JP2011004665A5 - - Google Patents
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- Publication number
- JP2011004665A5 JP2011004665A5 JP2009151726A JP2009151726A JP2011004665A5 JP 2011004665 A5 JP2011004665 A5 JP 2011004665A5 JP 2009151726 A JP2009151726 A JP 2009151726A JP 2009151726 A JP2009151726 A JP 2009151726A JP 2011004665 A5 JP2011004665 A5 JP 2011004665A5
- Authority
- JP
- Japan
- Prior art keywords
- particles
- saponification
- pva
- degree
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 description 12
- 238000007127 saponification reaction Methods 0.000 description 11
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 2
- KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 150000000180 1,2-diols Chemical class 0.000 description 1
- 238000005160 1H NMR spectroscopy Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000012066 reaction slurry Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009151726A JP5612279B2 (ja) | 2009-06-26 | 2009-06-26 | 心筋梗塞非ヒト動物モデル及びその作製方法 |
| PCT/JP2010/060420 WO2010150715A1 (ja) | 2009-06-26 | 2010-06-21 | 心筋梗塞非ヒト動物モデル及びその作製方法 |
| EP10792033.2A EP2446739A4 (en) | 2009-06-26 | 2010-06-21 | NON-MENTAL ANIMAL MODEL FOR MYOCARDIAL INFARTS AND CONSTRUCTION PROCESSES THEREFOR |
| US13/288,158 US20120110683A1 (en) | 2009-06-26 | 2011-11-03 | Non-human animal model of myocardial infarction and method for creating the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009151726A JP5612279B2 (ja) | 2009-06-26 | 2009-06-26 | 心筋梗塞非ヒト動物モデル及びその作製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011004665A JP2011004665A (ja) | 2011-01-13 |
| JP2011004665A5 true JP2011004665A5 (cg-RX-API-DMAC7.html) | 2012-05-31 |
| JP5612279B2 JP5612279B2 (ja) | 2014-10-22 |
Family
ID=43386484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009151726A Expired - Fee Related JP5612279B2 (ja) | 2009-06-26 | 2009-06-26 | 心筋梗塞非ヒト動物モデル及びその作製方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20120110683A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2446739A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5612279B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010150715A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247218B (zh) * | 2011-03-25 | 2013-05-22 | 杨碧波 | 动物心力衰竭诱导装置 |
| KR101893150B1 (ko) | 2012-06-12 | 2018-08-30 | 엘지전자 주식회사 | 전력량측정장치가 내장된 가전기기 |
| JP6557683B2 (ja) | 2014-06-12 | 2019-08-07 | ティーエックス メディック エービー | 被験体において血管新生を誘導するための１００００ｄａ未満の平均分子量を有するデキストラン硫酸の使用 |
| CN106536056B (zh) | 2014-06-13 | 2021-07-16 | 儿童医学中心公司 | 分离线粒体的产品和方法 |
| US11903974B2 (en) | 2015-11-30 | 2024-02-20 | Flagship Pioneering Innovations V, Inc. | Methods and compositions relating to chondrisomes from cultured cells |
| WO2017124037A1 (en) * | 2016-01-15 | 2017-07-20 | The Children's Medical Center Corporation | Therapeutic use of mitochondria and combined mitochondrial agents |
| CN110198704A (zh) * | 2016-11-07 | 2019-09-03 | 默克专利股份有限公司 | 基于聚乙烯醇的控释片剂及其制备 |
| JP2019533001A (ja) * | 2016-11-07 | 2019-11-14 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 加熱溶融押出されたポリビニルアルコールを基にする瞬間放出カプセル |
| CN108182680B (zh) * | 2017-12-28 | 2021-12-28 | 中科微光医疗研究中心(西安)有限公司 | 一种基于ivoct图像的分叉血管的角度自动识别方法 |
| CN108090900B (zh) * | 2017-12-28 | 2021-12-28 | 中科微光医疗研究中心(西安)有限公司 | 一种基于ivoct图像的分叉血管自动识别方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56120707A (en) | 1980-02-29 | 1981-09-22 | Nippon Synthetic Chem Ind Co Ltd:The | Preparation of particulate polyvinyl alcohol |
| US5795331A (en) * | 1994-01-24 | 1998-08-18 | Micro Therapeutics, Inc. | Balloon catheter for occluding aneurysms of branch vessels |
| WO1998003203A1 (fr) | 1996-07-19 | 1998-01-29 | Yamanouchi Pharmaceutical Co., Ltd. | Particules poreuses insolubles dans l'eau, constituees de substances biocompatibles et leur procede de production |
| US6538026B1 (en) * | 1997-09-11 | 2003-03-25 | Provasis Therapeutics, Inc. | Compositions useful for remodeling body spaces |
| US6074407A (en) * | 1997-10-14 | 2000-06-13 | Target Therapeutics, Inc. | Delivery catheter for occlusive implants |
| JP4945039B2 (ja) | 2000-09-27 | 2012-06-06 | 武田薬品工業株式会社 | 心不全モデル動物の作製方法 |
| JP2002209473A (ja) | 2001-01-19 | 2002-07-30 | Yamaguchi Technology Licensing Organization Ltd | 広範囲心筋梗塞病態モデル動物及びその作成方法並びにそのモデル動物を用いて行う薬物のスクリーニング方法 |
| JP4686970B2 (ja) | 2002-10-29 | 2011-05-25 | 東レ株式会社 | 血管塞栓材料 |
| JP2005229927A (ja) | 2004-02-20 | 2005-09-02 | Yamaguchi Technology Licensing Organization Ltd | 分離心筋梗塞モデルを応用した心筋再生方法 |
| US20080295189A1 (en) * | 2004-09-13 | 2008-11-27 | Japan Health Sciences Foundation | Construction of Arterial Occlusive Disease Animal Model |
| JP4694812B2 (ja) | 2004-09-29 | 2011-06-08 | 日本合成化学工業株式会社 | 記録用媒体 |
| US8361454B2 (en) * | 2005-07-01 | 2013-01-29 | The Nippon Synthetic Chemical Industry Co., Ltd. | PVA particle for temporary embolic material and production process thereof, and temporary embolic material |
| JP5121172B2 (ja) | 2005-07-01 | 2013-01-16 | 日本合成化学工業株式会社 | 血管一時塞栓材料、その製造方法、および血管一時塞栓剤 |
-
2009
- 2009-06-26 JP JP2009151726A patent/JP5612279B2/ja not_active Expired - Fee Related
-
2010
- 2010-06-21 WO PCT/JP2010/060420 patent/WO2010150715A1/ja not_active Ceased
- 2010-06-21 EP EP10792033.2A patent/EP2446739A4/en not_active Withdrawn
-
2011
- 2011-11-03 US US13/288,158 patent/US20120110683A1/en not_active Abandoned