AR067928A1 - Motivos de secuencias de arn en el contexto de uniones de internucleotidos definidas que inducen perfiles inmunomoduladores especificos - Google Patents
Motivos de secuencias de arn en el contexto de uniones de internucleotidos definidas que inducen perfiles inmunomoduladores especificosInfo
- Publication number
- AR067928A1 AR067928A1 ARP080103532A ARP080103532A AR067928A1 AR 067928 A1 AR067928 A1 AR 067928A1 AR P080103532 A ARP080103532 A AR P080103532A AR P080103532 A ARP080103532 A AR P080103532A AR 067928 A1 AR067928 A1 AR 067928A1
- Authority
- AR
- Argentina
- Prior art keywords
- unions
- profiles
- reasons
- context
- rna sequences
- Prior art date
Links
- 239000002955 immunomodulating agent Substances 0.000 title 1
- 229940121354 immunomodulator Drugs 0.000 title 1
- 230000002584 immunomodulator Effects 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 4
- 229920000642 polymer Polymers 0.000 abstract 4
- 230000001419 dependent effect Effects 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 101000669402 Homo sapiens Toll-like receptor 7 Proteins 0.000 abstract 1
- 102000002689 Toll-like receptor Human genes 0.000 abstract 1
- 108020000411 Toll-like receptor Proteins 0.000 abstract 1
- 102100039390 Toll-like receptor 7 Human genes 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96444807P | 2007-08-13 | 2007-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR067928A1 true AR067928A1 (es) | 2009-10-28 |
Family
ID=40351228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080103532A AR067928A1 (es) | 2007-08-13 | 2008-08-13 | Motivos de secuencias de arn en el contexto de uniones de internucleotidos definidas que inducen perfiles inmunomoduladores especificos |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US8128944B2 (https=) |
| EP (1) | EP2179039B1 (https=) |
| JP (1) | JP4847609B2 (https=) |
| KR (1) | KR20100045508A (https=) |
| CN (1) | CN101821392B (https=) |
| AR (1) | AR067928A1 (https=) |
| AU (1) | AU2008288241B2 (https=) |
| BR (1) | BRPI0814260B8 (https=) |
| CA (1) | CA2696630C (https=) |
| CL (1) | CL2008002371A1 (https=) |
| CO (1) | CO6260153A2 (https=) |
| DK (1) | DK2179039T3 (https=) |
| ES (1) | ES2703876T3 (https=) |
| MX (1) | MX2010001014A (https=) |
| NZ (1) | NZ582972A (https=) |
| PL (1) | PL2179039T3 (https=) |
| PT (1) | PT2179039T (https=) |
| RU (1) | RU2435851C2 (https=) |
| SI (1) | SI2179039T1 (https=) |
| TR (1) | TR201820474T4 (https=) |
| TW (1) | TW200916106A (https=) |
| WO (1) | WO2009022216A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100045508A (ko) * | 2007-08-13 | 2010-05-03 | 콜리 파마슈티칼 게엠베하 | 특이적 면역 조절 프로필을 유도하는 규정된 뉴클레오티드간 연결의 환경에서의 ｒｎａ 서열 모티프 |
| WO2009027105A2 (en) * | 2007-08-31 | 2009-03-05 | Neurimmune Therapeutics Ag | Method of providing patient specific immune response in amyloidoses and protein aggregation disorders |
| WO2009105641A2 (en) | 2008-02-20 | 2009-08-27 | New York University | Preventing and treating amyloid-beta deposition by stimulation of innate immunity |
| WO2013012875A2 (en) | 2011-07-18 | 2013-01-24 | Mount Sinai School Of Medicine | Bacterial rnas as vaccine adjuvants |
| TR201908550T4 (tr) | 2014-06-04 | 2019-07-22 | Exicure Inc | Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi. |
| US11213593B2 (en) | 2014-11-21 | 2022-01-04 | Northwestern University | Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates |
