JP2010536739A5 - - Google Patents

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Publication number
JP2010536739A5
JP2010536739A5 JP2010520640A JP2010520640A JP2010536739A5 JP 2010536739 A5 JP2010536739 A5 JP 2010536739A5 JP 2010520640 A JP2010520640 A JP 2010520640A JP 2010520640 A JP2010520640 A JP 2010520640A JP 2010536739 A5 JP2010536739 A5 JP 2010536739A5
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JP
Japan
Prior art keywords
polymer
motif
uracil
cytosine
outside
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JP2010520640A
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English (en)
Japanese (ja)
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JP2010536739A (ja
JP4847609B2 (ja
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Priority claimed from PCT/IB2008/002104 external-priority patent/WO2009022216A2/en
Publication of JP2010536739A publication Critical patent/JP2010536739A/ja
Publication of JP2010536739A5 publication Critical patent/JP2010536739A5/ja
Application granted granted Critical
Publication of JP4847609B2 publication Critical patent/JP4847609B2/ja
Active legal-status Critical Current
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JP2010520640A 2007-08-13 2008-08-08 特異的な免疫修飾プロフィールを誘発する規定されたヌクレオチド間結合との関連におけるｒｎａ配列モチーフ Active JP4847609B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96444807P 2007-08-13 2007-08-13
US60/964,448 2007-08-13
PCT/IB2008/002104 WO2009022216A2 (en) 2007-08-13 2008-08-08 Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles

Publications (3)

Publication Number Publication Date
JP2010536739A JP2010536739A (ja) 2010-12-02
JP2010536739A5 true JP2010536739A5 (https=) 2011-01-20
JP4847609B2 JP4847609B2 (ja) 2011-12-28

Family

ID=40351228

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010520640A Active JP4847609B2 (ja) 2007-08-13 2008-08-08 特異的な免疫修飾プロフィールを誘発する規定されたヌクレオチド間結合との関連におけるｒｎａ配列モチーフ

Country Status (22)

Country Link
US (3) US8128944B2 (https=)
EP (1) EP2179039B1 (https=)
JP (1) JP4847609B2 (https=)
KR (1) KR20100045508A (https=)
CN (1) CN101821392B (https=)
AR (1) AR067928A1 (https=)
AU (1) AU2008288241B2 (https=)
BR (1) BRPI0814260B8 (https=)
CA (1) CA2696630C (https=)
CL (1) CL2008002371A1 (https=)
CO (1) CO6260153A2 (https=)
DK (1) DK2179039T3 (https=)
ES (1) ES2703876T3 (https=)
MX (1) MX2010001014A (https=)
NZ (1) NZ582972A (https=)
PL (1) PL2179039T3 (https=)
PT (1) PT2179039T (https=)
RU (1) RU2435851C2 (https=)
SI (1) SI2179039T1 (https=)
TR (1) TR201820474T4 (https=)
TW (1) TW200916106A (https=)
WO (1) WO2009022216A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100045508A (ko) * 2007-08-13 2010-05-03 콜리 파마슈티칼 게엠베하 특이적 면역 조절 프로필을 유도하는 규정된 뉴클레오티드간 연결의 환경에서의 ｒｎａ 서열 모티프
WO2009027105A2 (en) * 2007-08-31 2009-03-05 Neurimmune Therapeutics Ag Method of providing patient specific immune response in amyloidoses and protein aggregation disorders
WO2009105641A2 (en) 2008-02-20 2009-08-27 New York University Preventing and treating amyloid-beta deposition by stimulation of innate immunity
WO2013012875A2 (en) 2011-07-18 2013-01-24 Mount Sinai School Of Medicine Bacterial rnas as vaccine adjuvants
TR201908550T4 (tr) 2014-06-04 2019-07-22 Exicure Inc Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi.
US11213593B2 (en) 2014-11-21 2022-01-04 Northwestern University Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
WO2018039629A2 (en) 2016-08-25 2018-03-01 Northwestern University Micellar spherical nucleic acids from thermoresponsive, traceless templates
WO2018209270A1 (en) 2017-05-11 2018-11-15 Northwestern University Adoptive cell therapy using spherical nucleic acids (snas)
CR20200260A (es) * 2017-12-15 2020-08-01 Bayer Animal Health Gmbh Composiciones inmunoestimulantes
WO2024030844A1 (en) * 2022-08-01 2024-02-08 University Of Mississippi Choline carboxylic acid based ionic liquids as antimicrobial agents

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
US5817321A (en) * 1992-10-08 1998-10-06 Supratek Pharma, Inc. Biological agent compositions
IL112920A (en) * 1994-03-07 2003-04-10 Dow Chemical Co Composition comprising a dendritic polymer complexed with at least one unit of biological response modifier and a process for the preparation thereof
DE60021354T2 (de) * 1999-02-15 2006-04-27 Nippon Shinyaku Co., Ltd. Polynukleotide mit gekürzter kette und verfahren zu ihrer herstellung
RU2288921C2 (ru) * 2000-12-19 2006-12-10 Калифорниа Инститьют оф Текнолоджи Композиции, содержащие комплексы включения
RU2289410C2 (ru) * 2001-04-04 2006-12-20 Корикса Корпорейшн Профилактика и лечение инфекционных и других заболеваний с помощью соединений, основанных на моно- и дисахаридах
RU2185818C1 (ru) * 2001-07-10 2002-07-27 НИИ "Молекулярной медицины" Московской медицинской академии им. И.М. Сеченова Композиция для лечения легочных инфекций
ATE411054T1 (de) 2001-08-17 2008-10-15 Coley Pharm Gmbh Kombinations-motif-immunstimulierende oligonukleotide mit verbesserter wirkung
EP3006043B1 (en) * 2002-04-04 2019-05-29 Zoetis Belgium S.A. Immunostimulatory g,u-containing oligoribonucleotides
AU2003236258A1 (en) 2002-04-12 2003-10-27 Aisin Aw Co., Ltd. Power supply management system for vehicle mounted apparatus
DE10229872A1 (de) * 2002-07-03 2004-01-29 Curevac Gmbh Immunstimulation durch chemisch modifizierte RNA
CA2502015A1 (en) 2002-12-11 2004-06-24 Coley Pharmaceutical Group, Inc. 5' cpg nucleic acids and methods of use
MXPA06000619A (es) * 2003-07-15 2006-04-11 Hybridon Inc Estimulacion sinergistica del sistema inmune usando oligonucleotidos inmunoestimuladores y/o compuestos inmunomeros en conjunto con citocinas y/o agentes quimioterapeuticos o terapia de radiacion.
US20050239733A1 (en) * 2003-10-31 2005-10-27 Coley Pharmaceutical Gmbh Sequence requirements for inhibitory oligonucleotides
JP2007526253A (ja) * 2004-02-19 2007-09-13 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫刺激性ウイルスｒｎａオリゴヌクレオチド
MY159370A (en) * 2004-10-20 2016-12-30 Coley Pharm Group Inc Semi-soft-class immunostimulatory oligonucleotides
EP1924284A1 (en) * 2005-09-14 2008-05-28 Hartmann, Gunther Compositions comprising immunostimulatory rna oligonucleotides and methods for producing said rna oligonucleotides
JP4538522B2 (ja) * 2005-11-25 2010-09-08 コーリー ファーマシューティカル ゲーエムベーハー 免疫刺激性オリゴリボヌクレオチド
KR20100045508A (ko) 2007-08-13 2010-05-03 콜리 파마슈티칼 게엠베하 특이적 면역 조절 프로필을 유도하는 규정된 뉴클레오티드간 연결의 환경에서의 ｒｎａ 서열 모티프

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