CA2696630C - Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles - Google Patents

Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles Download PDF

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Publication number
CA2696630C
CA2696630C CA2696630A CA2696630A CA2696630C CA 2696630 C CA2696630 C CA 2696630C CA 2696630 A CA2696630 A CA 2696630A CA 2696630 A CA2696630 A CA 2696630A CA 2696630 C CA2696630 C CA 2696630C
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immunostimulatory
seq
polymer
oligoribonucleotide
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CA2696630A1 (en
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Marion Jurk
Jorg Heinz Vollmer
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Zoetis Belgium SA
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Zoetis Belgium SA
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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CA2696630A 2007-08-13 2008-08-08 Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles Active CA2696630C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96444807P 2007-08-13 2007-08-13
US60/964,448 2007-08-13
PCT/IB2008/002104 WO2009022216A2 (en) 2007-08-13 2008-08-08 Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles

Publications (2)

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CA2696630A1 CA2696630A1 (en) 2009-02-19
CA2696630C true CA2696630C (en) 2014-04-01

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CA2696630A Active CA2696630C (en) 2007-08-13 2008-08-08 Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles

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US (3) US8128944B2 (https=)
EP (1) EP2179039B1 (https=)
JP (1) JP4847609B2 (https=)
KR (1) KR20100045508A (https=)
CN (1) CN101821392B (https=)
AR (1) AR067928A1 (https=)
AU (1) AU2008288241B2 (https=)
BR (1) BRPI0814260B8 (https=)
CA (1) CA2696630C (https=)
CL (1) CL2008002371A1 (https=)
CO (1) CO6260153A2 (https=)
DK (1) DK2179039T3 (https=)
ES (1) ES2703876T3 (https=)
MX (1) MX2010001014A (https=)
NZ (1) NZ582972A (https=)
PL (1) PL2179039T3 (https=)
PT (1) PT2179039T (https=)
RU (1) RU2435851C2 (https=)
SI (1) SI2179039T1 (https=)
TR (1) TR201820474T4 (https=)
TW (1) TW200916106A (https=)
WO (1) WO2009022216A2 (https=)

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WO2009027105A2 (en) * 2007-08-31 2009-03-05 Neurimmune Therapeutics Ag Method of providing patient specific immune response in amyloidoses and protein aggregation disorders
WO2009105641A2 (en) 2008-02-20 2009-08-27 New York University Preventing and treating amyloid-beta deposition by stimulation of innate immunity
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US11213593B2 (en) 2014-11-21 2022-01-04 Northwestern University Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
WO2018039629A2 (en) 2016-08-25 2018-03-01 Northwestern University Micellar spherical nucleic acids from thermoresponsive, traceless templates
WO2018209270A1 (en) 2017-05-11 2018-11-15 Northwestern University Adoptive cell therapy using spherical nucleic acids (snas)
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WO2024030844A1 (en) * 2022-08-01 2024-02-08 University Of Mississippi Choline carboxylic acid based ionic liquids as antimicrobial agents

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US8128944B2 (en) 2012-03-06
CO6260153A2 (es) 2011-03-22
CA2696630A1 (en) 2009-02-19
AR067928A1 (es) 2009-10-28
CN101821392B (zh) 2013-04-17
CL2008002371A1 (es) 2009-07-03
EP2179039A2 (en) 2010-04-28
US20120121648A1 (en) 2012-05-17
PT2179039T (pt) 2019-01-11
US8227447B2 (en) 2012-07-24
JP2010536739A (ja) 2010-12-02
US8466124B2 (en) 2013-06-18
AU2008288241A1 (en) 2009-02-19
EP2179039B1 (en) 2018-10-31
RU2010104618A (ru) 2011-09-20
HK1143741A1 (en) 2011-01-14
RU2435851C2 (ru) 2011-12-10
PL2179039T3 (pl) 2019-03-29
KR20100045508A (ko) 2010-05-03
TW200916106A (en) 2009-04-16
WO2009022216A9 (en) 2009-04-30
DK2179039T3 (en) 2019-01-07
TR201820474T4 (tr) 2019-01-21
ES2703876T3 (es) 2019-03-12
AU2008288241B2 (en) 2011-12-01
US20100272785A1 (en) 2010-10-28
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MX2010001014A (es) 2010-03-01
BRPI0814260A2 (pt) 2015-03-31
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US20120258140A1 (en) 2012-10-11
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BRPI0814260B1 (pt) 2019-11-12
NZ582972A (en) 2011-09-30

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