JP2010537961A5 - - Google Patents
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- Publication number
- JP2010537961A5 JP2010537961A5 JP2010522440A JP2010522440A JP2010537961A5 JP 2010537961 A5 JP2010537961 A5 JP 2010537961A5 JP 2010522440 A JP2010522440 A JP 2010522440A JP 2010522440 A JP2010522440 A JP 2010522440A JP 2010537961 A5 JP2010537961 A5 JP 2010537961A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- influenza
- antigen
- fluorocarbon vector
- fluorocarbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 claims 18
- 239000000427 antigen Substances 0.000 claims 17
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 239000002671 adjuvant Substances 0.000 claims 7
- 206010022000 influenza Diseases 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 229940021993 prophylactic vaccine Drugs 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 230000000699 topical effect Effects 0.000 claims 3
- 241000712461 unidentified influenza virus Species 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 229960003971 influenza vaccine Drugs 0.000 claims 2
- BSOQXXWZTUDTEL-ZUYCGGNHSA-N muramyl dipeptide Chemical compound OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O BSOQXXWZTUDTEL-ZUYCGGNHSA-N 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 108010042708 Acetylmuramyl-Alanyl-Isoglutamine Proteins 0.000 claims 1
- 231100000699 Bacterial toxin Toxicity 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 229940123424 Neuraminidase inhibitor Drugs 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000000688 bacterial toxin Substances 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 230000008348 humoral response Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 230000001024 immunotherapeutic effect Effects 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 208000037797 influenza A Diseases 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 229930182490 saponin Natural products 0.000 claims 1
- 150000007949 saponins Chemical class 0.000 claims 1
- 235000017709 saponins Nutrition 0.000 claims 1
- 239000002911 sialidase inhibitor Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0716992.3 | 2007-08-31 | ||
| GBGB0716992.3A GB0716992D0 (en) | 2007-08-31 | 2007-08-31 | Influenza antigen delivery vectors and constructs |
| PCT/GB2008/002930 WO2009027688A1 (en) | 2007-08-31 | 2008-08-29 | Influenza antigen delivery vectors and constructs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013123602A Division JP2013241414A (ja) | 2007-08-31 | 2013-06-12 | インフルエンザ抗原送達用のベクターおよび構築体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010537961A JP2010537961A (ja) | 2010-12-09 |
| JP2010537961A5 true JP2010537961A5 (enExample) | 2012-06-28 |
| JP5756630B2 JP5756630B2 (ja) | 2015-07-29 |
Family
ID=38617093
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522440A Expired - Fee Related JP5756630B2 (ja) | 2007-08-31 | 2008-08-29 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2013123602A Pending JP2013241414A (ja) | 2007-08-31 | 2013-06-12 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2016041049A Withdrawn JP2016155829A (ja) | 2007-08-31 | 2016-03-03 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2017250464A Expired - Fee Related JP6826027B2 (ja) | 2007-08-31 | 2017-12-27 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2020160511A Pending JP2021001216A (ja) | 2007-08-31 | 2020-09-25 | インフルエンザ抗原送達用のベクターおよび構築体 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013123602A Pending JP2013241414A (ja) | 2007-08-31 | 2013-06-12 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2016041049A Withdrawn JP2016155829A (ja) | 2007-08-31 | 2016-03-03 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2017250464A Expired - Fee Related JP6826027B2 (ja) | 2007-08-31 | 2017-12-27 | インフルエンザ抗原送達用のベクターおよび構築体 |
| JP2020160511A Pending JP2021001216A (ja) | 2007-08-31 | 2020-09-25 | インフルエンザ抗原送達用のベクターおよび構築体 |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US8642531B2 (enExample) |
| EP (2) | EP2190474B1 (enExample) |
| JP (5) | JP5756630B2 (enExample) |
| KR (3) | KR101736897B1 (enExample) |
| CN (1) | CN101827607A (enExample) |
| AR (1) | AR068507A1 (enExample) |
| AU (1) | AU2008291974B2 (enExample) |
| BR (1) | BRPI0815836A2 (enExample) |
| CA (1) | CA2697729C (enExample) |
