JP2010539180A5 - - Google Patents

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Publication number
JP2010539180A5
JP2010539180A5 JP2010524978A JP2010524978A JP2010539180A5 JP 2010539180 A5 JP2010539180 A5 JP 2010539180A5 JP 2010524978 A JP2010524978 A JP 2010524978A JP 2010524978 A JP2010524978 A JP 2010524978A JP 2010539180 A5 JP2010539180 A5 JP 2010539180A5
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JP
Japan
Prior art keywords
pyrrolidin
ylethyl
oxo
tetrahydroisoquinolin
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010524978A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010539180A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/075981 external-priority patent/WO2009036144A1/en
Publication of JP2010539180A publication Critical patent/JP2010539180A/ja
Publication of JP2010539180A5 publication Critical patent/JP2010539180A5/ja
Withdrawn legal-status Critical Current

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JP2010524978A 2007-09-12 2008-09-11 ヒスタミン３拮抗薬としてのイソキノリニルおよびイソインドリニル誘導体 Withdrawn JP2010539180A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99363607P 2007-09-12 2007-09-12
PCT/US2008/075981 WO2009036144A1 (en) 2007-09-12 2008-09-11 Isoquinolinyl and isoindolinyl derivatives as histamine-3 antagonists

Publications (2)

Publication Number Publication Date
JP2010539180A JP2010539180A (ja) 2010-12-16
JP2010539180A5 true JP2010539180A5 (https=) 2011-09-29

Family

ID=40261509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010524978A Withdrawn JP2010539180A (ja) 2007-09-12 2008-09-11 ヒスタミン３拮抗薬としてのイソキノリニルおよびイソインドリニル誘導体

Country Status (25)

Country Link
US (1) US20090069300A1 (https=)
EP (1) EP2200989A1 (https=)
JP (1) JP2010539180A (https=)
KR (1) KR20100054856A (https=)
CN (1) CN101848896A (https=)
AP (1) AP2010005202A0 (https=)
AR (1) AR068423A1 (https=)
AU (1) AU2008298926A1 (https=)
BR (1) BRPI0817061A2 (https=)
CA (1) CA2699384A1 (https=)
CL (1) CL2008002726A1 (https=)
CO (1) CO6300955A2 (https=)
CR (1) CR11303A (https=)
DO (1) DOP2010000079A (https=)
EA (1) EA201000316A1 (https=)
EC (1) ECSP10010025A (https=)
MA (1) MA31699B1 (https=)
MX (1) MX2010002760A (https=)
NI (1) NI201000036A (https=)
PA (1) PA8795701A1 (https=)
PE (1) PE20090651A1 (https=)
TN (1) TN2010000105A1 (https=)
TW (1) TW200927114A (https=)
WO (1) WO2009036144A1 (https=)
ZA (1) ZA201001751B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200823204A (en) * 2006-10-17 2008-06-01 Arena Pharm Inc Biphenyl sulfonyl and phenyl-heteroaryl sulfonyl modulators of the histamine H3-receptor useful for the treatment of disorders related thereto
GB0907284D0 (en) 2009-04-28 2009-06-10 Queen Mary & Westfield College Compounds for inducing cellular apoptosis
ES2642586T3 (es) * 2009-07-27 2017-11-16 Gilead Sciences, Inc. Compuestos heterocíclicos condensados como moduladores de canales iónicos
EP2588197B1 (en) 2010-07-02 2014-11-05 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
EP2632461A4 (en) * 2010-10-29 2014-04-02 Merck Sharp & Dohme Isoindolinone PDE10 INHIBITORS
KR20140033377A (ko) * 2011-05-10 2014-03-18 길리애드 사이언시즈, 인코포레이티드 나트륨 채널 조절제로서의 융합된 헤테로시클릭 화합물
NO3175985T3 (https=) 2011-07-01 2018-04-28
UY34171A (es) 2011-07-01 2013-01-31 Gilead Sciences Inc Compuestos heterocíclicos fusionados como moduladores del canal iónico
JP2014520776A (ja) 2011-07-04 2014-08-25 バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー 植物における非生物的ストレスに対する活性薬剤としての置換されているイソキノリノン類、イソキノリンジオン類、イソキノリントリオン類およびジヒドロイソキノリノン類または各場合でのそれらの塩の使用
WO2013076590A1 (en) 2011-11-23 2013-05-30 Oxygen Healthcare Research Pvt. Ltd Benzothiazine compounds as h3 receptor ligands
CN105254554B (zh) * 2014-07-14 2018-01-30 南开大学 一种制备异吲哚啉酮类化合物的方法
JP2023520916A (ja) * 2020-04-08 2023-05-22 リミックス セラピューティクス インコーポレイテッド スプライシングを調整するための化合物及び方法
CA3191279A1 (en) 2020-08-28 2022-03-03 Yi Liu Heterocyclic compounds and uses thereof
US12496297B1 (en) * 2020-10-23 2025-12-16 Washington University Compositions of autophagy modulating agents and uses thereof
CN115819347B (zh) * 2022-11-14 2024-08-30 暨明医药科技（苏州）有限公司 一种1-烷基-3-溴吡唑的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933829A (en) * 1974-08-22 1976-01-20 John Wyeth & Brother Limited 4-Aminoquinoline derivatives
US4166853A (en) * 1978-05-05 1979-09-04 The Upjohn Company Antihypertensive 7-trifluoromethyl-4-aminoquinolones
US4159331A (en) * 1978-05-05 1979-06-26 The Upjohn Company Antihypertensive 4-aminoquinolines
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
ES2210747T3 (es) * 1997-05-01 2004-07-01 Eli Lilly And Company Agentes antitromboticos.
JP2004532834A (ja) 2001-03-23 2004-10-28 イーライ・リリー・アンド・カンパニー ヒスタミンｈ３受容体アンタゴニストである非イミダゾール系アリールアルキルアミン化合物、その製造および治療的使用
KR101025633B1 (ko) * 2002-09-19 2011-03-30 일라이 릴리 앤드 캄파니 오피오이드 수용체 안타고니스트로서의 디아릴 에테르
AU2005243175B2 (en) * 2004-05-14 2011-12-01 Millennium Pharmaceuticals, Inc. Compounds and methods for inhibiting mitotic progression by inhibition of Aurora kinase
US20060014733A1 (en) * 2004-07-19 2006-01-19 Pfizer Inc Histamine-3 agonists and antagonists
US7381732B2 (en) * 2004-10-26 2008-06-03 Bristol-Myers Squibb Company Pyrazolobenzamides and derivatives as factor Xa inhibitors
EP1848696A1 (en) * 2005-01-21 2007-10-31 Schering Corporation Imidazole and benzimidazole derivates useful as histamine h3 antagonists
JP2008537953A (ja) * 2005-04-15 2008-10-02 エラン ファーマシューティカルズ，インコーポレイテッド ブラジキニンｂ１受容体拮抗作用に有用な新規化合物

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