ES2360929T3 - Derivados del ácido 1-(4-(4-bencilbenzamido)-bencil)azetidin-3-carboxílico y compuestos relacionados como moduladores del receptor s1p para el tratamiento de trastornos inmunitarios. - Google Patents
Derivados del ácido 1-(4-(4-bencilbenzamido)-bencil)azetidin-3-carboxílico y compuestos relacionados como moduladores del receptor s1p para el tratamiento de trastornos inmunitarios. Download PDFInfo
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- ES2360929T3 ES2360929T3 ES08831946T ES08831946T ES2360929T3 ES 2360929 T3 ES2360929 T3 ES 2360929T3 ES 08831946 T ES08831946 T ES 08831946T ES 08831946 T ES08831946 T ES 08831946T ES 2360929 T3 ES2360929 T3 ES 2360929T3
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- alkyl
- haloalkyl
- phenyl
- heteroaryl
- hydrogen
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Landscapes
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| US7919519B2 (en) | 2005-11-23 | 2011-04-05 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
| CA2630714C (en) | 2005-11-23 | 2014-01-14 | Epix Delaware, Inc. | S1p receptor modulating compounds and use thereof |
| US7790707B2 (en) | 2006-03-21 | 2010-09-07 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
| US20090069288A1 (en) * | 2007-07-16 | 2009-03-12 | Breinlinger Eric C | Novel therapeutic compounds |
| US8080542B2 (en) | 2007-09-20 | 2011-12-20 | Amgen, Inc. | S1P receptor modulating compounds and use thereof |
| TW201000099A (en) * | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
| US8791100B2 (en) * | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| EP2643303A1 (en) | 2010-11-24 | 2013-10-02 | Allergan, Inc. | Modulators of s1p receptors |
| FR3017867A1 (fr) * | 2014-02-21 | 2015-08-28 | Inventiva | Nouveaux composes de type phenylazetidine carboxylate ou carboxamide |
| US9718771B2 (en) | 2014-02-28 | 2017-08-01 | Kissei Pharmaceutical Co., Ltd. | Aniline derivative, pharmaceutical composition containing same, and use thereof |
| US9895324B2 (en) | 2014-03-26 | 2018-02-20 | University Of Kentucky Research Foundation | Halogenated diarylacetylenes and methods of treating cancer |
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| ES2928856T3 (es) | 2015-11-19 | 2022-11-23 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
| WO2017106634A1 (en) | 2015-12-17 | 2017-06-22 | Incyte Corporation | N-phenyl-pyridine-2-carboxamide derivatives and their use as pd-1/pd-l1 protein/protein interaction modulators |
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- 2008-09-19 JP JP2010525834A patent/JP2010540438A/ja active Pending
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| MX2010002885A (es) | 2010-04-01 |
| JP2010540438A (ja) | 2010-12-24 |
| AU2008302746A1 (en) | 2009-03-26 |
| US8080542B2 (en) | 2011-12-20 |
| EP2188252B1 (en) | 2011-04-13 |
| AU2008302746B2 (en) | 2014-07-03 |
| EP2188252A2 (en) | 2010-05-26 |
| DE602008006209D1 (de) | 2011-05-26 |
| ATE505454T1 (de) | 2011-04-15 |
| US20120088749A1 (en) | 2012-04-12 |
| US20090082331A1 (en) | 2009-03-26 |
| CA2699417A1 (en) | 2009-03-26 |
| WO2009038759A3 (en) | 2009-07-23 |
| WO2009038759A2 (en) | 2009-03-26 |
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