| CL (1) | CL2008002559A1 (enExample) |
| CY (1) | CY1115598T1 (enExample) |
| DK (2) | DK2190474T3 (enExample) |
| EA (1) | EA018765B1 (enExample) |
| ES (2) | ES2488941T3 (enExample) |
| GB (2) | GB0716992D0 (enExample) |
| HR (1) | HRP20140765T1 (enExample) |
| MX (1) | MX2010002335A (enExample) |
| PL (1) | PL2190474T3 (enExample) |
| PT (1) | PT2190474E (enExample) |
| SI (1) | SI2190474T1 (enExample) |
| TW (2) | TW201345551A (enExample) |
| WO (1) | WO2009027688A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0408164D0 (en) * | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| GB0716992D0 (en) | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| WO2009129227A1 (en) | 2008-04-17 | 2009-10-22 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
| US20110165037A1 (en) * | 2010-01-07 | 2011-07-07 | Ismagilov Rustem F | Interfaces that eliminate non-specific adsorption, and introduce specific interactions |
| JP2013540425A (ja) | 2010-08-03 | 2013-11-07 | ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーション | インフルエンザ感染の治療および制限のうち少なくとも一方を行うためのポリペプチド |
| CN103282375B (zh) | 2010-12-02 | 2017-01-11 | 比奥诺尔免疫有限公司 | 肽支架设计 |
| GB201022147D0 (en) * | 2010-12-31 | 2011-02-16 | Immune Targeting Systems Its Ltd | Formulation |
| CN102133396B (zh) * | 2011-03-16 | 2013-10-16 | 中国人民解放军第三〇二医院 | 一种疫苗注射剂及其制备方法 |
| WO2013093514A2 (en) * | 2011-12-23 | 2013-06-27 | Retroscreen Virology Ltd | Vaccines - peptides |
| EP2800576A2 (en) | 2012-03-13 | 2014-11-12 | University Of Washington Through Its Center For Commercialization | Polypeptides for treating and/or limiting influenza infection |
| CN105163753B (zh) | 2012-06-15 | 2018-12-21 | Pds生物科技公司 | 阳离子脂质疫苗组合物和使用方法 |
| EP2897639A4 (en) | 2012-09-21 | 2016-05-04 | Frank Bedu-Addo | IMPROVED VACCINATE COMPOSITIONS AND METHODS OF USE |
| GB201321242D0 (en) | 2013-12-02 | 2014-01-15 | Immune Targeting Systems Its Ltd | Immunogenic compound |
| WO2015143339A2 (en) | 2014-03-21 | 2015-09-24 | University Of Washington | Enhanced influenza hemagglutinin binders |
| WO2015157189A1 (en) * | 2014-04-07 | 2015-10-15 | The Regents Of The University Of California | Vaccines and uses thereof |
| JP6103547B2 (ja) * | 2015-01-09 | 2017-03-29 | 三菱電機株式会社 | 電子基板ユニット |
| CA3005251A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| EP3257864A1 (en) * | 2016-06-16 | 2017-12-20 | Université de Strasbourg | Metabolically stable spexin peptide analogs |
| EP3257863A1 (en) * | 2016-06-16 | 2017-12-20 | Université de Strasbourg | Flourous metabolically stable peptide analogs |
| CN110035765B (zh) * | 2016-10-05 | 2024-04-02 | Pds生物科技公司 | 新型hpv16非hla限制性t细胞疫苗、组合物及其使用方法 |
| CN111148528A (zh) | 2016-12-28 | 2020-05-12 | 英福瓦克思公司 | 流感疫苗 |
| WO2019046901A1 (en) * | 2017-09-08 | 2019-03-14 | The University Of Melbourne | METHODS AND COMPOSITIONS FOR PREVENTING INFLUENZA INFECTION |
| EP3773710A4 (en) * | 2018-04-04 | 2022-03-16 | Altimmune Inc | COMBINATIONS OF VACCINE COMPOSITIONS INDUCING T LYMPHOCYTES AND THEIR USES |
| JP7037994B2 (ja) | 2018-04-11 | 2022-03-17 | 株式会社シマノ | 制御装置、人力駆動車、および制御方法 |
| CN110772635B (zh) * | 2019-11-11 | 2023-01-31 | 扬州大学 | 流感病毒小体包被的仿生纳米疫苗及其制备方法 |
| EP4172897A1 (en) * | 2020-06-29 | 2023-05-03 | Seqirus UK Limited | Adaptive vaccine stockpile |
| CN119306833B (zh) * | 2023-07-11 | 2025-09-16 | 东莞市朋志生物科技有限公司 | 抗降钙素原抗体、检测降钙素原的试剂和试剂盒 |
| CN117430664B (zh) * | 2023-10-24 | 2024-04-09 | 暨南大学附属第六医院(东莞市东部中心医院) | 一种甲型流感病毒t细胞抗原表位肽及其应用 |
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| US4332787A (en) * | 1980-06-23 | 1982-06-01 | The Massachusetts General Hospital | Assay for beta-adrenergic antagonists and antibody therefor |
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| US4716102A (en) * | 1984-08-15 | 1987-12-29 | Regents Of The University Of California | Purified AIDS-associated virus ARV-2 |
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| US4954444A (en) | 1987-03-02 | 1990-09-04 | E. I. Du Pont De Nemours And Company | Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports |
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| US5817318A (en) * | 1989-05-03 | 1998-10-06 | Connaught Laboratories Limited | Synthetic peptides for an HIV-1 vaccine |
| EP0529007A1 (en) * | 1990-04-18 | 1993-03-03 | The Regents Of The University Of California | A 35kD TUMOR ASSOCIATED PROTEIN ANTIGEN: USES AND METHODS OF DETECTION |
