JP2010540438A5

JP2010540438A5 -

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Publication number: JP2010540438A5
Authority: JP; Japan
Prior art keywords: alk; haloalk; phenyl; heteroaryl; compound
Prior art date: 2008-09-19
Legal status : Pending

Application number

JP2010525834A

Other languages

English (en)

Japanese (ja)

Other versions

JP2010540438A (ja

Filing date

2008-09-19

Publication date

2011-10-20

2008-09-19 Application filed filed Critical

2008-09-19 Priority claimed from PCT/US2008/010887 external-priority patent/WO2009038759A2/en

2010-12-24 Publication of JP2010540438A publication Critical patent/JP2010540438A/ja

2011-10-20 Publication of JP2010540438A5 publication Critical patent/JP2010540438A5/ja

Status Pending legal-status Critical Current

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239000000203 mixture Substances 0.000 claims description 142
150000001875 compounds Chemical class 0.000 claims description 141
229910052799 carbon Inorganic materials 0.000 claims description 54
125000001072 heteroaryl group Chemical group 0.000 claims description 50
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229910052736 halogen Inorganic materials 0.000 claims description 48
150000002367 halogens Chemical class 0.000 claims description 48
229910052739 hydrogen Inorganic materials 0.000 claims description 48
-1 1H-tetrazol-5-yl Chemical group 0.000 claims description 44
229910052717 sulfur Inorganic materials 0.000 claims description 44
239000001257 hydrogen Substances 0.000 claims description 42
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 41
125000001424 substituent group Chemical group 0.000 claims description 36
229910052760 oxygen Inorganic materials 0.000 claims description 35
229910052794 bromium Inorganic materials 0.000 claims description 34
229910052801 chlorine Inorganic materials 0.000 claims description 34
229910052731 fluorine Inorganic materials 0.000 claims description 34
125000003118 aryl group Chemical group 0.000 claims description 32
238000002360 preparation method Methods 0.000 claims description 31
238000011282 treatment Methods 0.000 claims description 29
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JP2010525834A 2007-09-20 2008-09-19 免疫障害を処置するためのｓ１ｐ受容体調節剤としての１−（４−ベンジルベンズアミド）−ベンジル）アゼチジン−３−カルボン酸誘導体および関連化合物 Pending JP2010540438A (ja)