| WO2018039629A2 (en) | 2016-08-25 | 2018-03-01 | Northwestern University | Micellar spherical nucleic acids from thermoresponsive, traceless templates |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| CR20200260A (es) * | 2017-12-15 | 2020-08-01 | Bayer Animal Health Gmbh | Composiciones inmunoestimulantes |
| WO2024030844A1 (en) * | 2022-08-01 | 2024-02-08 | University Of Mississippi | Choline carboxylic acid based ionic liquids as antimicrobial agents |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817321A (en) * | 1992-10-08 | 1998-10-06 | Supratek Pharma, Inc. | Biological agent compositions |
| IL112920A (en) * | 1994-03-07 | 2003-04-10 | Dow Chemical Co | Composition comprising a dendritic polymer complexed with at least one unit of biological response modifier and a process for the preparation thereof |
| DE60021354T2 (de) * | 1999-02-15 | 2006-04-27 | Nippon Shinyaku Co., Ltd. | Polynukleotide mit gekürzter kette und verfahren zu ihrer herstellung |
| RU2288921C2 (ru) * | 2000-12-19 | 2006-12-10 | Калифорниа Инститьют оф Текнолоджи | Композиции, содержащие комплексы включения |
| RU2289410C2 (ru) * | 2001-04-04 | 2006-12-20 | Корикса Корпорейшн | Профилактика и лечение инфекционных и других заболеваний с помощью соединений, основанных на моно- и дисахаридах |
| RU2185818C1 (ru) * | 2001-07-10 | 2002-07-27 | НИИ "Молекулярной медицины" Московской медицинской академии им. И.М. Сеченова | Композиция для лечения легочных инфекций |
| ATE411054T1 (de) | 2001-08-17 | 2008-10-15 | Coley Pharm Gmbh | Kombinations-motif-immunstimulierende oligonukleotide mit verbesserter wirkung |
| EP3006043B1 (en) * | 2002-04-04 | 2019-05-29 | Zoetis Belgium S.A. | Immunostimulatory g,u-containing oligoribonucleotides |
| AU2003236258A1 (en) | 2002-04-12 | 2003-10-27 | Aisin Aw Co., Ltd. | Power supply management system for vehicle mounted apparatus |
| DE10229872A1 (de) * | 2002-07-03 | 2004-01-29 | Curevac Gmbh | Immunstimulation durch chemisch modifizierte RNA |
| CA2502015A1 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5' cpg nucleic acids and methods of use |
| MXPA06000619A (es) * | 2003-07-15 | 2006-04-11 | Hybridon Inc | Estimulacion sinergistica del sistema inmune usando oligonucleotidos inmunoestimuladores y/o compuestos inmunomeros en conjunto con citocinas y/o agentes quimioterapeuticos o terapia de radiacion. |
| US20050239733A1 (en) * | 2003-10-31 | 2005-10-27 | Coley Pharmaceutical Gmbh | Sequence requirements for inhibitory oligonucleotides |
| JP2007526253A (ja) * | 2004-02-19 | 2007-09-13 | コーリー ファーマシューティカル グループ，インコーポレイテッド | 免疫刺激性ウイルスｒｎａオリゴヌクレオチド |
| MY159370A (en) * | 2004-10-20 | 2016-12-30 | Coley Pharm Group Inc | Semi-soft-class immunostimulatory oligonucleotides |
| EP1924284A1 (en) * | 2005-09-14 | 2008-05-28 | Hartmann, Gunther | Compositions comprising immunostimulatory rna oligonucleotides and methods for producing said rna oligonucleotides |
| JP4538522B2 (ja) * | 2005-11-25 | 2010-09-08 | コーリー ファーマシューティカル ゲーエムベーハー | 免疫刺激性オリゴリボヌクレオチド |
| KR20100045508A (ko) | 2007-08-13 | 2010-05-03 | 콜리 파마슈티칼 게엠베하 | 특이적 면역 조절 프로필을 유도하는 규정된 뉴클레오티드간 연결의 환경에서의 ｒｎａ 서열 모티프 |
-
2008
- 2008-08-08 KR KR1020107005451A patent/KR20100045508A/ko not_active Ceased
- 2008-08-08 CA CA2696630A patent/CA2696630C/en active Active
- 2008-08-08 BR BRPI0814260A patent/BRPI0814260B8/pt active IP Right Grant
- 2008-08-08 CN CN2008801113989A patent/CN101821392B/zh active Active
- 2008-08-08 AU AU2008288241A patent/AU2008288241B2/en active Active
- 2008-08-08 PL PL08789054T patent/PL2179039T3/pl unknown
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