| ATE194657T1 (de) * | 1990-09-25 | 2000-07-15 | Cantab Pharma Res | Bei einer transkomplementenden zellinie erzeugter defektiver virenimpfstoff |
| US5871746A (en) * | 1990-12-18 | 1999-02-16 | Institut National De La Sainte Et De La Recherche Medicale (Inserm) | Cytotoxic T lymphocyte-inducing lipopeptides and use as vaccines |
| JPH07500483A (ja) * | 1991-03-14 | 1995-01-19 | ブリティッシュ・テクノロジー・グループ・ユーエスエイ・インコーポレーテッド | 組換え体抗コクシジアワクチン |
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| EP0756604A1 (en) * | 1994-04-22 | 1997-02-05 | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services | Melanoma antigens |
| GB9420146D0 (en) * | 1994-10-06 | 1994-11-23 | Cancer Res Campaign Tech | Papillomavirus vaccine |
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| GB0716992D0 (en) | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
| GB0408164D0 (en) * | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| CN101116057B (zh) | 2004-12-30 | 2011-10-05 | 英特尔公司 | 在多个指令定序器上基于指令集的线程执行机制 |
| FR2883563B1 (fr) | 2005-03-24 | 2007-06-01 | Ts Pharma Sarl | Nouveaux vecteurs cationiques bolaformes hemifluorocarbones et leurs applications |
| HUE049580T2 (hu) * | 2006-01-27 | 2020-09-28 | Seqirus Uk Ltd | Hemagglutinint és mátrixfehérjéket tartalmazó, influenza elleni oltóanyagok |
| GB0613977D0 (en) | 2006-02-07 | 2006-08-23 | Peptcell Ltd | Peptide sequences and compositions |
| WO2007091387A1 (ja) * | 2006-02-07 | 2007-08-16 | Nec Corporation | Ｈｌａ結合性ペプチド、その前駆体、それをコードするｄｎａ断片および組み換えベクター |
| GB201022147D0 (en) | 2010-12-31 | 2011-02-16 | Immune Targeting Systems Its Ltd | Formulation |
-
2007
- 2007-08-31 GB GBGB0716992.3A patent/GB0716992D0/en not_active Ceased
-
2008
- 2008-08-29 SI SI200831254T patent/SI2190474T1/sl unknown
- 2008-08-29 ES ES08788477.1T patent/ES2488941T3/es active Active
- 2008-08-29 DK DK08788477.1T patent/DK2190474T3/da active
- 2008-08-29 KR KR1020157014046A patent/KR101736897B1/ko not_active Expired - Fee Related
- 2008-08-29 EA EA201070329A patent/EA018765B1/ru not_active IP Right Cessation
- 2008-08-29 EP EP08788477.1A patent/EP2190474B1/en active Active
- 2008-08-29 JP JP2010522440A patent/JP5756630B2/ja not_active Expired - Fee Related
- 2008-08-29 CA CA2697729A patent/CA2697729C/en active Active
- 2008-08-29 US US12/201,894 patent/US8642531B2/en active Active
- 2008-08-29 CL CL2008002559A patent/CL2008002559A1/es unknown
- 2008-08-29 BR BRPI0815836-3A2A patent/BRPI0815836A2/pt not_active Application Discontinuation
- 2008-08-29 ES ES14160760T patent/ES2741729T3/es active Active
- 2008-08-29 KR KR1020107006993A patent/KR101665141B1/ko not_active Expired - Fee Related
- 2008-08-29 GB GB1005395A patent/GB2465733B/en not_active Expired - Fee Related
- 2008-08-29 WO PCT/GB2008/002930 patent/WO2009027688A1/en not_active Ceased
- 2008-08-29 PL PL08788477T patent/PL2190474T3/pl unknown
- 2008-08-29 CN CN200880111908A patent/CN101827607A/zh active Pending
- 2008-08-29 AU AU2008291974A patent/AU2008291974B2/en not_active Ceased
- 2008-08-29 KR KR1020167036184A patent/KR20170001729A/ko not_active Ceased
- 2008-08-29 PT PT87884771T patent/PT2190474E/pt unknown
- 2008-08-29 EP EP14160760.6A patent/EP2762164B1/en not_active Not-in-force
- 2008-08-29 DK DK14160760.6T patent/DK2762164T3/da active
- 2008-08-29 HR HRP20140765AT patent/HRP20140765T1/hr unknown
- 2008-08-29 MX MX2010002335A patent/MX2010002335A/es active IP Right Grant
- 2008-09-01 TW TW102127018A patent/TW201345551A/zh unknown
- 2008-09-01 TW TW97133417A patent/TWI469790B/zh not_active IP Right Cessation
- 2008-09-01 AR ARP080103803A patent/AR068507A1/es unknown
-
2013
- 2013-06-12 JP JP2013123602A patent/JP2013241414A/ja active Pending
- 2013-12-23 US US14/139,293 patent/US9446143B2/en not_active Expired - Fee Related
-
2014
- 2014-08-13 CY CY20141100646T patent/CY1115598T1/el unknown
-
2016
- 2016-03-03 JP JP2016041049A patent/JP2016155829A/ja not_active Withdrawn
- 2016-08-22 US US15/242,682 patent/US10155049B2/en active Active
-
2017
- 2017-12-27 JP JP2017250464A patent/JP6826027B2/ja not_active Expired - Fee Related
-
2018
- 2018-11-11 US US16/186,558 patent/US20210316000A9/en not_active Abandoned
-
2020
- 2020-09-25 JP JP2020160511A patent/JP2021001216A/ja active Pending
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