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