JP2011250796A5 - - Google Patents

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Publication number
JP2011250796A5
JP2011250796A5 JP2011170509A JP2011170509A JP2011250796A5 JP 2011250796 A5 JP2011250796 A5 JP 2011250796A5 JP 2011170509 A JP2011170509 A JP 2011170509A JP 2011170509 A JP2011170509 A JP 2011170509A JP 2011250796 A5 JP2011250796 A5 JP 2011250796A5
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JP
Japan
Prior art keywords
modified
irna agent
sense strand
nucleotide
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011170509A
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English (en)
Japanese (ja)
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JP2011250796A (ja
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Publication date
Application filed filed Critical
Publication of JP2011250796A publication Critical patent/JP2011250796A/ja
Publication of JP2011250796A5 publication Critical patent/JP2011250796A5/ja
Pending legal-status Critical Current

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JP2011170509A 2005-07-21 2011-08-03 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法 Pending JP2011250796A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US70147005P 2005-07-21 2005-07-21
US60/701,470 2005-07-21
US72683805P 2005-10-14 2005-10-14
US60/726,838 2005-10-14
US74831605P 2005-12-07 2005-12-07
US60/748,316 2005-12-07

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2008523010A Division JP2009502138A (ja) 2005-07-21 2006-07-21 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011282081A Division JP2012061007A (ja) 2005-07-21 2011-12-22 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法

Publications (2)

Publication Number Publication Date
JP2011250796A JP2011250796A (ja) 2011-12-15
JP2011250796A5 true JP2011250796A5 (https=) 2012-02-23

Family

ID=37683845

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008523010A Pending JP2009502138A (ja) 2005-07-21 2006-07-21 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法
JP2011170509A Pending JP2011250796A (ja) 2005-07-21 2011-08-03 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法
JP2011282081A Withdrawn JP2012061007A (ja) 2005-07-21 2011-12-22 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2008523010A Pending JP2009502138A (ja) 2005-07-21 2006-07-21 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011282081A Withdrawn JP2012061007A (ja) 2005-07-21 2011-12-22 ＲｈｏＡ遺伝子のＲＮＡｉ調節及びその使用法

Country Status (6)

Country Link
US (3) US20070044161A1 (https=)
EP (2) EP2230305A1 (https=)
JP (3) JP2009502138A (https=)
AU (2) AU2006272808C1 (https=)
CA (1) CA2607668A1 (https=)
WO (2) WO2007014077A2 (https=)

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EP2456456A4 (en) * 2009-07-24 2013-11-20 California Inst Of Techn METHOD AND COMPOSITIONS FOR TREATING NEURAL INJURY OR DEGENERATION
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US8901097B2 (en) 2009-11-08 2014-12-02 Quark Pharmaceuticals, Inc. Methods for delivery of siRNA to the spinal cord and therapies arising therefrom
KR101553753B1 (ko) * 2010-06-24 2015-09-16 쿠아크 파마수티칼스 인코퍼레이티드 Ｒｈｏａ에 대한 이중 가닥 ｒｎａ 및 그의 용도
DK2631291T3 (da) 2010-10-22 2019-06-11 Olix Pharmaceuticals Inc Nukleinsyremolekyler, der inducerer rna-interferens, og anvendelser deraf
CN108148838A (zh) 2012-05-22 2018-06-12 奥利克斯医药有限公司 具有细胞内穿透能力的诱导rna干扰的核酸分子及用途
US9770461B2 (en) 2013-08-02 2017-09-26 California Institute Of Technology Tailored glycopolymers as anticoagulant heparin mimetics
US10227370B2 (en) 2013-08-02 2019-03-12 California Institute Of Technology Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity
JP2018525037A (ja) 2015-08-24 2018-09-06 ハロー−バイオ・アールエヌエーアイ・セラピューティックス、インコーポレイテッド 遺伝子発現の調節のためのポリヌクレオチドナノ粒子及びその使用
US11071791B2 (en) 2018-01-26 2021-07-27 Wisconsin Alumni Research Foundation Vector for gene silencing and replacement and methods of use thereof
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WO2025212926A1 (en) * 2024-04-05 2025-10-09 University Of Massachusetts Aav-mediated rhoa knockdown

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